Protein Alignment Ir25a and GLR5

DIOPT Version :10

• Sequence 1: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: NP_565744.1
• Gene: GLR5 / 817801
• AraportID: AT2G32400
• Length: 921
• Species: Arabidopsis thaliana
• Alignment Length: 958
• Identity: 190/958 - (19%)
• Similarity: 372/958 - (38%)
• Gaps: 217/958 - (22%)

  Fly    35 NINVLF-INEVDNEPAAKAVEVVLTYLKKNIRYGLSVQLDSIEANKSDAKVLLE-AICNKYATS- 96
            ||..:| .:.|....|..|:|..::          .|..|.....:::.::|:| :.||.:..|
plant    32 NIGAVFAFDSVIGRAAKVALEAAVS----------DVNNDKSFLKETELRLLMEDSACNVFRGSF 86

  Fly    97 -----IEKK----------QTPHLILDTTKSGIASETVKSFTQALGLPTISASY------GQQGD 140
                 :||:          ...|.|.|..| |:....| ||  |...||:||..      ....|
plant    87 GAFELLEKEVVAMIGPISSSVAHTISDIAK-GLHFPLV-SF--AATDPTLSALQFPFFLRTTPND 147

  Fly   141 LRQWRDLDEAKQKY----LLQVMPPADIIPEAIRSIVIHMNITNAAILY--------DDSFVMDH 193
            ..|...|.:....|    ::.|....::....:.::...:....:.|.|        |:.|:.:.
plant   148 AHQMSALVDLINFYGWKEVISVYSDDELGRNGVSALDDELYKKRSRISYKVPLSVHSDEKFLTNA 212

  Fly   194 KYKSLLQNIQTRHVITAIAKDGKREREEQIEKLR--------------NLDINNFFILGTLQSIR 244
            ..||  ::|..|..|.....|......:..:||:              ::.:::....|||:.:.
plant   213 LNKS--KSIGPRVYILHFGPDPLLRIFDIAQKLQMMTHEYVWLATDWLSVTLDSLSDKGTLKRLE 275

  Fly   245 MVL-------ESVKPAYFERN---------FAWHA------ITQNEGEISSQRDNATIMFMKPMA 287
            .|:       ||||..:|...         :|.||      |.....|:.::..|.|..:.:.:.
plant   276 GVVGLRQHIPESVKMEHFTHKLQSNRSMNAYALHAYDTVWMIAHGIEELLNEGINITFSYSEKLL 340

  Fly   288 YTQYRDRLGLLRTTYNLNEEPQLSSAFYFDLALRSFLTIKEMLQSGAWPKDMEYLNCDDFQGGNT 352
            :.: ..:|.|.:..:..:.|..|..     |...:|..|...:|.|:   ....:.| |::..|.
plant   341 HAR-GTKLHLEKIKFFNSGELLLEK-----LLKVNFTGIAGQVQFGS---GRNVIGC-DYEIINV 395

  Fly   353 PQRNLDLRDYFTKITEPTSYGTFDLVTQSTQPFNGHSFMKFEMDINVLQIRGGSSVNSKSIG--K 415
            .:.::....:::|      .|.|.:|...|:    ||..|            .|.|:.:.:|  .
plant   396 NKTDVHTVGFWSK------NGGFSVVAPKTR----HSQKK------------TSFVSDEKLGDIT 438

  Fly   416 WISGLNSE----LIVKDEEQMKNLTADTVYRIFTVVQAPFIMRDETAPKGYKGYCIDLINEIAAI 476
            |..|...:    :|....:.:|.:    |.|..:.|:  |:..::.:....:|:|||:.  |.|:
plant   439 WPGGGREKPRGWVIADSADPLKIV----VPRRVSFVE--FVTEEKNSSHRIQGFCIDVF--IEAL 495

  Fly   477 VHFDYTIQEVEDGKFGNMDENGQWNGIVKKLMDKQADIGLGSMSVMAEREIVIDFTVPYYDLVGI 541
            ....|::..:.: .|||...:..:|.:::.:.|...|..:|.::::..|..::||:.||.. .|:
plant   496 KFVPYSVPYIFE-PFGNGHSSPNYNHLIQMVTDGVYDAAVGDIAIVPSRSKLVDFSQPYAS-TGL 558

  Fly   542 TIMMQRPSSPSSLFKFLTVLETNVWLCILAAYFFTSFLMWIFDRWSPYSYQNNREKYKDDEEKRE 606
            .:::. .:..::.:.||....:.:|..:|.::...:.::||.:       ....|.::....::
plant   559 VVVIP-ANDDNATWIFLRPFTSRLWCVVLVSFLVIAVVIWILE-------HRINEDFRGPPRRQ- 614

  Fly   607 FNLKECLWFCMTSLTPQGGGEAPKNLSGRLVAATWWLFGFIIIASYTANLAAFLTVSRLDTPVES 671
              |...|.|..::|..:...:...||: |||...|.....::.|||||||.:.|||.:|.:.:..
plant   615 --LSTMLLFSFSTLFKRNQEDTISNLA-RLVMIVWLFLLMVLTASYTANLTSILTVQQLPSAITG 676

  Fly   672 LDDL-AKQYKILYAPLNGSSAMTYFERMSNIEQMFYEIWKDLSLNDSLTAVERSKLAVWDYPVSD 735
            :|.| |.:..|      |..|.|:     .:|.:.|.:           .:.||:|...|  .::
plant   677 IDSLRASEVPI------GYQAGTF-----TLEYLTYSL-----------GMARSRLVPLD--STE 717

  Fly   736 KYTKMWQAMQEAKLPATLDEAVARVRNSTAATGFAFLGDATDIRYLQL---TNCDLQVVGEEFSR 797
            :|.|      ..||..|....||.:              ..::.|::|   .....::|||.|..
plant   718 EYEK------ALKLGPTNWGGVAAI--------------VDELPYIELFLAERTGFKIVGEPFMH 762

  Fly   798 KPYAIAVQQGSHLKDQFNNAILTLLNKRQLEKLKEKWWKNDEALAKCD-KPEDQSDGISIQNIGG 861
            :.:..|.::.|.|....:.|||.|...|:|:::::||........|.: .||...  :.:::..|
plant   763 RGWGFAFKRDSPLAIDMSTAILKLSETRKLQEIRKKWLCKTNCAGKSNWNPEPNQ--LHLKSFKG 825

  Fly   862 VFIVIFVGIGMACITLVFEYW----------WYRYRKNPRIIDVAEAN 899
            :::|        ||.:....:          :.|||:..|...:..|:
plant   826 LYLV--------CIAITVSAFLVFVLRMIRQFVRYRRMERTSSMPRAS 865

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	37..418	CDD:380606	84/454 (19%)
		PBP2_iGluR_putative	438..836	CDD:270435	89/401 (22%)
GLR5	NP_565744.1	PBP1_GABAb_receptor_plant	32..416	CDD:380645	77/415 (19%)
		GluR_Plant	458..800	CDD:270404	89/407 (22%)
		Lig_chan	578..832	CDD:459656	69/318 (22%)