Protein Alignment smog and LOC1276821

DIOPT Version :10

• Sequence 1: NP_001245881.1
• Gene: smog / 33690
• FlyBaseID: FBgn0051660
• Length: 951
• Species: Drosophila melanogaster
• Sequence 2: XP_061500335.1
• Gene: LOC1276821 / 1276821
• VectorBaseID: AGAMI1_012345
• Length: 1685
• Species: Anopheles gambiae
• Alignment Length: 1054
• Identity: 233/1054 - (22%)
• Similarity: 358/1054 - (33%)
• Gaps: 380/1054 - (36%)

  Fly    36 KCHQNQTNTQVQSTQRSNCSSHSDRDHLTNQQKQQNQRTNSATAASAAAATLSESTRCNIIISSS 100
            |.|.|....:::...       |.||       .|..|.::.....:..||:..|.|.....|||
Mosquito   166 KAHHNLDEVKIELVP-------SFRD-------TQAVRKHAGKRIPSDTATIDSSNRAEEQSSSS 216

  Fly   101 SSSSSST------------------------KSSKNI-REPSSSSSTQLNTLYSL-------LVL 133
            |||||:.                        ..:|:: |.||:..|.....|.||       |:|
Mosquito   217 SSSSSAITVPMSSGAAAGRKPALPWAVEDVGPVAKSVQRSPSAQVSASNQRLISLDAIPRNPLLL 281

  Fly   134 LIVGLATATASPS--PSPSHAPFGRESRRDALLAYYKRAHLPQSSSSGISLGHKYHLLHDANGLD 196
            |..|   :|.||.  .:...:|:  |..|.:.:.                          ::|:|
Mosquito   282 LSPG---STQSPGVMDADHRSPY--EWHRGSRVV--------------------------SDGVD 315

  Fly   197 FDELTPTASSVSALSRAERFRLRKRSATPTTPATAAGVTSLDVATAAAAATDAAAKDAGSGKKPE 261
            :....|.|                                 |.|.|||..|..||.|     :.|
Mosquito   316 YPNDMPVA---------------------------------DAAAAAAVDTGNAADD-----ERE 342

  Fly   262 EKCEPKVLET---------LPDEP----------------------FY-DYTDIAE--------- 285
            ::.|..|.::         |..||                      |: :..|::|
Mosquito   343 QEAEGDVDDSDGLLQDDDPLLQEPELEQEQEEAPAEAPDAADINNVFHMEEADLSELDETSRNNR 407

  Fly   286 -------DAARQFIEF-----LSGKFPNANTPIAIDE-----------PTRAEVS-RRANGI--- 323
                   |...||::.     |.|....|.|.:.:.|           ...||:: .|||.:
Mosquito   408 RNLMKGRDVVTQFLQIVESQHLLGANCTAGTALNLGEGVVDRYAQDRFRVEAEIAVNRANMLTRI 472

  Fly   324 ---ASYALNEDDNLLAFAIAAPSIHTVVVKFRDNVTI-------------------------PPD 360
               :|..:...::||..::.:      :|:|.|::..                         |||
Mosquito   473 FKFSSADVQASEHLLHASVLS------MVEFDDDIFAGGNCFDWNQHPAKRGLFCPFAYRLPPPD 531

  Fly   361 Q----VHNKA----YLGS---------------------YWRELGAAWNST-------------D 383
            |    |.:.|    |||:                     |.:......|:|             |
Mosquito   532 QGASLVKDLALEYHYLGNTSEWFFLARKNAEKVIARNEQYIKSFHVYTNNTERQADEILSVKYED 596

  Fly   384 GTQEWGAPFRDC---NLLTRRWLWPFRISF-----SEHRIKVVAAAFI---AADEDVC-----ND 432
            |  .|..|:.||   |:    |:..:.:.|     ..:..|..:...|   ..|.|.|     ..
Mosquito   597 G--RWSKPYYDCGGGNI----WMLTYTVPFFGYENGTYFFKGTSGIDIDLRRVDIDQCPQKNSPS 655

