Protein Alignment Ir25a and GLR2.7

DIOPT Version :10

• Sequence 1: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: NP_180476.3
• Gene: GLR2.7 / 817460
• AraportID: AT2G29120
• Length: 952
• Species: Arabidopsis thaliana
• Alignment Length: 1038
• Identity: 193/1038 - (18%)
• Similarity: 371/1038 - (35%)
• Gaps: 300/1038 - (28%)

  Fly     1 MILMNPKTSKILWLLGFLSLLSSFSLE---IAAQTTQNIN---VLFINEVDNEPAAKAVEVVLT- 58
            |.:|||:.:...::..|:..:..|.|.   :....|..|.   ||.::...::....::.:.|:
plant     1 MKVMNPRKTNNTFMYYFVLFVCGFVLMEGCLGQNQTTEIKVGVVLDLHTSFSKLCLTSINISLSD 65

  Fly    59 YLKKNIRY--GLSVQL-DSIEANKSDAKVLLEAICNKYATSI----------------EKKQTPH 104
            :.|.:..|  .|::.: ||:|.....:...|:.|.|:..::|                :|.|.|.
plant    66 FYKYHSDYTTRLAIHIRDSMEDVVQASSAALDLIKNEQVSAIIGPRTSMQAEFMIRLADKSQVPT 130

  Fly   105 LILDTTKSGIAS--------ETVKSFTQALGLPTISASYGQQGDLRQWRD-----LDEAKQKYLL 156
            :....|...:.|        .|:...:|...:..|..|:|       ||:     :|....:.:|
plant   131 ITFSATCPLLTSINSPYFVRATLDDSSQVKAIAAIVKSFG-------WRNVVAIYVDNEFGEGIL 188

  Fly   157 QVMPPADIIPEAIRSIVIHMNITNAAILYDDSFVMDHKYKSLLQNIQTRHVITA----------- 210
            .::  .|.:.:....:|....|...|   :|..::...||  |..:|||..:..
plant   189 PLL--TDALQDVQAFVVNRCLIPQEA---NDDQILKELYK--LMTMQTRVFVVHMPPTLGFRFFQ 246

  Fly   211 --------------IAKDG------KREREEQIEKLRNLDINNFFILGT---------LQSIRMV 246
                          :..||      ..||...:|.::.       :||.         |::.|:.
plant   247 KAREIGMMEEGYVWLLTDGVMNLLKSNERGSSLENMQG-------VLGVRSHIPKSKKLKNFRLR 304

  Fly   247 LESVKPAY---FERNF----AWHAITQNEGEISSQRDN-ATIMFMKPMAYTQYRDRLGLLRTT-Y 302
            .|.:.|..   .|.|.    |:.:||..  .::.::.| .::.:..|:|....:..||.|..: |
plant   305 WEKMFPKKGNDEEMNIFALRAYDSITAL--AMAVEKTNIKSLRYDHPIASGNNKTNLGTLGVSRY 367

  Fly   303 NLNEEPQLSSAFYFDLALRSFLTIKEMLQSGAWPKDMEYLNCDDFQGGNTPQRNLDLRDYFTKIT 367
            ..:....||:..:..|| ..|..|...|:|..:    :.:|.
plant   368 GPSLLKALSNVRFNGLA-GEFELINGQLESSVF----DVINI----------------------- 404

  Fly   368 EPTSYGTFDLVTQSTQPFNGHSFMKFEMDINVLQIRGGSSV---NSKSIGK-WISGLNSELIVKD 428
                .|:.:.:....:|.||....|.:...:||..|.|..:   .||.:.| |....|.:::
plant   405 ----IGSEERIIGLWRPSNGIVNAKSKNTTSVLGERLGPVIWPGKSKDVPKGWQIPTNGKML--- 462

  Fly   429 EEQMKNLTADTVYRIFTVVQAPFI---------MRDETAPKGYKGYCIDLINEIAAIVHFDYTIQ 484
                         |:...|:..|:         :.:...|   .||||::...:...:.:....:
plant   463 -------------RVGIPVKKGFLEFVDAKIDPISNAMTP---TGYCIEIFEAVLKKLPYSVIPK 511

  Fly   485 EVEDGKFGNMDENGQWNGIVKKLMDKQADIGLGSMSVMAEREIVIDFTVPYYDLVGITIMMQRPS 549
            .:   .|.:.|||  ::.:|.::.....|..:|.::::|.|.:.:|||:||.: .|:::|:....
plant   512 YI---AFLSPDEN--YDEMVYQVYTGAYDAVVGDVTIVANRSLYVDFTLPYTE-SGVSMMVPLKD 570

  Fly   550 SPSSLFKFLTVLETNVWLCILAAYFFTSFLMWIFD-------RWSPYSYQNNREKYKDDEEKREF 607
            :.:: :.||.....::|:.....:.|..|::||.:       |..|:                 .
plant   571 NKNT-WVFLRPWSLDLWVTTACFFVFIGFIVWILEHRVNTDFRGPPH-----------------H 617

  Fly   608 NLKECLWFCMTSLTPQGGGEAPKNLSGRLVAATWWLFGFIIIASYTANLAAFLTVSRLDTPVESL 672
            .:....||..:::......:...||: |.|...|.....::|.||||||.:|.||..|...|.:.
plant   618 QIGTSFWFAFSTMNFAHREKVVSNLA-RFVVLVWCFVVLVLIQSYTANLTSFFTVKLLQPTVTNW 681

  Fly   673 DDLAKQYKILYAPLNGSSAMTYFERMSNIEQMFYEIWKDLSLNDSL-----TAVERSKLAVWDYP 732
            .||.|..|.:     |....|:..          |:.|....::|.     :|||..:|
plant   682 KDLIKFNKNI-----GYQRGTFVR----------ELLKSQGFDESQLKPFGSAVECDEL------ 725

  Fly   733 VSDKYTKMWQAMQEAKLPATLDEAVARVR-----NSTAATGFAFLGDATDIRYLQLTNCDLQVVG 792
                       .....:.|:.|| ||.::     ||:..|                      :|.
plant   726 -----------FSNGTITASFDE-VAYIKVILSQNSSKYT----------------------MVE 756

  Fly   793 EEFSRKPYAIAVQQGSHLKDQFNNAILTLLNKRQLEKLKEKWWKNDEALAKCDKPED-------- 849
            ..|....:.....:.|.|.|..:.|||.:....:::.::.||:|         ||.:
plant   757 PSFKTAGFGFVFPKKSPLTDDVSRAILNVTQGEEMQHIENKWFK---------KPNNCPDLNTSL 812

  Fly   850 QSDGISIQNIGGVFIVIFVGIGMACITLVFEYWWYRYRKNPRIIDVAEANAERSNAADHPGKL 912
            .|:.:|:.:..|:|::..:...:|.:..|..   :.|.....:.|.:| |:.|       |||
plant   813 SSNHLSLSSFWGLFLIAGIASFLALLIFVAN---FLYEHKHTLFDDSE-NSFR-------GKL 864

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	37..418	CDD:380606	83/469 (18%)
		PBP2_iGluR_putative	438..836	CDD:270435	83/423 (20%)
GLR2.7	NP_180476.3	PBP1_GABAb_receptor_plant	40..423	CDD:380645	74/437 (17%)
		GluR_Plant	460..799	CDD:270404	82/437 (19%)
		Lig_chan	582..832	CDD:459656	64/331 (19%)