DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpS2 and RPSA

DIOPT Version :9

Sequence 1:	NP_523473.2	Gene:	mRpS2 / 33688	FlyBaseID:	FBgn0031639	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_001291217.1	Gene:	RPSA / 3921	HGNCID:	6502	Length:	300	Species:	Homo sapiens

Alignment Length:	184	Identity:	40/184 - (21%)
Similarity:	70/184 - (38%)	Gaps:	26/184 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 ARVHYGHKEGSLDDRMRPYLFGSRL-GHLIFDLDKTASHLRDALNFAAHIAFRDGIILFFNRN-- 127
            |..|.|..  :||.:|..|::..:. |..|.:|.:|...|..|......|.....:.:..:||
Human    21 AGTHLGGT--NLDFQMEQYIYKRKSDGIYIINLKRTWEKLLLAARAIVAIENPADVSVISSRNTG 83

  Fly   128 --------AMNSHLVERKAQEAGEFSHTRFWRGGIFTNANVQFDAVTRLPDLCIFLNTQNNVMAQ 184
                    .:...........||.|:      .|.|||   |..|..|.|.|.:..:.:    |.
Human    84 QVCGTVRAVLKFAAATGATPIAGRFT------PGTFTN---QIQAAFREPRLLVVTDPR----AD 135

  Fly   185 HTAVRDAAKMAIPTIGIVDSNCNPNLITYPVPGNDDSPAAVELYCNLFKEAILR 238
            |..:.:|:.:.:|||.:.:::.....:...:|.|:....:|.|...:....:||
Human   136 HQPLTEASYVNLPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLAREVLR 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpS2	NP_523473.2	RPS2	63..238	CDD:100106	38/182 (21%)
RPSA	NP_001291217.1	PTZ00254	1..255	CDD:240331	40/184 (22%)
		Laminin-binding	166..185		4/18 (22%)
		Laminin-binding	210..234
		[DE]-W-[ST] 1	235..237
		Laminin-binding	247..300
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	271..300
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810