  Fly   433 GLEE---VFGRRHGCDRNTTFCLLTENKP----AATRDVYTCLCRESYYLPNSTLQG--FRGDRV 488
            |..:   :|.....|.:.||.|     .|    ...|..|.|:||:.||.|::|::.  |.|..:
Mosquito   656 GAPQPLNIFAGTDKCKQRTTEC-----TPIPGLGFRRGSYRCICRKGYYFPDTTIEQKYFNGSTL 715

  Fly   489 ELSEGYD--------------NYSCIPCPGGCTNCDSNGVCLTFQEEEVLNVDACLRLLVAIVLG 539
            |  |.|:              :|.|:||..||..|:....|:.     .||......:||
Mosquito   716 E--EEYEKLMLNEYSTYSIPNSYECLPCAEGCDYCEDASPCVA-----ALNWPMRTSILV----- 768

  Fly   540 ACILCCIVLG------VIVFRQRKCKAIASGMWTVLETILLGIVLLYASVAVHFFPASTERCLLE 598
               |.|.|:|      |..|:.::.|.:.:....:|..|.||...:|.:..|.:.|.|...|...
Mosquito   769 ---LACAVIGLLPPAAVFTFKYQQVKVVRAASPALLRVIALGAFCIYCTSVVMYPPPSLYSCTAR 830

  Fly   599 PWLRELGFITCYGAIILKLYRHLVDFRTRKAHRWVLRDVDLLKYLGTMVFAVICYMAAFTASSLD 663
            .||||:||...|||::||.:|..|.||.|.|....:.|..|||.:|     |:|...........
Mosquito   831 IWLREIGFSLTYGALMLKTWRISVIFRVRSAKAVKITDAYLLKRIG-----VLCGFVGIALLVRT 890

  Fly   664 LLESAQLESLREAD---TNTCHPLKWELVTQTSEMLILCFGLHLSIASRNANTQFRERQFLVTAL 725
            |:....:...|.||   ...|....|:....:.|:|.|.:|:.|.|..|.|.::|.|.:|:..|:
Mosquito   891 LVAPPVVIVGRTADNLKAFLCKTDWWDHTFTSLEVLFLAWGVRLCIMVRKAPSEFNESRFISMAI 955

  Fly   726 TLEFLVSS----SFYFLRFVYLPEMSPSAILLALFIRSQLTNSFALGLIFVPKLWY------QHK 780
            ..|||::.    |..||:    ...:|..:.:..|..:|||.:..|.|||..|::.      :|:
Mosquito   956 YNEFLLTCFLNVSMLFLQ----SPANPDLLYIIFFCHTQLTVTLLLALIFGSKVYLVFRGGGKHQ 1016

  Fly   781 QVRSLAYDLSIRLPVDAFKGTSH-----------DAGQRLGGGYAGLCLGDPDIGELTISEMSPE 834
            ...:   .|.|:.....|...||           .:..:||...|       :.|.||.:|
Mosquito  1017 DDPT---GLGIKPSGAKFISRSHGRTFANASSVTTSTAQLGANMA-------NEGRLTETE---- 1067

  Fly   835 DIRAELKRLYTQLE 848
             ...|||.|||||:
Mosquito  1068 -ALEELKLLYTQLQ 1080

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
smog	NP_001245881.1	7tmC_GPR158-like	529..780	CDD:320420	76/269 (28%)
		TM helix 1	529..554	CDD:320420	7/30 (23%)
		TM helix 2	566..587	CDD:320420	6/20 (30%)
		TM helix 3	596..620	CDD:320420	11/23 (48%)
		TM helix 4	639..659	CDD:320420	6/19 (32%)
		TM helix 5	683..709	CDD:320420	7/25 (28%)
		TM helix 6	717..740	CDD:320420	9/26 (35%)
		TM helix 7	749..774	CDD:320420	8/24 (33%)
LOC1276821	XP_061500335.1	None