DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpS2 and MRPS2

DIOPT Version :9

Sequence 1:	NP_523473.2	Gene:	mRpS2 / 33688	FlyBaseID:	FBgn0031639	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_001358330.1	Gene:	MRPS2 / 51116	HGNCID:	14495	Length:	296	Species:	Homo sapiens

Alignment Length:	226	Identity:	129/226 - (57%)
Similarity:	159/226 - (70%)	Gaps:	10/226 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 STQPEQSVETEPEDIALVEQRILKHPDYFQVHNLFTVRDLFNARVHYGHKEGSLDDRMRPYLFGS 88
            ||.....:..||          |||.|:|.|..||:||.||:||||.|||.|.....|.||:|||
Human    55 STDFNDKILNEP----------LKHSDFFNVKELFSVRSLFDARVHLGHKAGCRHRFMEPYIFGS 109

  Fly    89 RLGHLIFDLDKTASHLRDALNFAAHIAFRDGIILFFNRNAMNSHLVERKAQEAGEFSHTRFWRGG 153
            ||.|.|.||::||:||:.||||.||:|:|.|||||.:||...|:|:|..|::.||::|||::|||
Human   110 RLDHDIIDLEQTATHLQLALNFTAHMAYRKGIILFISRNRQFSYLIENMARDCGEYAHTRYFRGG 174

  Fly   154 IFTNANVQFDAVTRLPDLCIFLNTQNNVMAQHTAVRDAAKMAIPTIGIVDSNCNPNLITYPVPGN 218
            :.|||.:.|....|||||.|||:|.||:...|.||||||||.|||:||||:||||.|||||||||
Human   175 MLTNARLLFGPTVRLPDLIIFLHTLNNIFEPHVAVRDAAKMNIPTVGIVDTNCNPCLITYPVPGN 239

  Fly   219 DDSPAAVELYCNLFKEAILRGKRERRQLLGL 249
            ||||.||.|||.||:.||.|.|.:|:|:..|
Human   240 DDSPLAVHLYCRLFQTAITRAKEKRQQVEAL 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpS2	NP_523473.2	RPS2	63..238	CDD:100106	110/174 (63%)
MRPS2	NP_001358330.1	RPS2	84..259	CDD:100106	110/174 (63%)
MRPS2	NP_001358330.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	274..296
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152933
Domainoid	1	1.000	121	1.000	Domainoid score	I5734
eggNOG	1	0.900	-	-		E1_COG0052
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H99837
Inparanoid	1	1.050	259	1.000	Inparanoid score	I3127
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62495
OrthoDB	1	1.010	-	-		D437653at33208
OrthoFinder	1	1.000	-	-		FOG0002724
OrthoInspector	1	1.000	-	-		oto88423
orthoMCL	1	0.900	-	-		OOG6_101759
Panther	1	1.100	-	-	LDO	PTHR12534
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1256
SonicParanoid	1	1.000	-	-		X3526
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800