Protein Alignment smog and gpr158b

DIOPT Version :10

• Sequence 1: NP_001245881.1
• Gene: smog / 33690
• FlyBaseID: FBgn0051660
• Length: 951
• Species: Drosophila melanogaster
• Sequence 2: XP_697068.4
• Gene: gpr158b / 568637
• ZFINID: ZDB-GENE-130530-875
• Length: 1286
• Species: Danio rerio
• Alignment Length: 719
• Identity: 184/719 - (25%)
• Similarity: 292/719 - (40%)
• Gaps: 166/719 - (23%)

  Fly   342 PSIHTVVVKFR-DNVTIPPDQVHNKAYLGS---YWRELGAA----WNSTDGTQEWGAPFRDCNLL 398
            |.||..||.|. ::...|..||..:|..|.   ..::|...    ..:.....:|...|||.|..
Zfish   172 PKIHRAVVTFHMESPEAPGPQVFLQATRGEERIVLQDLSTTARHRLKNRTSESDWYNVFRDRNKH 236

  Fly   399 TR---------------------RWLWPF----RISFSEHRIKVVAAAFIA-------------- 424
            .|                     :|..|:    ...|..|.:..::|.|..
Zfish   237 KRLVKSRAFPAAHGGYFLDKSHVKWSSPYLECEHGRFVPHWLLTISAGFYGLKNKTAPEFRGVVR 301

  Fly   425 -------ADEDVC-NDGLEEVFGRRHGCDRNTTFCLLTENKPAA----TRDVYTCLCRESYYLPN 477
                   .|.|.| |.|.   |...|.|:..:..|     .|..    ..|.|.|.|:..:|.|:
Zfish   302 VDVNLQDVDIDQCSNSGW---FAGTHRCNLTSMEC-----NPIVGHGFVLDKYKCQCKRGFYHPS 358

  Fly   478 S-TLQGFRGDRVELSEGYDNYS------CIPCPGGCTNCDSNGVCLTFQEEEVLNVDACLRLLVA 535
            . .|.||  .:.:|.. |.:.|      |:||..||..|..:..||..:       |..|||.:.
Zfish   359 RVALNGF--SKTDLGT-YTDESWELSGRCLPCREGCEFCRDDTPCLAHE-------DTALRLAMV 413

  Fly   536 IVLGACILCCIVLGVIVFRQRKCKAI-ASGMWTVLETILLGIVLLYASVAVHFFPASTERCLLEP 599
            ...|.|:|...:..|:|:..|..|.| |||: .:||.||.|.||||..|.:.:...|..||:|..
Zfish   414 SFQGFCMLLDFISMVVVYHFRHNKRIKASGL-ILLEAILSGSVLLYFPVMIQYLNPSVFRCILLR 477

  Fly   600 WLRELGFITCYGAIILKLYRHLVDFRTRKAHR------WVLRDVDLLKYLGTMVFAVICYMAAFT 658
            |:|.|||...||.:||||||.|..|.:|.|.|      |     .:|:.|..::..|:.::||:|
Zfish   478 WVRLLGFAIVYGTVILKLYRVLKVFLSRTAQRIPYMTSW-----RVLRLLAVILLVVMWFLAAWT 537

  Fly   659 ASSLDLLESAQLESLREADTNTCHPL------------------KWELVTQTSEMLILCFGLHLS 705
            ::...             :.||.|.|                  .|:.:...:|.|.|.:|::|.
Zfish   538 SAVCQ-------------NHNTRHALIDIGVTPEGLQFSMCLLDSWDYMMAAAEFLFLLWGVYLC 589

  Fly   706 IASRNANTQFRERQFLVTALTLEFLVSSSFYFLRFVYLPEMSPSAILLALFIRSQLTNSFALGLI 770
            .|.|...:.|.|.::|..|:..|.|:|:.|:.:||.....:.|..:|:..|:.:.||.:..|||:
Zfish   590 YAVRTVPSAFHEPRYLAVAIYNELLISAIFHIIRFSLGTGLHPDWMLMLFFVHTHLTVTVTLGLL 654

  Fly   771 FVPKLWYQHKQVRSLAYDLSIRLPVDAFKGTSHDAGQRLGGGYAGLCLGDPDIGELTISEMSPED 835
            .:||..:.....|.   |::    .:|::       ..|..|::|.||........:...:.|||
Zfish   655 LIPKFLFTGTHARE---DIA----TEAYE-------DELDMGHSGSCLNSSITSAWSEHSLDPED 705

  Fly   836 IRAELKRLYTQLEIMKNKTLRQDNPHISKRRGGRKAGHRRF---------SLQKKGSKDKALSAK 891
            ||.|||:||:||||.|.|.:..:|||:.|:|..::...|..         ::.::.|::....:.
Zfish   706 IREELKKLYSQLEIYKRKKMLANNPHLQKKRSSKRGLGRTLMRRITEIPETVSRQYSREDRDGSD 770

  Fly   892 HRSNKHHQDIEITEAEPS---RTPEDSVCSA----------EGPTDTYAEISGVSHSMLSHSMVS 943
            |.||:  ..:.....:||   ::.|:|:.|.          :...|...:.:||....:.:|...
Zfish   771 HGSNR--STLRRNPFDPSHSGKSREESLKSKMFSLKRSHSYDHTHDQGGQTNGVPGDKMENSTTE 833

  Fly   944 HSVV 947
            .|::
Zfish   834 ASLL 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smog	NP_001245881.1	7tmC_GPR158-like	529..780	CDD:320420	85/275 (31%)
		TM helix 1	529..554	CDD:320420	8/24 (33%)
		TM helix 2	566..587	CDD:320420	10/20 (50%)
		TM helix 3	596..620	CDD:320420	13/23 (57%)
		TM helix 4	639..659	CDD:320420	5/19 (26%)
		TM helix 5	683..709	CDD:320420	8/43 (19%)
		TM helix 6	717..740	CDD:320420	7/22 (32%)
		TM helix 7	749..774	CDD:320420	7/24 (29%)
gpr158b	XP_697068.4	7tmC_GPR158-like	407..663	CDD:320420	85/274 (31%)
		TM helix 1	407..432	CDD:320420	8/24 (33%)
		TM helix 2	444..465	CDD:320420	10/21 (48%)
		TM helix 3	474..498	CDD:320420	13/23 (57%)
		TM helix 4	518..538	CDD:320420	5/19 (26%)
		TM helix 5	567..593	CDD:320420	7/25 (28%)
		TM helix 6	601..624	CDD:320420	7/22 (32%)
		TM helix 7	633..658	CDD:320420	7/24 (29%)