DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpS2 and Rpsa

DIOPT Version :9

Sequence 1:	NP_523473.2	Gene:	mRpS2 / 33688	FlyBaseID:	FBgn0031639	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_058834.1	Gene:	Rpsa / 29236	RGDID:	71026	Length:	295	Species:	Rattus norvegicus

Alignment Length:	179	Identity:	41/179 - (22%)
Similarity:	73/179 - (40%)	Gaps:	21/179 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 ARVHYGHKEGSLDDRMRPYLFGSRL-GHLIFDLDKTASHLRDALNFAAHIAFRDGIILFFNRNAM 129
            |..|.|..  :||.:|..|::..:. |..|.:|.:|...|..|......|.....:.:..:||..
  Rat    21 AGTHLGGT--NLDFQMEQYIYKRKSDGIYIINLKRTWEKLLLAARAIVAIENPADVSVISSRNTG 83

  Fly   130 NSHLVERKAQE-----AGEFSHTRFWRGGIFTNANVQFDAVTRLPDLCIFLNTQNNVMAQHTAVR 189
            ...:::..|..     ||.|:      .|.|||   |..|..|.|.|.:..:.:    |.|..:.
  Rat    84 QRAVLKFAAATGATPIAGRFT------PGTFTN---QIQAAFREPRLLVVTDPR----ADHQPLT 135

  Fly   190 DAAKMAIPTIGIVDSNCNPNLITYPVPGNDDSPAAVELYCNLFKEAILR 238
            :|:.:.:|||.:.:::.....:...:|.|:....:|.|...:....:||
  Rat   136 EASYVNLPTIALCNTDSPLRYVDIAIPCNNKGAHSVGLMWWMLAREVLR 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpS2	NP_523473.2	RPS2	63..238	CDD:100106	39/177 (22%)
Rpsa	NP_058834.1	PTZ00254	1..250	CDD:240331	41/179 (23%)
		Interaction with PPP1R16B. /evidence=ECO:0000255\|HAMAP-Rule:MF_03016	54..113		15/67 (22%)
		Laminin-binding. /evidence=ECO:0000255\|HAMAP-Rule:MF_03016	161..180		4/18 (22%)
		Laminin-binding. /evidence=ECO:0000255\|HAMAP-Rule:MF_03016	205..229
		[DE]-W-[ST] 1	230..232
		Laminin-binding. /evidence=ECO:0000255\|HAMAP-Rule:MF_03016	242..295
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	266..295
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810