Protein Alignment smog and CG43795

DIOPT Version :10

• Sequence 1: NP_001245881.1
• Gene: smog / 33690
• FlyBaseID: FBgn0051660
• Length: 951
• Species: Drosophila melanogaster
• Sequence 2: NP_001097435.2
• Gene: CG43795 / 5740629
• FlyBaseID: FBgn0264339
• Length: 1420
• Species: Drosophila melanogaster
• Alignment Length: 1136
• Identity: 231/1136 - (20%)
• Similarity: 400/1136 - (35%)
• Gaps: 286/1136 - (25%)

  Fly    35 KKCHQNQTNTQV-QSTQRSNCSSHSDRDHLTNQQKQQNQ-RTNSATAASAAAATLSESTRC--NI 95
            :|.|:.:.|..: :|..:|....|:.::|.:..:.:..| |..|..|...|   |||..:.  .|
  Fly   122 RKLHKKKINESIRKSVDKSLGLRHTPKNHRSLAEAEHLQGRPASEDAEDTA---LSEVMQLADEI 183

  Fly    96 IISSSSSSSSST--------KSSKNIREPSSSSSTQLNTLYSLLVL--------LIVGLATATAS 144
            .:.||..:::.|        ::.:.:|:.::......:|:.....|        :...:....||
  Fly   184 ELESSFVTAAPTGDPDIGVKQARQFVRDEANYQEDDDDTIDDDEELDEEEEEAPMSTTIKPKIAS 248

  Fly   145 PSPSPSHAPFGRESRRDALLAYYKRAHLPQSSSSGISLGHKYHLLHDANGLDFDELTPTASSVSA 209
            ....|.:..:.|       :....|...|:|.....:|.:......:..|..|.:|.|...|::.
  Fly   249 TRLLPVNGTWQR-------MGTISRDSPPESDYDSNALDNAQEDEEEEEGQPFGKLLPLNESLAT 306

  Fly   210 LSRAERFRLRKRSATPTTPATAAGVTSL----DVATAAAAATDAAAKDAGSGKKPEEKCEPKVLE 270
            ....:....|:..|...:.|.:..|..:    |..:.:.|..|.:......|..|:.:.:.|..:
  Fly   307 TEWMDDGAQREPEAEARSQAASMEVKQISFDSDGDSDSEAGLDTSEVTMDDGYPPDAQVDDKTKQ 371

  Fly   271 TLPDEPFYDYTDIAE----------------DAARQFIEF-----LSGKFPNANTPIAIDE---- 310
            .:..:...|..|..|                |...:|:::     |.|....|.|.:.:.|
  Fly   372 LVIGDVEEDSGDNMESNQFTADVINARDSKIDLVSKFLQYIEQQHLMGSNCVAGTSLNLGEGVVD 436

  Fly   311 -------PTRAEVS-RRANGI------ASYALNEDDNLLAFAIAAPSIHTVVVKFRDNV------ 355
                   ...|||: .|||.:      ...::.||.|||..::.:      :|:|.|::
  Fly   437 RYAQDRFRVEAEVAVNRANMLTRIFKTTGRSVQEDVNLLHASVLS------MVEFDDDIFAAGNC 495

  Fly   356 ------------------TIPP---------DQVHNKAYLGS---------------------YW 372
                              .:||         |......|||:                     |.
  Fly   496 FDWNEHPAQPGLFCPFAYRLPPPNLGAVFAKDLAMEYHYLGNTSEWFFLARKNAEKVIARNEQYL 560

  Fly   373 RELGAAWNSTDGTQE------------WGAPFRDC---NLLTRRWLWPFRISF-----SEHRIKV 417
            :......|.|:...|            |..|:.||   |:    |:..:.:.|     ..:..|.
  Fly   561 KSFHLYSNRTEERIEDDTLAVKYEDGRWSKPYYDCGGGNI----WMLTYTVPFFGYENGTYHFKG 621

  Fly   418 VAAAFI---AADEDVC----NDGLE---EVFGRRHGCDRNTTFCLLTENKPAATRDVYTCLCRES 472
            .:...|   ..|.|.|    ..|.:   .:|.....|.:.||.|...... ...|..|.||||:.
  Fly   622 TSGIDIDLRRVDIDQCPQRHTPGTKRPLNIFAGTDKCKQRTTMCEAIMGL-GFRRGSYKCLCRKG 685

  Fly   473 YYLPNSTLQG--FRGDRVELSEGYD--------------NYSCIPCPGGCTNCDSNGVCLTFQEE 521
            :|.|:...|.  |.|..:|  |.|:              .|.|:||..||.:|:.:..|:.
  Fly   686 FYFPDIVSQHKFFNGSLLE--EEYEKLMLGKNSTYNSNSEYECLPCAEGCDSCEDSSPCIA---- 744

