Protein Alignment tank and Ei24

DIOPT Version :10

• Sequence 1: NP_608864.1
• Gene: tank / 33684
• FlyBaseID: FBgn0031635
• Length: 497
• Species: Drosophila melanogaster
• Sequence 2: NP_031941.2
• Gene: Ei24 / 13663
• MGIID: 108090
• Length: 340
• Species: Mus musculus
• Alignment Length: 349
• Identity: 130/349 - (37%)
• Similarity: 198/349 - (56%)
• Gaps: 50/349 - (14%)

  Fly     3 AIKNITLGILYGLWDSIRGMTLVLHIDDEVNRQNAEQEHRQQLRRTDKDRYERARRSPSPVPSSA 67
            ::|.....:..|:.|||.|:..:..:|..:.::..||..|:                       |
Mouse     4 SVKTFLQDLGRGIKDSIWGICTISKLDARIQQKREEQRRRR-----------------------A 45

  Fly    68 AAMIREEYAKQAEENADERTLEKILGKKPAAQDQHPQGEKKIAKKLFKCCMLNGGFTWLSIVLFE 132
            ::::.:                    ::|.:.::..:.|.:|..::|:||..|||..|.|::||.
Mouse    46 SSLLAQ--------------------RRPQSVERKQESEPRIVSRIFQCCAWNGGVFWFSLLLFY 90

  Fly   133 NALLPTLKFCLTIFYG---AHSETLPVVWGWLHPILSLLFGMMWVLPIFMLSKIVSSLWFADIAN 194
            ...:|.|:.......|   .|.:    ||.||...|:.:|..:||||:|:|||:|:::||.|||:
Mouse    91 RVFIPVLQSVTARIIGDPSLHGD----VWSWLEFFLTSIFSALWVLPLFVLSKVVNAIWFQDIAD 151

  Fly   195 AAYRVRKGRPQLIPGISKLVADFLFSMVVQMLFLVQSMLVNLVPVKYVGSSLCFVHLCLLYSLYS 259
            .|:.|...:|...|.:||::||.||::::|.|||:|.|.|:|.|:..||..:..:|:.||||||.
Mouse   152 LAFEVSGRKPHPFPSVSKIIADMLFNLLLQALFLIQGMFVSLFPIHLVGQLVSLLHMSLLYSLYC 216

  Fly   260 FEYKWFNMGWELHRRLTYIEKNWPYFFGFGIPLTVLTNLSSSVIVSSCIFSIFFPLFILSGNEAK 324
            |||:|||.|.|:|:||:.||:||||:||||:||..||.:.||.|:|.|:|||.|||||:|.||||
Mouse   217 FEYRWFNKGIEMHQRLSNIERNWPYYFGFGLPLAFLTAMQSSYIISGCLFSILFPLFIISANEAK 281

  Fly   325 PIVDTTEVSLRLFSPVVFISNLCF 348
            .........|||||.|||:||..|
Mouse   282 TPGKAYLFQLRLFSLVVFLSNRLF 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tank	NP_608864.1	EI24	164..296	CDD:462129	67/131 (51%)
Ei24	NP_031941.2	Interaction with BH3 domain of BCL2	52..115		17/66 (26%)
		EI24	120..254	CDD:462129	68/133 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	319..340