Protein Alignment Ir25a and GLR2.5

DIOPT Version :10

• Sequence 1: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: NP_001332219.1
• Gene: GLR2.5 / 830991
• AraportID: AT5G11210
• Length: 918
• Species: Arabidopsis thaliana
• Alignment Length: 1018
• Identity: 202/1018 - (19%)
• Similarity: 371/1018 - (36%)
• Gaps: 267/1018 - (26%)

  Fly    12 LWLLGFLSLL---SSFSLEIAAQTTQNINVLFINEVDNEPAAKAVEVVLTYLKKNIRYGLSVQLD 73
            ||||.||..|   ...|.:.|.|....| ||..|....:.:.:|:.:.|:.. .|...|...:
plant    14 LWLLIFLVFLVLSLGKSQKEALQVKVGI-VLGSNVTLADLSLRAINMSLSEF-YNTHNGFKTR-- 74

  Fly    74 SIEANKSDAKVLLEAICNKYATSIEKKQTPHLILDTTKSGIASETVKSFTQALG----LPTISAS 134
             |..|..|:|..:..........|:|::...:|      |..:.....|...||    :|.|  |
plant    75 -IVLNVRDSKQTVVGAAASALYLIKKREVVAII------GPGTSMQAPFLINLGNQSKVPII--S 130

  Fly   135 YGQQGDLRQWRDLDEAKQKYLLQVMPPADIIPEAIRSIVIHMNITNAAILY-DDSF-------VM 191
            :.....|     ||..:..|.::.........:||.:|:..........:| |:.|       ::
plant   131 FSATSPL-----LDSLRSPYFIRATHDDSSQVQAISAIIESFRWREVVPIYVDNEFGEGILPNLV 190

  Fly   192 DHKYKSLLQNIQTRHVITAIAKDGKREREEQIEKLRNLDINNFFI-----LGT-LQSIRMVLESV 250
            | .::.:...|:.|..|:....|.:.::|  :.||..:....|.:     ||: |.||...::.:
plant   191 D-AFQEINVRIRYRSAISLHYSDDQIKKE--LYKLMTMPTRVFIVHMLPDLGSRLFSIAKEIDML 252

  Fly   251 KPAYFERNFAWHAITQNEGEISSQRDNATIMFM-------------KPMAY--TQYRDRLGLLRT 300
            ...|     .| .:|....::.|....::::.|             |.:.:  .:::.|.|
plant   253 SKGY-----VW-IVTNGIADLMSIMGESSLVNMHGVLGVKTYFAKSKELLHLEARWQKRFG---- 307

  Fly   301 TYNLNEEPQLSSAFYFDLALRSFLTIKEMLQSGAWPKDMEYLNCDDFQGGNTPQRNLDLRDYFT- 364
                .||....:.:.:|.|....::::|          :.::|    ...||.:.:....|..|
plant   308 ----GEELNNFACWAYDAATALAMSVEE----------IRHVN----MSFNTTKEDTSRDDIGTD 354

  Fly   365 -----------KITEPTSYGTFDLVTQSTQPFNGHSFMKFEMDINVLQIRGGSSVNSKSIGKWIS 418
                       |:.:..|..:|..|....|..||      :::....:|........:::|.|.|
plant   355 LDELGVALSGPKLLDALSTVSFKGVAGRFQLKNG------KLEATTFKIINIEESGERTVGFWKS 413

  Fly   419 --GLNSELIVKDEEQMKNLTADTVYRIFTVVQAPFIMRDET--APKGYK---------------- 463
              ||           :|:|..|.|......:: |.|...:|  .|||::
plant   414 KVGL-----------VKSLRVDKVSHSSRRLR-PIIWPGDTIFVPKGWEFPTNAKKLRIAVPKKD 466

  Fly   464 --------------------GYCIDLINEIAA----IVHFDYTIQEVEDGKFGNMDENGQWNGIV 504
                                |:|||:.|.:.:    .|.::|...:..|||     ..|.::.:|
plant   467 GFNNFVEVTKDENTNVPTVTGFCIDVFNTVMSQMPYAVSYEYIPFDTPDGK-----PRGSYDEMV 526

  Fly   505 KKLMDKQADIGLGSMSVMAEREIVIDFTVPYYDLVGITIMMQRPSSPSSLFKFLTVLETNVWLCI 569
            ..:...:.|..:|..:::|.|...:||.:||.:...:.::..:.......:.||..|...:||..
plant   527 YNVFLGEFDGAVGDTTILANRSHYVDFALPYSETGIVFLVPVKDGKEKGEWVFLKPLTKELWLVT 591

  Fly   570 LAAYFFTSFLMWIFDRWSPYSYQNNREKYKDDEEKRE----FNLKECLWFCMTSL-----TPQGG 625
            .|::.:...::|||:             |:.|||.||    ..:....:|..::|     .|.
plant   592 AASFLYIGIMVWIFE-------------YQADEEFREQMIIDKISSVFYFSFSTLFFAHRRPS-- 641

  Fly   626 GEAPKNLSGRLVAATWWLFGFIIIASYTANLAAFLTVSRLDTPVESLDDLAKQ-YKILYAPLNGS 689
                ::...|::...|.....|:..||||.|.:.|||..|...|..:|||.|. ..|.|.  .||
plant   642 ----ESFFTRVLVVVWCFVLLILTQSYTATLTSMLTVQELRPTVRHMDDLRKSGVNIGYQ--TGS 700

  Fly   690 SAMTYFERMSNIEQMFYEIWKDLSLNDSLTAVERSKLAVWDYPVSDKYTKMWQAMQEAKLPATLD 754
            ..   |||   ::||.:               :.|:|..::.|         :.|:|..|.
plant   701 FT---FER---LKQMRF---------------DESRLKTYNSP---------EEMRELFLH---- 731

  Fly   755 EAVARVRNSTAATGFAFLGDATDIRYLQL---TNC-DLQVVGEEFSRKPYAIAVQQGSHLKDQFN 815
                  ::|......||    .::.|::|   ..| :..::...|....:..|...||.|....:
plant   732 ------KSSNGGIDAAF----DEVAYIKLFMAKYCSEYSIIEPTFKADGFGFAFPLGSPLVSDIS 786

  Fly   816 NAILTLLNKRQLEKLKEKWWKNDEALAKC------DKPEDQSDGISIQNIGGVFIVIFVGIGMAC 874
            ..||.:.....::.::.||:..::   .|      |.| .|.|..|.:   .:|:::|| :.:..
plant   787 RQILNITEGDAMKAIENKWFLGEK---HCLDSTTSDSP-IQLDHHSFE---ALFLIVFV-VSVIL 843

  Fly   875 ITLVFEYWWYRYRK---NPRIIDVAEANA------ERSNAADH 908
            :.|:.....|:.|:   :|.:.: .:|||      |..|..||
plant   844 LLLMLASRGYQERQHNASPNLPN-DQANAAQEEVNEEGNVGDH 885

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	37..418	CDD:380606	73/425 (17%)
		PBP2_iGluR_putative	438..836	CDD:270435	93/453 (21%)
GLR2.5	NP_001332219.1	PBP1_GABAb_receptor_plant	38..421	CDD:380645	78/448 (17%)
		GluR_Plant	456..806	CDD:270404	84/419 (20%)
		Lig_chan	584..838	CDD:459656	69/325 (21%)