Protein Alignment smog and gpr158a

DIOPT Version :9

• Sequence 1: NP_001245881.1
• Gene: smog / 33690
• FlyBaseID: FBgn0051660
• Length: 951
• Species: Drosophila melanogaster
• Sequence 2: XP_005162591.1
• Gene: gpr158a / 570001
• ZFINID: ZDB-GENE-060130-18
• Length: 1364
• Species: Danio rerio
• Alignment Length: 652
• Identity: 183/652 - (28%)
• Similarity: 276/652 - (42%)
• Gaps: 131/652 - (20%)

  Fly   382 TDGTQ-EWGAPFRDC---NLLTRRWLWPFRISFSEHRIK---------VVAAAFIAADEDVCNDG 433
            |:.|| .|.||:.:|   |.:.|   |...:|...:.:|         ||.......|.|:....
Zfish   240 TEKTQIHWSAPYLECENGNFIPR---WLLTLSAGFYGLKPNRNPDFRGVVRVDVSLQDVDIDQCS 301

  Fly   434 LEEVFGRRHGCDRNTTFCLLTENKPAATRDVYTCLCRESYYLPNS-TLQGFR----GDRVE-LSE 492
            .:..|...|.|:..|..||..... ....|.|.|.|:..||.|:. .:.||:    |...| ||.
Zfish   302 ADGWFAGTHRCNITTMECLPVPGH-GFVLDKYKCHCKSGYYHPSRVAVNGFKRKAGGKGTEGLSH 365

  Fly   493 GYD----NYSCIPCPGGCTNCDSNGVCLTFQEEEVLNVDACLRLLVAIVLGACILCCIVLGVIVF 553
            ..|    :..|:||..||:.|..:..|       |...|..||:.|....|.|:|...:..|:::
Zfish   366 NRDVPETSSHCLPCQEGCSFCKDDTPC-------VARGDGALRMAVLSFQGLCMLVDFISMVLLY 423

  Fly   554 RQRKCKAI-ASGMWTVLETILLGIVLLYASVAVHFFPASTERCLLEPWLRELGFITCYGAIILKL 617
            ..|:.|:| |||: .:||.||.|.:|||..|.:.:|..|..||:|..|:|.|||.|.||.:.|||
Zfish   424 HFRRNKSIRASGL-ILLEAILFGALLLYFPVVILYFQPSVFRCILLRWVRLLGFATVYGTVTLKL 487

  Fly   618 YRHLVDFRTRKAHR------W-VLRDVDLLKYLGTMVFAV-----IC-----YMA----AFTASS 661
            ||.|..|.:|.|.|      | |||.:.:: .|..:.||:     :|     ::|    .||...
Zfish   488 YRVLKVFLSRTAQRIPYMTSWRVLRLLCII-LLIVLWFAIAWTSAVCQNPNRHLALISVGFTTDG 551

  Fly   662 LDLLESAQLESLREADTNTCHPLKWELVTQTSEMLILCFGLHLSIASRNANTQFRERQFLVTALT 726
            |..              :.|...:|:.:...:|.|.|.:|::|..|.|...:.:.|.:::..|:.
Zfish   552 LQF--------------SMCLLDRWDYMIAVAEFLFLLWGVYLCFAVRTVPSAYHEPRYMAIAVH 602

  Fly   727 LEFLVSSSFYFLRFVYLPEMSPSAILLALFIRSQLTNSFALGLIFVPKLWYQHKQVRSLAYDLSI 791
            .|.::|:.|:.|||...||:.|..:|:..|..:.||.:..|||:.|||..:....:|.   |::
Zfish   603 NELILSAIFHILRFTLAPELHPDWMLMLFFAHTHLTVTVTLGLLLVPKFLFAGTHLRD---DIA- 663

  Fly   792 RLPVDAFKGTSHDAGQRLGGGYAGLCLGDPDIGELTISEMSPEDIRA------------------ 838
               .:|::       ..|..|.:|..|........:...:.|||||.
Zfish   664 ---TEAYE-------DELDMGRSGSYLNSSITSAWSEHSLDPEDIRTPEEMGQLSSINGCGVRSC 718

  Fly   839 ----------ELKRLYTQLEIMKNKTLRQDNPHISKRRGGRKAGHRRF---------SLQKKGSK 884
                      |||:||:||||.|.|.:..:|||:.|:|..:|...|..         ::.::.|:
Zfish   719 DSLWEKRTNEELKKLYSQLEIYKRKKMLANNPHLQKKRSSKKGLGRSLMRRITEIPETMGRQCSR 783

  Fly   885 DKALSAKHRSNKHHQDIEITEAEPSRTPEDSVCSAEGPTDTYAEISGVSHSMLSHSMVSHSVVSH 949
            |.....:|.||  |..|.:....|. .|..||    .|....:..|.|.....|||...| |..|
Zfish   784 DDKDQGEHGSN--HNSICVLRKNPF-DPSHSV----KPAKDESLKSKVFSLKKSHSSYDH-VRDH 840

  Fly   950 SK 951
            |:
Zfish   841 SE 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smog	NP_001245881.1	7tm_3	542..776	CDD:278433	82/255 (32%)
gpr158a	XP_005162591.1	7tm_3	412..651	CDD:278433	81/254 (32%)
		Neuromodulin	1135..1276	CDD:284117

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103956
Panther	1	1.100	-	-	O	PTHR32546
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810