Protein Alignment CG12194 and AQR1

DIOPT Version :9

• Sequence 1: NP_001162873.1
• Gene: CG12194 / 33685
• FlyBaseID: FBgn0031636
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_014334.3
• Gene: AQR1 / 855660
• SGDID: S000005009
• Length: 586
• Species: Saccharomyces cerevisiae
• Alignment Length: 607
• Identity: 118/607 - (19%)
• Similarity: 211/607 - (34%)
• Gaps: 186/607 - (30%)

  Fly     1 MSREERKPIVSSSSSSTCS-SSDDEVHPVVRRRSTRDTE----LAGHQKDAGCCDPTSTPHRFLA 60
            :|:...:.|.....|.|.| ||||:|.|.  ::.|.:|:    |..:.:..|          .:|
Yeast    52 LSKTTTREIEGDLDSETSSHSSDDKVDPT--QQITAETKAPYTLLSYGQKWG----------MVA 104

  Fly    61 LLFMCLLGF----GSYFCYDNPGALQDVFQKELQLSSTEFTLIYSIYSWPNIVLCFVGGFLIDRV 121
            :|.||  ||    ||...|  |...|  .:|:..:......:...:|.....:...|.|.|.| .
Yeast   105 ILTMC--GFWSSLGSPIYY--PALRQ--LEKQFNVDENMVNVTVVVYLLFQGISPTVSGGLAD-C 162

  Fly   122 FGIRLGTIIYMLIVLVGQLIFATGGV----LGHFWLMIVGRFVFGIG-AESLAVAQ---NSYAVL 178
            ||.|       .|:|.|.||:....:    ...:.::|..|.:..|| :.::|::.   ..:.:.
Yeast   163 FGRR-------PIILAGMLIYVIASIGLACAPSYGVIIFLRCIQSIGISPTIAISSGVVGDFTLK 220

  Fly   179 WFKGKEINMVFGLQLSVARFGSTVNFWIMQPLYGYVSKSYSGYKGLGVALFLASSTCVMSLVCTL 243
            ..:|..:....|..|....|||         |.|.|..:...::.:...|.:...:|.  |:..|
Yeast   221 HERGTFVGATSGFVLLGQCFGS---------LIGAVLTARWDWRAIFWFLTIGCGSCF--LIAFL 274

  Fly   244 IL--------GWMDKRAERILKR--------------NNNP----------------GGELAKLS 270
            ||        |.:..:.:|.:.|              .:||                .|::..|.
Yeast   275 ILPETKRTIAGNLSIKPKRFINRAPIFLLGPVRRRFKYDNPDYETLDPTIPKLDLSSAGKILVLP 339

  Fly   271 DIVT------FKLDFWMVSVVCVAYYVAIFPF----VALG------------QAFF--------- 304
            :|:.      .....|.:.:..::..:::.|:    |.:|            .:||
Yeast   340 EIILSLFPSGLLFAMWTLMLSSISSGLSVAPYNYHLVIIGVCYLPGGIGGLMGSFFTGRIIDMYF 404

  Fly   305 ---VSNFHMTPDEAN------------TVNSIVYL----ISAIASPLFGFVIDKVGRNVTWVFCA 350
               :..|..  |:||            .|..:..|    ::.:|..|||:.|||..|
Yeast   405 KRKIKKFEQ--DKANGLIPQDAEINMFKVRLVCLLPQNFLAVVAYLLFGWSIDKGWR-------- 459

  Fly   351 TISTLLAHFLLTFTHLDPYIGMSIMGLSYSMLAASLWPLVSLIVP------EYQLGTAYGFCQSV 409
            ..|.|:..|:.:      |..||.:..|.::| ..|:|..|....      ...|.|.:..|.:.
Yeast   460 IESILITSFVCS------YCAMSTLSTSTTLL-VDLYPTKSSTASSCFNFVRCSLSTIFMGCFAK 517

  Fly   410 QNLGLAVVTIAAGIIVDSSGGSHFWL--QVFFMSFLLVSLLATCAIWAYNRKHQGNLNMSPAQRA 472
            ....:.|            ||:..:|  .|||.:||:...:.....|..:|       :...||.
Yeast   518 MKAAMTV------------GGTFTFLCALVFFFNFLMFIPMKYGMKWREDR-------LLKQQRQ 563

  Fly   473 TYHTSIAMQCRHMNRRPLLGNY 494
            ::..::|::.:...:|....|:
Yeast   564 SWLNTLAVKAKKGTKRDQNDNH 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12194	NP_001162873.1	MFS	61..454	CDD:119392	95/500 (19%)
		MFS_1	64..416	CDD:284993	85/457 (19%)
AQR1	NP_014334.3	MFS_Tpo1_MDR_like	103..553	CDD:340881	96/503 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341816
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930