Protein Alignment Ir25a and GLR2.2

DIOPT Version :10

• Sequence 1: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: NP_180048.1
• Gene: GLR2.2 / 817008
• AraportID: AT2G24720
• Length: 920
• Species: Arabidopsis thaliana
• Alignment Length: 1008
• Identity: 198/1008 - (19%)
• Similarity: 352/1008 - (34%)
• Gaps: 285/1008 - (28%)

  Fly     7 KTSKILWLLGFLSLLSSFSLEIA-----AQTTQNINVLFINEVDNEPAAKAVEVVLTYLKKNIR- 65
            |.||:.:  .||.|...|.||.:     .:|..||.|:      ::......:|.:..:..::.
plant     2 KNSKLFF--RFLFLFFFFCLESSRGQDNGKTQVNIGVV------SDVGTSYPDVAMLCINMSLAD 58

  Fly    66 -YGLSVQLDS-IEANKSDAK--------VLLEAICNKYATSI----------------EKKQTPH 104
             |....|..: :..|..|:|        ..::.|.||...:|                :|.:.|.
plant    59 FYSSRPQFQTRLVVNVGDSKNDVVGAATAAIDLIKNKQVKAILGPWTSMQAHFLIEIGQKSRVPV 123

  Fly   105 LILDTTKSGIAS--------ETVKSFTQALGLPTISASYGQQGDLRQWRDLDEAKQKYLLQVMPP 161
            :....|...:.|        .|.:..:|...:..|...:|       ||
plant   124 VSYSATSPSLTSLRSPYFFRATYEDSSQVHAIKAIIKLFG-------WR---------------- 165

  Fly   162 ADIIPEAIRSIVIHMNITNAAILYDDSF---VMDHKYKSLLQNIQTRHVITAIAKDGKREREEQI 223
             :::|                :..|::|   :|.....| ||:|..|....::......:::..:
plant   166 -EVVP----------------VYIDNTFGEGIMPRLTDS-LQDINVRIPYRSVIPLNATDQDISV 212

  Fly   224 EKLRNLDI-NNFFILGTLQSIRMV-------LESVKPAYFERNFAWHAITQNEGEISSQRD-NAT 279
            |.|:.::: ...||:....|:...       |..:||.|     .|  |..| |.:...|. |.|
plant   213 ELLKMMNMPTRVFIVHMSSSLASTVFIKAKELGLMKPGY-----VW--ILTN-GVMDGLRSINET 269

  Fly   280 -------IMFMKPMAYTQYRDRLGLLRTTYNLNEEPQLSSAFY----FDLALRSFLTIKEMLQSG 333
                   ::.:|  .|......|...|:.:. ...||:....|    :|......:.|::
plant   270 GIEAMEGVLGIK--TYIPKSKDLETFRSRWK-RRFPQMELNVYGLWAYDATTALAMAIED----- 326

  Fly   334 AWPKDMEYLNCDDFQGGNTPQRN-LDLRDYFTKITEPTSYGTFDLVTQSTQPFNG----HSFMKF 393
            |...:|.:.|.|  .|.|..:.: |.|..:..|:          |.|.||..|.|    ..|:..
plant   327 AGINNMTFSNVD--TGKNVSELDGLGLSQFGPKL----------LQTVSTVQFKGLAGDFHFVSG 379

  Fly   394 EMDINVLQIRGGSSVNSKSIGKWISGLNSELIVKDEEQMKNLTA-----DTVYRIFTVVQAPFIM 453
            ::..:|.:|........:|||.|..|  :.|:.|.:::.:::..     |.:..|....:|
plant   380 QLQPSVFEIVNMIGTGERSIGFWTEG--NGLVKKLDQEPRSIGTLSTWPDHLKHIIWPGEA---- 438

  Fly   454 RDETAPKGY------------------------------------KGYCIDLINEIAAIVHFDYT 482
              .:.|||:                                    ||:|||....:...:.:|.:
plant   439 --VSVPKGWEIPTNGKKLRIGVPKRIGFTDLVKVTRDPITNSTVVKGFCIDFFEAVIQAMPYDVS 501

  Fly   483 IQEVEDGKFGNMDENGQWNGIVKKLMDKQADIGLGSMSVMAEREIVIDFTVPYYDL-VGITIMMQ 546
            .:.....| .|.:..|..|.:|.::...|.|..:|..:::|.|...:|||:|:... ||:.:.:
plant   502 YEFFPFEK-PNGEPAGNHNDLVHQVYLGQFDAVVGDTTILANRSSFVDFTLPFMKSGVGLIVPL- 564

  Fly   547 RPSSPSSLFKFLTVLETNVWLCILAAYFFTSFLMWIF------DRWSPYSYQNNREKYKDDEEKR 605
            :.......|.||..|...:||..|..:|.....:|..      |...|.:||
plant   565 KDEVKRDKFSFLKPLSIELWLTTLVFFFLVGISVWTLEHRVNSDFRGPANYQ------------- 616

  Fly   606 EFNLKECLWFCMTSL--TPQGGGEAPKNLSGRLVAATWWLFGFIIIASYTANLAAFLTVSRLDTP 668
               .....||..:::  .|:   |...:...|.:..||:....::..||||:||:.||..:|:..
plant   617 ---ASTIFWFAFSTMVFAPR---ERVLSFGARSLVVTWYFVLLVLTQSYTASLASLLTSQQLNPT 675

  Fly   669 VESLDDLAKQYKILYAPLNGSSAMTYFERMSNIEQMFYEIWKDLSLNDSLTAVERSKLAVWDYPV 733
            :.|:..|          |:....:.| :|.|.|      :.|   ||:  |...:|.|..:|
plant   676 ITSMSSL----------LHRGETVGY-QRTSFI------LGK---LNE--TGFPQSSLVPFD--- 715

  Fly   734 SDKYTKMWQAMQEAKLPATLDEAVAR-VRNSTAATGFAFLGDATDIRYLQL---TNCD-LQVVGE 793
                     ..:|.      ||.:.: .:|...|.  ||||..    |::|   ..|: .::|.|
plant   716 ---------TAEEC------DELLKKGPKNGGVAA--AFLGTP----YVRLFLGQYCNTYKMVEE 759

  Fly   794 EFSRKPYAIAVQQGSHLKDQFNNAILTLLNKRQLEKLKEKWWKNDEALAKCDKPEDQSDG----- 853
            .|:...:......||.|....:.|||.:....:..:|:..|:|..|  ..|..|....|.
plant   760 PFNVDGFGFVFPIGSPLVADVSRAILKVAESPKAVELEHAWFKKKE--QSCPDPVTNPDSNPTVT 822

  Fly   854 ---ISIQNIGGVFIVIFVGIGMACITLVFEYWW 883
               :.:.:...:|:|:||...:|.....|.:.|
plant   823 AIQLGVGSFWFLFLVVFVVCVLALGKFTFCFLW 855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	37..418	CDD:380606	77/443 (17%)
		PBP2_iGluR_putative	438..836	CDD:270435	94/447 (21%)
GLR2.2	NP_180048.1	PBP1_GABAb_receptor_plant	33..412	CDD:380645	81/455 (18%)
		GluR_Plant	452..801	CDD:270404	87/415 (21%)