Protein Alignment Ir25a and GLR3.4

DIOPT Version :10

• Sequence 1: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: NP_172012.2
• Gene: GLR3.4 / 839268
• AraportID: AT1G05200
• Length: 959
• Species: Arabidopsis thaliana
• Alignment Length: 1031
• Identity: 208/1031 - (20%)
• Similarity: 378/1031 - (36%)
• Gaps: 313/1031 - (30%)

  Fly    22 SSFSLEIAAQTTQNINVLFINEVDN------EPAAKAV-------EVVLTYLKKNIRYGLSVQLD 73
            ||.||....|...::||..:...|:      :||.||.       :.||..:|.||     :..|
plant    47 SSSSLRPLRQRPSSVNVGALFTYDSFIGRAAKPAVKAAMDDVNADQSVLKGIKLNI-----IFQD 106

  Fly    74 SIEANKSDAKVLLEAICNKYATSI--EKKQTPHLI--------LDTTKSGIASETVKSFTQALGL 128
            |..:........|:.:.||...:|  :.....|:|        :.....|....|:.|......|
plant   107 SNCSGFIGTMGALQLMENKVVAAIGPQSSGIAHMISYVANELHVPLLSFGATDPTLSSLQFPYFL 171

  Fly   129 PTISASYGQQGDLRQ------WRDL------DE-------------AKQK----YLLQVMPPADI 164
            .|....|.|...:..      ||.:      ||             ||::    |...:.|.||
plant   172 RTTQNDYFQMHAIADFLSYSGWRQVIAIFVDDECGRNGISVLGDVLAKKRSRISYKAAITPGAD- 235

  Fly   165 IPEAIRSIVIHMNITNAAILY-----DDSFVMDHKYKSLLQN------IQTRHVITAIAKDGKRE 218
             ..:||.:::.:|:..:.:..     |....:....|||...      |.|..:.||
plant   236 -SSSIRDLLVSVNLMESRVFVVHVNPDSGLNVFSVAKSLGMMASGYVWIATDWLPTA-------- 291

  Fly   219 REEQIEKLRNLDINNFFILGTLQSIR--MVLESVKPAYFERNFAWHAITQNEGEISSQRDNATIM 281
                ::.:.::|.:...:|..:.:.|  .:..|||..:..|   |..:..|:|
plant   292 ----MDSMEHVDSDTMDLLQGVVAFRHYTIESSVKRQFMAR---WKNLRPNDG------------ 337

  Fly   282 FMKPMAYTQYRDRLGLLRTTYNLNEEPQLSSAFYFDLALRSFLTIKEMLQSGAWPKDMEYLNCDD 346
                                :|       |.|.|   |..|...:...|       |:.:...::
plant   338 --------------------FN-------SYAMY---AYDSVWLVARAL-------DVFFRENNN 365

  Fly   347 FQGGNTPQRNLDLRDYFTKITEPTSYGTFDLVTQSTQPFN-GHSFMK---------------FEM 395
            ....|.|  ||          ..|:..|..|...|.  || |..|||               |:.
plant   366 ITFSNDP--NL----------HKTNGSTIQLSALSV--FNEGEKFMKIILGMNHTGVTGPIQFDS 416

  Fly   396 DIN-------VLQIRGGSSVNSKSIGKWI--SGLNSELIVKDE-------------EQMKNLTAD 438
            |.|       ||.:.|.:   .:::|.|.  |||:   :|..|             :::|.:
plant   417 DRNRVNPAYEVLNLEGTA---PRTVGYWSNHSGLS---VVHPETLYSRPPNTSTANQRLKGI--- 472

  Fly   439 TVYR----------IF-------------TVVQAPFIMRDETAPKGYKGYCIDLINEIAAIVHFD 480
             :|.          :|             .|....::.:|:. |.|.:|||||:..  |||....
plant   473 -IYPGEVTKPPRGWVFPNNGKPLRIGVPNRVSYTDYVSKDKN-PPGVRGYCIDVFE--AAIELLP 533

  Fly   481 YTIQEV----EDGKFGNMDENGQWNGIVKKLMDKQADIGLGSMSVMAEREIVIDFTVPYYD--LV 539
            |.:...    .|||     .|..::.:|.:::....|:.:|.::::..|...:|||.|:.:  ||
plant   534 YPVPRTYILYGDGK-----RNPSYDNLVNEVVADNFDVAVGDITIVTNRTRYVDFTQPFIESGLV 593

  Fly   540 GITIMMQRPSSPSSLFKFLTVLETNVWLCILAAYFFTSFLMWIFDRWSPYSYQNNREKYKDDEEK 604
            .:..:.:..|||.|..|..|:   .:|......:.|...::||.:      ::.|:| ::....:
plant   594 VVAPVKEAKSSPWSFLKPFTI---EMWAVTGGFFLFVGAMVWILE------HRFNQE-FRGPPRR 648

  Fly   605 REFNLKECLWFCMTSLTPQGGGEAPKNLSGRLVAATWWLFGFIIIASYTANLAAFLTVSRLDTPV 669
            :   |....||..:::..........:| ||.|...|.....||.:||||:|.:.||:.:|.:.:
plant   649 Q---LITIFWFSFSTMFFSHRENTVSSL-GRFVLIIWLFVVLIINSSYTASLTSILTIRQLTSRI 709

  Fly   670 ESLDDLAKQYKILYAPL---NGSSAMTYFERMSNIEQMFYEIWKDLSLNDSLTAVERSKLAVWDY 731
            |.:|.|....:    |:   :|:.|..|.....||..                    |::.
plant   710 EGIDSLVTSNE----PIGVQDGTFARNYLINELNILP--------------------SRIV---- 746

  Fly   732 PVSDKYTKMWQAMQEAKLPATLDEAVARVRNSTAATGFAFLGDATDIRYLQL----TNCDLQVVG 792
            |:.|:                 ::.::.::....|.|.|.:.|  ::.|:::    :||..:.||
plant   747 PLKDE-----------------EQYLSALQRGPNAGGVAAIVD--ELPYIEVLLTNSNCKFRTVG 792

  Fly   793 EEFSRKPYAIAVQQGSHLKDQFNNAILTLLNKRQLEKLKEKW--WKNDEALAKCDKPEDQSDGIS 855
            :||:|..:..|.|:.|.|....:.|||.|..:.:|||:..||  :|::.::...:..:.|   :|
plant   793 QEFTRTGWGFAFQRDSPLAVDMSTAILQLSEEGELEKIHRKWLNYKHECSMQISNSEDSQ---LS 854

  Fly   856 IQNIGGVFIVIFVGIGMACITLVFEYWWYRYRKNPRIIDVAEANAERSNAADHPGK 911
            :::..|:|::    .|:.|...:..::|..:.:..|::. ..|:.||:.....|.:
plant   855 LKSFWGLFLI----CGITCFMALTVFFWRVFWQYQRLLP-ESADEERAGEVSEPSR 905

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	37..418	CDD:380606	88/470 (19%)
		PBP2_iGluR_putative	438..836	CDD:270435	96/435 (22%)
GLR3.4	NP_172012.2	PBP1_GABAb_receptor_plant	62..450	CDD:380645	91/478 (19%)
		Lig_chan-Glu_bd	507..591	CDD:463166	24/91 (26%)
		Lig_chan	613..867	CDD:459656	67/321 (21%)