DRSC/TRiP Functional Genomics Resources

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Protein Alignment smog and gpr179

DIOPT Version :10

Sequence 1:NP_001245881.1 Gene:smog / 33690 FlyBaseID:FBgn0051660 Length:951 Species:Drosophila melanogaster
Sequence 2:XP_031750226.1 Gene:gpr179 / 100496332 XenbaseID:XB-GENE-994077 Length:1546 Species:Xenopus tropicalis


Alignment Length:1026 Identity:235/1026 - (22%)
Similarity:391/1026 - (38%) Gaps:304/1026 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    74 TNSATAASAAAATLSESTRCNIIISS-SSSSSSSTKSSKNIREPSSSSSTQLNTLYSLLVLLIVG 137
            |..:|.:....:|...|...::.:|: :.::|||.:|:.::....|:|||              .
 Frog    40 TPLSTTSPGLPSTSFPSAVSSLAVSAPADTASSSPESTSSLPFSPSTSST--------------S 90

  Fly   138 LATATASPSPSPSHAPFGRESRRDALLAYYKRAHLPQSSSSGISLGHKYHLLHDANGLDFDELT- 201
            .:..|.:|||....|  ..|..:.||...:...||               ||.:||.....||| 
 Frog    91 FSVTTLAPSPDVDKA--DEEGSKAALNFLHSGDHL---------------LLSEANCSKSFELTD 138

  Fly   202 ----PTASSVS-------ALSRAERFRLRKRSATPTTPATAAGVTSLDVATAAAAATDAAAKDAG 255
                |..:.:|       :|..|..|                    |::...|:...:::.|:  
 Frog   139 LQGPPPETLLSHIRGPQDSLLHATNF--------------------LNMIFQASDMRESSIKE-- 181

  Fly   256 SGKKPEEKCEPKVLETLPDEPFYDYTDIAEDAARQFIEFLSGKFPNANTPIAIDEPTRAEVSRRA 320
                              |..:|          ...:..|:|..||..         ||.:|..|
 Frog   182 ------------------DMEWY----------HALVRSLAGGQPNIR---------RALLSLTA 209

  Fly   321 NGIASYALNEDDNLLAFAIAAPSIHTVVVKFRDNVTIPPDQVH--NKAYLGSYWRELGAA----- 378
            :.::|       ..|....|....|.::::     .:..|..|  :|...|| |....|:     
 Frog   210 HPMSS-------KPLLLLRATKKGHEILLQ-----DLSSDFYHGRHKGNWGS-WDNFHASSSLTK 261

  Fly   379 --------------WNSTD------GTQEWGAPFRDC---NLLTRRWLWPFRISFSEHRIKV-VA 419
                          |:..|      ....|..||.:|   :.|..   |...:|.:.:.:|. ::
 Frog   262 AILLNDLRSLDTPKWSRGDSYIVDLSHVRWSKPFLECEGGHFLQG---WMISLSTAFYGLKPDLS 323

  Fly   420 AAF---IAADEDVCNDGLEEV------FGRRHGCDRNTTFCLLTENKPAATRDVYTCLCRESYYL 475
            ..|   :..|..:.|.|:::.      |...|.||.|:|.| :::.|..:....|.|:|:..||.
 Frog   324 PEFKGTLRVDVQLLNLGIDQCAKGPGWFANSHSCDENSTQC-ISDEKDGSILGRYRCVCQPGYYR 387

  Fly   476 PNSTLQGFRGDRVELSEGYDNYSCIPCPGGCTNCDSNGVCLTFQEEEVLNVDACLRLLVAIVLGA 540
            .       |.:..|:|    |.:|.||..||..|.....||       ::.|..||:.|..|...
 Frog   388 T-------RHEGSEIS----NVACRPCSEGCATCVDGSPCL-------VDEDWALRVTVLSVQAT 434

  Fly   541 CILCCIVLGVIVFRQRKCKAI-ASGMWTVLETILLGIVLLYASVAVHFFPASTERCLLEPWLREL 604
            .:|...:..::.:..|..|.| |||: .:|||||.|.:|||..|.:.:|..|..||:...|:|.|
 Frog   435 GMLAVFLSMLVSYSFRDSKRIRASGL-ILLETILFGSLLLYFPVFILYFKPSVFRCVALRWVRLL 498

