DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tank and ei24

DIOPT Version :9

Sequence 1:	NP_608864.1	Gene:	tank / 33684	FlyBaseID:	FBgn0031635	Length:	497	Species:	Drosophila melanogaster
Sequence 2:	NP_001017898.1	Gene:	ei24 / 550597	ZFINID:	ZDB-GENE-050417-457	Length:	340	Species:	Danio rerio

Alignment Length:	350	Identity:	145/350 - (41%)
Similarity:	200/350 - (57%)	Gaps:	54/350 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AAIKNITLGILYGLWDSIRGMTLVLHIDDEVNRQNAEQEHRQQLRRTDKDRYERARRSPSPVPSS 66
            |.::|:..||.    |||.|:..:..:|..:.::..||               |.|||     |.
Zfish     7 AFLRNVATGIK----DSILGIGTISKLDARIQQKREEQ---------------RRRRS-----SG 47

  Fly    67 AAAMIREEYAKQAEENADERTLEKILGKKPAAQDQHPQGEKKIAKKLFKCCMLNGGFTWLSIVLF 131
            |.||.|    .|:||.               .||..|    |:..::|:||..|||..|||:.||
Zfish    48 ALAMRR----AQSEER---------------KQDSEP----KLVSRIFQCCAWNGGVFWLSLFLF 89

  Fly   132 ENALLPTLKFCLTIFYG---AHSETLPVVWGWLHPILSLLFGMMWVLPIFMLSKIVSSLWFADIA 193
            ....:|.|:.......|   .|..    ||.||..||:.:|..:||||:|:|||||:::||.|||
Zfish    90 YRVFIPLLQSLTARIIGDPSLHGN----VWSWLEFILTSVFSALWVLPLFVLSKIVNAIWFQDIA 150

  Fly   194 NAAYRVRKGRPQLIPGISKLVADFLFSMVVQMLFLVQSMLVNLVPVKYVGSSLCFVHLCLLYSLY 258
            :.|:.|...:.|..|.:||::||.||::::|.|||:|..:|:|.|:..:|..:..:|:.||||||
Zfish   151 DLAFEVSGRKAQPFPSVSKIIADMLFNLLLQALFLIQGWIVSLFPIDAIGQLVSLLHMSLLYSLY 215

  Fly   259 SFEYKWFNMGWELHRRLTYIEKNWPYFFGFGIPLTVLTNLSSSVIVSSCIFSIFFPLFILSGNEA 323
            .|||:|||.|.|:|:||:.||:||||:||||:|:.:||.|.||.|:|.|:|||.|||||:|.|||
Zfish   216 CFEYRWFNHGIEMHQRLSNIERNWPYYFGFGLPMALLTALPSSYIISGCLFSILFPLFIISANEA 280

  Fly   324 KPIVDTTEVSLRLFSPVVFISNLCF 348
            |..|......|||||.||.|||..|
Zfish   281 KTPVKLYHFQLRLFSLVVLISNKLF 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tank	NP_608864.1	EI24	164..296	CDD:284638	66/131 (50%)
ei24	NP_001017898.1	EI24	120..256	CDD:284638	68/135 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582199
Domainoid	1	1.000	198	1.000	Domainoid score	I3048
eggNOG	1	0.900	-	-		E1_KOG3966
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3588
Inparanoid	1	1.050	257	1.000	Inparanoid score	I3140
OMA	1	1.010	-	-		QHG55407
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005680
OrthoInspector	1	1.000	-	-		oto40195
orthoMCL	1	0.900	-	-		OOG6_104073
Panther	1	1.100	-	-	LDO	PTHR21389
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4663
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.760