  Fly   522 EVLNVDACLRLLVAIVLGACILCCIVLGVI------VFRQRKCKAIASGMWTVLETILLGIVLLY 580
             .||......:|.        |.|||:|::      .||.::.|.:.:....:|..|.||...:|
  Fly   745 -ALNWPMRTSILA--------LACIVIGLLPPAAWFTFRYQQVKVVRAASPALLRVIALGAFFIY 800

  Fly   581 ASVAVHFFPASTERCLLEPWLRELGFITCYGAIILKLYRHLVDFRTRKAHRWVLRDVDLLKYLGT 645
            .:..|.:...:...|....||||:||...|||::||.:|..|.||.|.|....:.|..|||.||.
  Fly   801 CTNIVMYPNPNLYTCTARIWLREIGFSLTYGALMLKTWRISVIFRVRSAKAVKITDAALLKRLGI 865

  Fly   646 MVFAV-ICYMAAFTASSLDLLESAQLESLREADTNTCHPLKWELVTQTSEMLILCFGLHLSIASR 709
            :..|: .|.:.....|..|::.....:.|:   ...|....|:....:.|:|.|.:|:.|.|..|
  Fly   866 ICGAIGTCLLVRTLVSPPDVVVGRTADDLK---AFLCKTDWWDYTFTSMEVLFLAWGVRLCIMVR 927

  Fly   710 NANTQFRERQFLVTALTLEFLVSS----SFYFLRFVYLPEMSPSAILLALFIRSQLTNSFALGLI 770
            .|.::|.|.:|:..|:..|||::.    |..||:    ...:|..:.:..|..:|||.:..|.||
  Fly   928 KAPSEFNESRFISMAIYNEFLLTCFLNVSMLFLQ----SPANPDLLYIIFFCHTQLTVTLLLALI 988

  Fly   771 FVPKLWYQHKQVRSLAYDLSIRLPVDAFKGTSHDAGQRLGGGYAGL---------CLGDP-DIGE 825
            |..|::            :.:|      .|.||.....:|...:|.         ...:| .:..
  Fly   989 FGSKVY------------IVLR------SGKSHQENIGMGTKASGAKFNFRPQVRTFANPSSVTT 1035

  Fly   826 LTI-----SEMSPEDIRAELKRLYTQLE------------IMKNKTLRQ--DNPH----ISKRRG 867
            .|:     :::|.::...|:::|..||:            :|...:|..  ..|.    ::...|
  Fly  1036 STVPVAAETKLSDQEALEEIRQLSMQLQRIQEMAPPKGVAVMTISSLLDGLKTPGGLMVVAAAAG 1100

  Fly   868 GRKAGHR-------------RFSLQKKGSKDKALSAKHRSNKHHQDIEITEAEPSRTPEDSVCSA 919
            ....||.             ...:||...::...:....|.:......:.|..||.|| .|....
  Fly  1101 ATAQGHSAANRQSALPLLALNVEMQKYSQQNNNSNGGRGSGRTSIPTMVLETPPSSTP-PSAAYE 1164

  Fly   920 EGPTDTYAEISG--VSHSMLSHSMVSHSVVS 948
            |...:|  |:||  ....:|..:...|.:.|
  Fly  1165 ERAVNT--ELSGDDFREQLLRRTADGHIICS 1193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smog	NP_001245881.1	7tmC_GPR158-like	529..780	CDD:320420	74/261 (28%)
		TM helix 1	529..554	CDD:320420	6/30 (20%)
		TM helix 2	566..587	CDD:320420	6/20 (30%)
		TM helix 3	596..620	CDD:320420	11/23 (48%)
		TM helix 4	639..659	CDD:320420	7/20 (35%)
		TM helix 5	683..709	CDD:320420	7/25 (28%)
		TM helix 6	717..740	CDD:320420	9/26 (35%)
		TM helix 7	749..774	CDD:320420	8/24 (33%)
CG43795	NP_001097435.2	PDC1_MCP_like	448..629	CDD:350338	32/190 (17%)
		7tmC_GPR158-like	749..998	CDD:320420	74/275 (27%)
		TM helix 1	749..774	CDD:320420	6/32 (19%)
		TM helix 2	786..807	CDD:320420	6/20 (30%)
		TM helix 3	816..840	CDD:320420	11/23 (48%)
		TM helix 4	859..879	CDD:320420	7/19 (37%)
		TM helix 5	901..927	CDD:320420	7/25 (28%)
		TM helix 6	935..958	CDD:320420	7/22 (32%)
		TM helix 7	967..992	CDD:320420	8/24 (33%)