DRSC/TRiP Functional Genomics Resources

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Protein Alignment smog and LOC1275493

DIOPT Version :10

Sequence 1:NP_001245881.1 Gene:smog / 33690 FlyBaseID:FBgn0051660 Length:951 Species:Drosophila melanogaster
Sequence 2:XP_061516517.1 Gene:LOC1275493 / 1275493 VectorBaseID:AGAMI1_006749 Length:893 Species:Anopheles gambiae


Alignment Length:940 Identity:188/940 - (20%)
Similarity:316/940 - (33%) Gaps:276/940 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   137 GLATATASPSPSPSHAPFGRESRRDALLAYYKRAHLPQSSSSGISLGHKYHLLHDANGLDFDELT 201
            |...|...|:.......||     .|....|...|....:...|.  .....:||.         
Mosquito    61 GAGAAAGGPNLLEQDGMFG-----PATTTIYTERHTITPTEEAIE--DSLQTIHDI--------- 109

  Fly   202 PTASSVSALSRAERFRLRKRSATPTTPATAAGVTSLDVATAAAAATDAAA---KDAGSGKKPEEK 263
             ...::.||...:.:|..|.:..|            :..|.|....|.||   :|.|..:     
Mosquito   110 -ATENLGALCLTKLYRPLKITLNP------------ERYTGARQKADLAAVVLQDVGVSR----- 156

  Fly   264 CEPKVLETLPDEPFYD-YTDIAEDAARQFIEFLSGKFPNA----NTPIAIDEPTRAEVSRRANGI 323
             ...:|:.|......| |...|...:   |....|...|:    ..|..:..|.|.|    |.||
Mosquito   157 -HNGLLDALAKGLLSDTYVTSARILS---INVTDGLLTNSVWWNKEPGGMGAPLRIE----AEGI 213

  Fly   324 A-------SYALNEDDNLLAFAIAAPSIHTVVVKFRDNVTIPPDQVHNKAYLGSYWRELGAAWNS 381
            |       ||...||:.      ::|.:.:  .||   ...|||    .:|.|         |  
Mosquito   214 AIGTKPDPSYPWFEDET------SSPGLRS--PKF---TPTPPD----ISYKG---------W-- 252

  Fly   382 TDGTQEWGAPFRDCNLLTRRWLWPFRIS---FSEHRIKVVAAAFIAADEDV-------CND---- 432
                  |..|:..|.  .::|:..:.::   ...|.|:    .|::.|.|:       ||:    
Mosquito   253 ------WTYPYYSCG--QKKWILSYSVAIPPMGRHGIR----GFLSIDIDISDLQVNQCNNPNRF 305

  Fly   433 ---------------------GLE------EVFGRRHGCDRNTTFCLLTENKPAA---------- 460
                                 |.:      |.|...|.|..::..|   |.:|..          
Mosquito   306 EILSYNQHLRQYYPFVRNLKLGEDEQMRQIEAFHGSHKCHVHSMRC---EYRPVVTSVISPASLT 367

  Fly   461 ----------------------------------------TRDVYTCLCRESYYL---PNSTLQG 482
                                                    ||..|.|.|::.:|.   |:    |
Mosquito   368 VGPNGTGPLMPLGGSIVNGSGGPSVLLTGGTTLQTVVNGWTRGAYQCRCKDGFYSFRHPD----G 428

  Fly   483 FRGDRVELS--EGYDNYS--------CIPCPGGCTNCDSNGVCLTFQEEEVLNVDACLRLLVAIV 537
            |.|..:|::  |..||.|        |:.|..||..|.....||.       :.:...|..:...
Mosquito   429 FNGSIMEVAYQEYRDNISTYYKEVFVCVRCAPGCATCTGPEPCLA-------SYNWAFRTTLLTF 486

  Fly   538 LGACILCCIVLGVIVFRQRKCKAIASGMWTVLETILLGIVLLYASVAVHFFPASTERCLLEPWLR 602
            ...|....:||.:.:::.||.|.........|...|||...:|..:|..|....|..|:...|.|
Mosquito   487 SVMCAGFTVVLALYMYQHRKVKVFKVASPIFLTITLLGCAFMYLEMAAIFPILDTYSCIATKWTR 551

  Fly   603 ELGFITCYGAIILKLYRHLVDFRTRKAHRWVLRDVDLLKYLGTMVFAVICYMAAFTASSLDLLES 667
            .:||...|.|:::|.:|..:.:|.:.||:..|.|..||:::..::..:..|:..:|.|:....| 
Mosquito   552 HMGFCVTYTALLMKTWRVSLTYRVKSAHKVKLTDKQLLQWMVPILLVMFIYLGTWTLSAPPTAE- 615

  Fly   668 AQLESLREADTNTCHPLKWELVTQTSEMLILCFGLHLSIASRNANTQFRERQFLVTALTLEFLVS 732
             ::|.........|....|:......|:|.|.:|:.:....|||.:.:.|.:.:..|:....||:
Mosquito   616 -RIEDQYGLIFKQCSYNWWDHSLAIGEVLFLAWGIRVCYNVRNAESLYNEAKLISYAIYNIALVN 679

  Fly   733 SSFYFLRFVYLPEMSPSAILLALFIRSQLTNSFALGLIFVPKL----------WYQHKQVRSLAY 787
            ::.........|:..|....|..|||:||:.|..:.|:|.||:          |.|..:.|.:..
Mosquito   680 TTMVAFHLFIFPQAGPDIKYLLGFIRTQLSTSVTIALVFGPKVLRILRGQGDQWDQRARKRGITA 744

  Fly   788 DLSIRLPVDAFKGTSHDAGQRLGGGYAGLCLGDPDIGELTISEMSPEDIRAELKRLYTQLEIMKN 852
            ..|:.                      |:.|...:..:|   ....|:::.|:::|..|:|.||.
Mosquito   745 SFSLN----------------------GIGLVPEETADL---YQENEELKEEIQKLAAQIEFMKI 784

  Fly   853 KTLRQDNPHISKRRGGRKAGHRRFSLQKK-----------GSKDKALSAKHRSNKHHQDIEITEA 906
            ..:..:|.|:..:.||      .|:::..           |:...:.|..|| :||.:|..:   
Mosquito   785 VHMEMNNRHLKPKPGG------YFTMKSPLGKSFGGGAGGGAGGGSGSGSHR-HKHTKDDSV--- 839

  Fly   907 EPSRTPEDSVCSAEGPTDTYAEISGVSHSM 936
                 .|.|..:.:|.:.|.:..||.::|:
Mosquito   840 -----KEHSGVTEDGHSGTNSCYSGTANSI 864

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
smogNP_001245881.1 7tmC_GPR158-like 529..780 CDD:320420 64/260 (25%)
TM helix 1 529..554 CDD:320420 4/24 (17%)
TM helix 2 566..587 CDD:320420 6/20 (30%)
TM helix 3 596..620 CDD:320420 7/23 (30%)
TM helix 4 639..659 CDD:320420 3/19 (16%)
TM helix 5 683..709 CDD:320420 5/25 (20%)
TM helix 6 717..740 CDD:320420 4/22 (18%)
TM helix 7 749..774 CDD:320420 9/24 (38%)
LOC1275493XP_061516517.1 None

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