  Fly   605 GFITCYGAIILKLYRHLVDFRTRKAHRW-VLRDVDLLKYLGTMVFAVIC--YMAAFTASSLDLLE 666
            ||...||.|:|||||.:..|.:|.|.|. .|..:.||:.|  .||.:.|  ::..:|..:|:.|:
 Frog   499 GFCIVYGTIVLKLYRVMKVFLSRTAQRVPYLTSMRLLRML--FVFLLFCIWFLVGWTVGALENLQ 561

  Fly   667 SAQLESLREADTN-----TCHPLKWELVTQTSEMLILCFGLHLSIASRNANTQFRERQFLVTALT 726
            ......:|.....     ||...:|:.:...:|:|.||:|..|...:|:..:.|.|.:::..|:.
 Frog   562 RGVPVVIRTQTREGLVFYTCDHDRWDYMMSIAEVLFLCWGSFLCYGARSIPSAFHEPRYMGIAIH 626

  Fly   727 LEFLVSSSFYFLRFVYLPEMSPSAILLALFIRSQLTNSFALGLIFVPKLWY----QHKQVRSLAY 787
            .|.:||::|:.|||:.:|.:.|...||..||.:..|.:..|.|:|:||..:    ..:::.:..|
 Frog   627 NEMIVSAAFHVLRFLIVPSLHPDWTLLLFFIHTHGTVTMTLTLLFIPKFLHAGVPPREEIATEVY 691

  Fly   788 DLSIRLPVDAFKGTSHDAGQRLGGGYAGLCLGDPDIGELTISEMSPEDIRAELKRLYTQLEIMKN 852
            :..:    |..:..|:              |........:...:.|:|||.|||:||.|||:.|.
 Frog   692 EDEL----DMRRSRSN--------------LNSSITSAWSEHSLDPDDIRDELKKLYAQLEVHKT 738

  Fly   853 KTLRQDNPHISKRRGGRK--------------------------------AGHRRFSLQKKGS-- 883
            |.:..:|||:.|:|..|:                                :|.:|...|..||  
 Frog   739 KKMTINNPHLQKKRSSRRGLGRSIMRRITETPDSANRQSTREDKEGSPGSSGGQRRKQQDSGSVK 803

  Fly   884 ------KDKALSAK--HRSNKHHQDI---------EITEAEPS----------------RTPEDS 915
                  :.:.||.:  |.:..|.|:.         |.:..:||                |:..||
 Frog   804 QREESLRQRVLSLRKSHSTYDHMQECKDAGPPSPRESSTRDPSLRDSVMRRNLARNVSMRSRGDS 868

  Fly   916 VCSAEGPTDTYAEISGVSHSMLSHSMV---------------SHSVVSHSK 951
            :|.|  |.        |..|:.:|:::               ||||:...|
 Frog   869 LCHA--PL--------VCKSLSAHNLLADKKPLSVRPGPLQKSHSVMGSGK 909

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
smogNP_001245881.1 7tmC_GPR158-like 529..780 CDD:320420 85/263 (32%)
TM helix 1 529..554 CDD:320420 5/24 (21%)
TM helix 2 566..587 CDD:320420 10/20 (50%)
TM helix 3 596..620 CDD:320420 12/23 (52%)
TM helix 4 639..659 CDD:320420 6/21 (29%)
TM helix 5 683..709 CDD:320420 7/25 (28%)
TM helix 6 717..740 CDD:320420 7/22 (32%)
TM helix 7 749..774 CDD:320420 8/24 (33%)
gpr179XP_031750226.1 PTZ00214 <368..>415 CDD:173479 16/57 (28%)
7tmC_GPR158-like 423..679 CDD:320420 85/258 (33%)
TM helix 1 423..448 CDD:320420 5/24 (21%)
TM helix 2 460..481 CDD:320420 10/21 (48%)
TM helix 3 490..514 CDD:320420 12/23 (52%)
TM helix 4 534..554 CDD:320420 6/21 (29%)
TM helix 5 583..609 CDD:320420 7/25 (28%)
TM helix 6 617..640 CDD:320420 7/22 (32%)
TM helix 7 649..674 CDD:320420 8/24 (33%)

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