Protein Alignment Mon1 and Mon1a

DIOPT Version :9

• Sequence 1: NP_608868.1
• Gene: Mon1 / 33689
• FlyBaseID: FBgn0031640
• Length: 528
• Species: Drosophila melanogaster
• Sequence 2: NP_082645.1
• Gene: Mon1a / 72825
• MGIID: 1920075
• Length: 556
• Species: Mus musculus
• Alignment Length: 535
• Identity: 212/535 - (39%)
• Similarity: 312/535 - (58%)
• Gaps: 48/535 - (8%)

  Fly     2 EVEQTSVRSDTNSTCEYLDAEGDPESPNLYQEADPDQEAEQQNHSIISELRDGL--GTMRDNSAL 64
            |:|......|:...|.   ....|.:.::.|.:....|...|...:..:|::.:  |:..|
Mouse    62 ELEDREASGDSPKECV---GSPPPLATDMRQISQDFSELSTQLTGVARDLQEEMLPGSSED---- 119

  Fly    65 SPEP-GQENKGLAASVESLALSTSTSAKTEDSIGGGLEEEYDYQHDSLWQGQKKHIFILSEAGKP 128
            .||| |...:|               |.||.|..|..|.|.:...:: |:..:||:|:|||||||
Mouse   120 WPEPQGAAGRG---------------AATEPSQEGSTEGEEEDATEA-WRLHQKHVFVLSEAGKP 168

  Fly   129 IFSLHGNEDKLATLFGVIQALVSFVQMGQDAITSIHAGGIKFAFMQRSSLILVAASRSNMSVQQL 193
            ::|.:|:|:.|::..||:.|||||::..::||.||||.|.|..|::||.|:|||.:|:..|.|:|
Mouse   169 VYSRYGSEEALSSTMGVMVALVSFLEADKNAIRSIHADGYKVVFVRRSPLVLVAVARTRQSAQEL 233

  Fly   194 QLQLGDVYNQILSILTYSHMTKIFERRKNFDLRRLLSGSERLFYNLL---ANDSSSAKVSNNIFT 255
            ..:|..:|.||||:||.:.::.||::::|:|||||||||||:..|||   |.|.|
Mouse   234 AQELLYIYYQILSLLTGAQLSHIFQQKQNYDLRRLLSGSERITDNLLQLMARDPS---------- 288

  Fly   256 FLTNSIRVFPLPTTIRSQITSAIQSNCSKIKNLVFAVLIANNKLIALVRMKKYSIHPADLRLIFN 320
            ||..:.|..||...:|..:::::|.  ::.::|||::|:|:|:|:||||.|...:||.||.|:||
Mouse   289 FLMGAARCLPLAAAVRDTVSASLQQ--ARARSLVFSILLAHNQLVALVRRKDQFLHPIDLHLLFN 351

  Fly   321 LVECSESFKSSENWSPICLPKFDMNGYLHAHVSYLADDCQACLLLLSVDRDAFFTLAEAKAKITE 385
            |:..|.||:..|.|:|:|||||...|:.|||:|||..|...||||:|.||:.||.:::.:.:..|
Mouse   352 LISSSSSFREGEAWTPVCLPKFSAAGFFHAHISYLEPDTDLCLLLISTDREDFFAVSDCRRRFQE 416

  Fly   386 KLRKSHCLEAINEELQQPFNAKLYQQV--VGIPELRHFLYKPKSTAQLLCPMLRHPYKSLTELER 448
            :|||.....|:.|.|:.|     |..|  ||||:|||||||.||:.....|.:..||.|..|.||
Mouse   417 RLRKRGTHLALREALRTP-----YYSVAQVGIPDLRHFLYKSKSSGLFTSPEIEAPYSSEEEQER 476

  Fly   449 LEAIYCDLLHRIHNSSRPLKLIYEMKEREVVLAWATGTYELYAIFEPVVDKATVIKYVDKLIKWI 513
            |..:|..|..|.||:|||||.||.....|.:|||.||.:|||..:.|:..||:.:..:.||::||
Mouse   477 LLGLYQYLHSRAHNASRPLKTIYYTGPNENLLAWVTGAFELYMCYSPLGTKASAVSAIHKLMRWI 541

  Fly   514 EKEYDVYFIRNHATF 528
            .||.|..||....|:
Mouse   542 RKEEDRLFILTPLTY 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mon1	NP_608868.1	Mon1	115..527	CDD:281196	187/416 (45%)
Mon1a	NP_082645.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..88		5/28 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	113..149		14/54 (26%)
		Mon1	155..555	CDD:367367	187/416 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836632
Domainoid	1	1.000	361	1.000	Domainoid score	I952
eggNOG	1	0.900	-	-		E1_KOG0997
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7191
Inparanoid	1	1.050	366	1.000	Inparanoid score	I2143
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54491
OrthoDB	1	1.010	-	-		D265654at33208
OrthoFinder	1	1.000	-	-		FOG0002019
OrthoInspector	1	1.000	-	-		otm42775
orthoMCL	1	0.900	-	-		OOG6_102023
Panther	1	1.100	-	-	LDO	PTHR13027
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R732
SonicParanoid	1	1.000	-	-		X1326
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.800