Protein Alignment Ir25a and grik5l

DIOPT Version :10

• Sequence 1: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: NP_001072565.1
• Gene: grik5l / 780020
• XenbaseID: XB-GENE-5860197
• Length: 479
• Species: Xenopus tropicalis
• Alignment Length: 541
• Identity: 147/541 - (27%)
• Similarity: 252/541 - (46%)
• Gaps: 100/541 - (18%)

  Fly   407 SVNSKSIGKWISGLNSELIVKDEEQ-----MKNLTADTVYRIFTVVQAPFIMRDETAPKGYKGYC 466
            :|...|:|...:|.:...|.|::|:     :|:||      :.|:::.||.|:.|:   |.:|:|
 Frog    10 AVTLLSVGCTDAGESKGSIHKEKERSKRQALKHLT------VTTIMEQPFSMKTES---GMEGFC 65

  Fly   467 IDLINEIAAIVHFDYTIQEVEDGKFGNMDENGQWNGIVKKLMDKQADIGLGSMSVMAEREIVIDF 531
            |||::|:|..:.|:|||:||:||::|..|::|.|||:|.:::.|:||:.:..:::...||..:.|
 Frog    66 IDLLSELAQSLGFNYTIKEVKDGRYGAKDQDGNWNGMVGEVLRKEADLAVAPLTITGARERELAF 130

  Fly   532 TVPYYDLVGITIMMQRP--SSPSSLFKFLTVLETNVWLCILAAYFFTSFLMWIFDRWSPYSY--- 591
            |.|:.. .||:|::::.  |..|.||.|||......|:.||.||..||..:::..|.||..:
 Frog   131 TKPFMQ-TGISILLRKDDVSENSYLFGFLTPFSKETWIGILVAYVVTSLCLFLVGRLSPCEWTEL 194

  Fly   592 ---QNNREKYKDDEEKREFNLKECLWFCMTSLTPQGGGEAPKNLSGRLVAATWWLFGFIIIASYT 653
               |||            ||....|||.:.:.|.||....||::|.|::|..||:|..:::|:|.
 Frog   195 STEQNN------------FNFLNSLWFGVGAFTLQGAEPHPKSVSARIIAVIWWIFSIVLVAAYI 247

  Fly   654 ANLAAFLTVSRLDTP-VESLDDLAKQYKILYAPLNGSSAMTYFERMSNIEQMFYEIWKDLSLNDS 717
            |:.||||....:.|. :::.:||..|..:.:..:|.||...:|:...|
 Frog   248 ASFAAFLNSDSMQTTNIQTFEDLVNQRTLEFGTINSSSTFQFFKNSKN----------------- 295

  Fly   718 LTAVERSKLAVWDYPVSDKYTKMWQAMQEAK---LPATLDEAVARVRNSTAATGFAFLGDATDIR 779
                             ..|..:::.|.:.|   |..:..|.|.||:.|    .:||||::....
 Frog   296 -----------------PTYRMIYEYMDKRKDELLVKSFAEGVRRVKES----NYAFLGESVMQD 339

  Fly   780 YLQLTNCDLQVVGEEFSRKPYAIAVQQGSHLKDQFNNAILTLLNKRQLEKLKEKWWKNDEALAKC 844
            .:...:|||....:..:.:.|.||....|.|....:.|||.......:|.|::|||.|     .|
 Frog   340 IMVAKHCDLVRAPQIIAGRGYGIAASLDSPLIKPLSVAILEQTESGNIEYLRKKWWDN-----TC 399

  Fly   845 DKPEDQS-DGISIQNIGGVFIVIFVGIGMACITLVFEYWWYRYRKNPRIIDVAEANAERSNAADH 908
            :...... :.:....:||:|:::.:|:.:..|..:.|.             |.:|.    |.||.
 Frog   400 NMKRSAGWNPVQPHTLGGIFLILGIGLALGVIAALVEL-------------VLKAR----NNADQ 447

  Fly   909 PGKLVDGVILGHSGEKFEKSK 929
            ..|..........||:...:|
 Frog   448 QKKSCCSAFSEEMGERLGTNK 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	37..418	CDD:380606	3/10 (30%)
		PBP2_iGluR_putative	438..836	CDD:270435	119/409 (29%)
grik5l	NP_001072565.1	PBP2_iGluR_non_NMDA_like	41..396	CDD:270403	122/414 (29%)