DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cf2 and zbtb38

DIOPT Version :9

Sequence 1:	NP_001350854.1	Gene:	Cf2 / 33692	FlyBaseID:	FBgn0000286	Length:	537	Species:	Drosophila melanogaster
Sequence 2:	XP_004917884.2	Gene:	zbtb38 / 100488939	XenbaseID:	XB-GENE-983179	Length:	1253	Species:	Xenopus tropicalis

Alignment Length:	254	Identity:	68/254 - (26%)
Similarity:	113/254 - (44%)	Gaps:	32/254 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   228 QQQLQAEHHHQQQHQQQQQQQQQQQELLEQQQREMQEQAQQQQVHHHQQDQDLAGDQVALKVPPL 292
            ::.::.:|...:..:..|..:::::|....:.|: .|.|:.:::.....|||::.....   |..
Frog   818 RKSVRPKHSRSRADKSNQDSEEERKERSSIRLRK-SESAKMEEMCDDPSDQDISDKPWR---PYY 878

  Fly   293 TVKLNKNANGGAIVSHPQVI--IKEEPLSLSDSGDVVNSVPVYAIQANPGVPAPASSGVLVGTQT 355
            ..|..|.:      .|.:..  :|:.....:...||.|:........:..|.....:|.....||
Frog   879 NYKPKKKS------KHFKKFRKLKKRKKHSNKRSDVENNEEADTKDISRNVTEETENGKEENLQT 937

  Fly   356 V---------PADLAH-KIRHK---CPDCPKTFKTPGTLAMHRKIHTGEADATPKERPYTCSYCG 407
            .         ..|::. ::..|   |..|.|:|:.|.||.:|.:.|||       |:||.|..||
Frog   938 AEYTENSAAEDIDVSDWQLASKPCFCELCQKSFRNPSTLKVHMRCHTG-------EKPYPCKTCG 995

  Fly   408 KSFTQSNTLKQHTRIHTGEKPFHCGYCEKSFSVKDYLTKHIRTHTGEKPYTCPYCDKRF 466
            |.|:....|.:|.|||.|.|.|.|.:|.|||.:.:.|.||.|.|||||.|.|.:|.::|
Frog   996 KCFSFPGNLNKHERIHMGVKNFMCQFCSKSFMLNETLKKHERIHTGEKLYGCQFCPQQF 1054

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cf2	NP_001350854.1	COG5048	<366..>473	CDD:227381	46/104 (44%)
		C2H2 Zn finger	368..388	CDD:275368	8/19 (42%)
		C2H2 Zn finger	403..423	CDD:275368	8/19 (42%)
		C2H2 Zn finger	431..451	CDD:275368	9/19 (47%)
		zf-H2C2_2	443..468	CDD:316026	13/24 (54%)
		C2H2 Zn finger	459..480	CDD:275368	3/8 (38%)
zbtb38	XP_004917884.2	BTB_POZ	12..125	CDD:365784
		C2H2 Zn finger	442..462	CDD:275368
		C2H2 Zn finger	470..490	CDD:275368
		C2H2 Zn finger	498..516	CDD:275368
		C2H2 Zn finger	963..983	CDD:275368	8/19 (42%)
		zf-H2C2_2	976..999	CDD:404364	12/29 (41%)
		C2H2 Zn finger	991..1011	CDD:275368	8/19 (42%)
		zf-H2C2_2	1003..1026	CDD:404364	11/22 (50%)
		C2H2 Zn finger	1019..1039	CDD:275368	9/19 (47%)
		C2H2 Zn finger	1047..1067	CDD:275368	3/8 (38%)
		C2H2 Zn finger	1078..1098	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24388
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100