Protein Alignment smog and smog

DIOPT Version :10

• Sequence 1: NP_001245881.1
• Gene: smog / 33690
• FlyBaseID: FBgn0051660
• Length: 951
• Species: Drosophila melanogaster
• Sequence 2: XP_061515357.1
• Gene: smog / 1279347
• VectorBaseID: AGAMI1_012212
• Length: 776
• Species: Anopheles gambiae
• Alignment Length: 847
• Identity: 437/847 - (51%)
• Similarity: 555/847 - (65%)
• Gaps: 128/847 - (15%)

  Fly   130 LLVLLIVGLATATASPSPSPS---HAPFGRESRRDALLAYYKRAHLPQSSSSGISLGHKYHLLHD 191
            ||..|:.|   ..:.|:.|||   |.              |:..|:.:    .:.:|....|::.
Mosquito    16 LLARLVFG---TVSRPTSSPSQQYHC--------------YRHRHILR----WVLVGLISFLINT 59

  Fly   192 ANGL-----------DFDELTPTASSVSALSRAERFRLRKRSATPTTPATAAGVTSLDVATAAAA 245
            .:||           |...:.||.||.|             :.|||.|
Mosquito    60 GHGLEQLSGQQEPQADQQPIPPTFSSTS-------------TPTPTLP----------------- 94

  Fly   246 ATDAAAKDAGSGKKPEEKCEPKVLETLPDEPFYDYTDIAEDAARQFIEFLSGKFPNANTPIAIDE 310
                             .||.:.|:.:|.:||||.:||...||:.|.:||:.:        .||.
Mosquito    95 -----------------PCEQRALDDIPPDPFYDVSDITISAAKSFADFLASR--------KIDG 134

  Fly   311 PTR-----AEVSRRANGIASYALNEDDN-LLAFAIAAPSIHTVVVKFRDNVTIPPDQVH-----N 364
            .:|     |....:||.:|:..|.:||. |||..||.|.:...||:|||.:    |..|     :
Mosquito   135 TSRDDRKFALAREKANELATSVLKQDDGLLLAVGIAYPRLPLAVVQFRDQI----DSAHVNLSES 195

  Fly   365 KAYLGSYWRELGAAWNSTDGTQEWGAPFRDCNLLTRRWLWPFRISFSEHRIKVVAAAFIAADEDV 429
            |.:|.:||||||||||.::|.|.||||||||..|..|||||:.::.....:|:||:||||||.|.
Mosquito   196 KNFLSTYWRELGAAWNQSNGAQFWGAPFRDCGPLYGRWLWPYSVTVESQGVKIVASAFIAADVDQ 260

  Fly   430 CNDGLEEVFGRRHGCDRNTTFCLLTENKPAATRDVYTCLCRESYYLPNSTLQGFRGDRVELSEG- 493
            |||.||.:|||||.|||.:|||||:|...:..|..|||:||..||:||.::|||..::   .:|
Mosquito   261 CNDALESIFGRRHVCDRESTFCLLSELDASKPRGKYTCVCRPGYYIPNESIQGFSSEK---DDGN 322

  Fly   494 YDNYSCIPCPGGCTNCDSNGVCLTFQEEEVLNVDACLRLLVAIVLGACILCCIVLGVIVFRQRKC 558
            ..|:||||||..| .|||.|.|.:  .:|..:.:..::..:..:||||:|||:||.:||||||||
Mosquito   323 ITNFSCIPCPSAC-ECDSEGSCSS--PDEDFSTETLMKATIGAILGACMLCCLVLALIVFRQRKC 384

  Fly   559 KAIASGMWTVLETILLGIVLLYASVAVHFFPASTERCLLEPWLRELGFITCYGAIILKLYRHLVD 623
            |.||:||||:|||||.||:|||.:||:||..|||.|||||||.||||||.|||||:||||||||:
Mosquito   385 KTIATGMWTILETILFGILLLYLAVALHFLQASTVRCLLEPWCRELGFIICYGAIVLKLYRHLVE 449

  Fly   624 FRTRKAHRWVLRDVDLLKYLGTMVFAVICYMAAFTASSLDLLESAQL-------ESL--READTN 679
            ||||||||||:||:|||:||..|:.||:||:|||||:|||.|:.::|       :|:  .:..:|
Mosquito   450 FRTRKAHRWVVRDLDLLRYLCAMIVAVLCYLAAFTATSLDFLQYSELVWQMDQPQSMDAEQVASN 514

  Fly   680 TCHPLKWELVTQTSEMLILCFGLHLSIASRNANTQFRERQFLVTALTLEFLVSSSFYFLRFVYLP 744
            .|.||:|:.||:..|:|||.|||.|:|||||||||||||||||.::.:||||||:||.|||.||.
Mosquito   515 MCRPLRWDYVTEAGELLILGFGLQLAIASRNANTQFRERQFLVASILIEFLVSSTFYILRFWYLE 579

  Fly   745 EMSPSAILLALFIRSQLTNSFALGLIFVPKLWYQHKQVRSLAYDLSIRLPVDAFKGTSHDAGQRL 809
            |.:||.:.||||:||||||:..|||||:||||||||||||||:|:|.||||||||| :|::....
Mosquito   580 EFNPSTLFLALFVRSQLTNTVTLGLIFLPKLWYQHKQVRSLAHDVSFRLPVDAFKG-AHESTHHG 643

  Fly   810 G--GGYAGLCLGDPDIGELTISEMSPEDIRAELKRLYTQLEIMKNKTLRQDNPHISKRRGGRKAG 872
            |  |.|||:|:|||::|::||||||||||||||||||||||.:||||||||||||||||||||..
Mosquito   644 GALGTYAGICMGDPEVGDVTISEMSPEDIRAELKRLYTQLEYLKNKTLRQDNPHISKRRGGRKVA 708

  Fly   873 HRRFSLQKKGSKDKALSAKHRSNKHH-QDIEITEAEPSRTPEDSVCSAEGPTDT---YAEISGVS 933
            |||||||||||::||||||||.|:.. .::|:|||||||||||||||.||||||   ..||||:|
Mosquito   709 HRRFSLQKKGSREKALSAKHRHNRPAVSEVEVTEAEPSRTPEDSVCSVEGPTDTGTGTGEISGIS 773

  Fly   934 HS 935
            .|
Mosquito   774 SS 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smog	NP_001245881.1	7tmC_GPR158-like	529..780	CDD:320420	169/259 (65%)
		TM helix 1	529..554	CDD:320420	11/24 (46%)
		TM helix 2	566..587	CDD:320420	14/20 (70%)
		TM helix 3	596..620	CDD:320420	20/23 (87%)
		TM helix 4	639..659	CDD:320420	12/19 (63%)
		TM helix 5	683..709	CDD:320420	15/25 (60%)
		TM helix 6	717..740	CDD:320420	15/22 (68%)
		TM helix 7	749..774	CDD:320420	16/24 (67%)
smog	XP_061515357.1	None