DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG12194 and ATR2

DIOPT Version :9

Sequence 1:	NP_001162873.1	Gene:	CG12194 / 33685	FlyBaseID:	FBgn0031636	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_014006.1	Gene:	ATR2 / 855322	SGDID:	S000004892	Length:	540	Species:	Saccharomyces cerevisiae

Alignment Length:	505	Identity:	103/505 - (20%)
Similarity:	170/505 - (33%)	Gaps:	150/505 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SREERKPIVSSSSSSTCSSSDDEVHPVVRRRSTRDTELAGHQKDAGCCDPT--STPHRFLALLFM 64
            |..:.|..|.:......|:.|:||..:|  .||:.|::.   .|:...|||  |:..:.|..:..
Yeast    16 SEIDEKITVKAKDKVVVSTEDEEVTTIV--SSTKSTQVT---NDSPWQDPTYFSSFGKELMFIAT 75

  Fly    65 CLL-------GFGSYFCYDNPGALQDVFQKELQLSSTEFTLIYSIYSWPNIVLCF--VGGFLIDR 120
            |:|       |.....|..|  .|...|..|....:      :.:.|:|.....|  :.|.|.|
Yeast    76 CMLAQLLNQAGQTHALCIMN--VLSKSFNSEANNQA------WLMASFPLAAGSFILISGRLGD- 131

  Fly   121 VFGIRLGTIIYMLIVLVGQLIFATGGVLGHFWLMIVGRFVFGIG-----AESLAVAQNSYAVLWF 180
            ::|::...|:..:||:|..:|.............|..|...|:|     ...:.:..:.|.|..|
Yeast   132 IYGLKKMLIVGYVIVIVWSIISGLSKYSNSDAFFITSRAFQGVGIAFILPNIMGLVGHVYKVGSF 196

  Fly   181 KGKEINMVF------------GLQLSVARFGSTV-----NFWIMQPLYGYVSKSYSGYKGLGVAL 228
            : |.|.:.|            ||      ||..:     |.|   |...|         ..|:|.
Yeast   197 R-KNIVISFIGACAPTGGMFGGL------FGGLIVTEDPNQW---PWVFY---------AFGIAT 242

  Fly   229 FLASSTCVMSLVCTLILGWMDKRAERILKRNNNP-----------GGELAKLSDIVTFKLDF--- 279
            ||           :|::.|..       ..||.|           |..|| :..::.|...:
Yeast   243 FL-----------SLLMAWYS-------IPNNVPTNIHGLSMDWTGSALA-IIGLILFNFVWNQA 288

  Fly   280 ----WMVSVVCVAYYVAIFPFVALGQAFFV--SNFHMTP--DEANTVNSIVYLISAIASPLFGFV 336
                |....:.|...:::...|    ||||  |.:...|  ..|.|.|.  ::|..:.:...|:
Yeast   289 PIVGWDKPYIIVLLIISVIFLV----AFFVYESKYAEVPLLPRAMTKNR--HMIMILLAVFLGW- 346

  Fly   337 IDKVGRNVTWVFCATISTLLAHFLLTFTHLDP-------------------YIGMSI--MG---- 376
                |....|.|      ....|.|...|..|                   ::..||  :|
Yeast   347 ----GSFGIWTF------YYVSFQLNLRHYSPVWTGGTYFVFVIFGSMAAFFVAFSIKRLGPALL 401

  Fly   377 LSYSMLAASLWPLVSLIVPEYQLGTAYGFC-QSVQNLGLAVVTIAAGIIV 425
            |.:|::|.....::..::|..|......|. |::...|:.:...|:.||:
Yeast   402 LCFSLMAFDAGSIMFSVLPVEQSYWKLNFAMQAILCFGMDLSFPASSIIL 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12194	NP_001162873.1	MFS	61..454	CDD:119392	86/444 (19%)
CG12194	NP_001162873.1	MFS_1	64..416	CDD:284993	83/430 (19%)
ATR2	NP_014006.1	MFS_Amf1_MDR_like	74..519	CDD:341029	86/442 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341810
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930