Protein Alignment CG12194 and AZR1

DIOPT Version :9

• Sequence 1: NP_001162873.1
• Gene: CG12194 / 33685
• FlyBaseID: FBgn0031636
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_011740.3
• Gene: AZR1 / 853139
• SGDID: S000003456
• Length: 613
• Species: Saccharomyces cerevisiae
• Alignment Length: 627
• Identity: 117/627 - (18%)
• Similarity: 200/627 - (31%)
• Gaps: 236/627 - (37%)

  Fly    28 VVRRRSTRDT--ELAGHQKDAGCCDPTSTPHRF--------LAL-LFMCLLG------------- 68
            ||||.||:.|  :......:....:....|..|        ||| ||:..|.
Yeast    32 VVRRNSTQSTSKQNVSVVLEDNASESNELPKGFILYASLIALALSLFLAALDIMIVSTIIEEVAK 96

  Fly    69 -FGSYFCYDNPGALQDVFQKELQLSSTEFTLIYSIYSWPNIVLCFVGGFLIDRVFGIRLGTIIYM 132
             ||||                     :|...:::.||.||.:|..:.|.:...: |.:...:..:
Yeast    97 QFGSY---------------------SEIGWLFTGYSLPNALLALIWGRIATPI-GFKETMLFAI 139

  Fly   133 LIVLVGQLIFATGGVLGHFWLMIVGRFVFGIGA----------------ES-----LAVAQNSYA 176
            :|..:|.||.|....:.   ::|.||.:.|:|.                ||     :||...|:|
Yeast   140 VIFEIGSLISALANSMS---MLIGGRVIAGVGGCGIQSLSFVIGSTLVEESQRGILIAVLSCSFA 201

  Fly   177 VLWFKGKEINMVFGLQLSVARFGSTVN----FWIMQPLYGYVSKSYSGYKGLGVALFLASSTCVM 237
            :....|..:..|         |.|:|.    |::..|:.|.....:..:...|::.|..:...:.
Yeast   202 IASVVGPFLGGV---------FTSSVTWRWCFYVNLPIGGLAFFLFLFFYNPGLSTFQETMDNIR 257

  Fly   238 SLVCTLI-----LGWMDKRAERILKRN--NNPGGELAKLSDIVTFK------------------- 276
            ......|     :.:...:.:...|.|  ..|..||..:.||:.|.
Yeast   258 KFPSQFIEIVRNVAYHLLKIKGFSKLNGWRKPFMELIFMYDIIEFVFCSAGFTCILLAFTFGGNR 322

  Fly   277 --------LDFWMVSVVCVA----YYVAIFPFVALGQA-----------------FFVSNFHMTP 312
                    :..:::.:|.|.    |...:||...:.:|                 .|..|..:..
Yeast   323 YAWNSASIIILFIIGIVLVVLAGIYDFLVFPKFNIVKATPHYQPLMSWTNIKKPGIFTVNIALFL 387

  Fly   313 DEANTVNSIVYLI------------------------SAIASPLFGFVIDK--------VGRNVT 345
            ..|..::...|::                        :.:.:.|.|.:.||        |..::.
Yeast   388 TCAGYISQFTYIVQYFQLIYNDSAWRAAVHLVACIISTVVTAILCGAITDKTRQIKPIIVISSIF 452

  Fly   346 WVFCATISTLLAHFLLTFTHLDPYIGMSIM-GLSYSMLAASLWPLVSLIVPEYQLG--------- 400
            .|..|.|.|||.:......|    ||:.|: |:::..||.|     |::..:.||.
Yeast   453 GVVGAGILTLLNNNANNSAH----IGLLILPGVAFGGLAQS-----SMLASQIQLDKKSPTFRSD 508

  Fly   401 -----TAYGFCQSVQNLGLAV---------------------VTIAAGIIVD--------SSGGS 431
                 |...||   :|||.|:                     :.:..|..||        :..||
Yeast   509 FVSITTFNTFC---KNLGQALGGVISNTVFSAAAIKKLTKANIQLPDGTTVDNLVIYRQTNFDGS 570

  Fly   432 HFWL---------QVFFMSFLLVSLLATCAIWAYNRKHQGNL 464
            |..|         .||:|:....:|....|::|.|:|...:|
Yeast   571 HSKLGNIISESLTDVFYMALGFYALSLIFAVFASNKKVTASL 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12194	NP_001162873.1	MFS	61..454	CDD:119392	102/572 (18%)
		MFS_1	64..416	CDD:284993	86/492 (17%)
AZR1	NP_011740.3	MFS_Azr1_MDR_like	83..540	CDD:341045	86/502 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341820
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930