Protein Alignment Ir25a and grin3ba

DIOPT Version :9

• Sequence 1: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: XP_021323058.1
• Gene: grin3ba / 566411
• ZFINID: ZDB-GENE-070912-354
• Length: 1118
• Species: Danio rerio
• Alignment Length: 1007
• Identity: 193/1007 - (19%)
• Similarity: 377/1007 - (37%)
• Gaps: 278/1007 - (27%)

  Fly    52 AVEVVLTYLKKN----IRYGLSVQLDSIEANKSDAKVLLEAICNKYATSIEKKQTPHLILDTTKS 112
            |:...|.:|:::    :.|.||:::.|.|....|.:.:...:|.                |....
Zfish    61 ALNRALVHLRQSGNNFLPYNLSLEVLSREPLNGDPESMFRCVCQ----------------DIVVQ 109

  Fly   113 GIASETVKSFTQA-------------LGLPTISASYGQQGDLRQWRDLDEAKQKYLLQV---MPP 161
            |:::  |.:|.|:             |.:|.||.       :.|...| :.:.::.||:   |||
Zfish   110 GVSA--VLAFPQSHEELIQVEFMSSFLEIPFISI-------IEQGEPL-KTQNRFHLQMMTRMPP 164

  Fly   162 ADIIPEAIRSIVIHMNIT-----------NAAILYD----DSFVMDHKYKSLLQNIQTRHVITAI 211
            :. :.:.:.::::.....           |..:|.:    ....:|..:..|.:.:....:...|
Zfish   165 SG-LSDLLLAVLLRGGWQGGAATVCPGGGNTGMLEELQQRGHLGLDGAHWHLWETLNLSRLEENI 228

  Fly   212 AKDGKREREEQ-IEKLRNLDINNFFILGT--------LQSIRMVLESVKPAYFERNF-----AWH 262
            ::|...|...| :.:..:...::..:.|:        |.....:..::.|.::...:     :.|
Zfish   229 SEDKVMELLSQLLSRTPSAPASSVVLFGSDPECTATVLHCAHQLSGTLPPMHWIMGYPLSLDSLH 293

  Fly   263 AI-----TQNEGEISSQ------RDNATIMFMKPMAYTQYRDRLGLLRTTYNLNEEPQLSSAFYF 316
            :|     ....||::.:      ||...::.....|.|..|..|.|::...|..::|..
Zfish   294 SIGSPLGLMAYGEVNRKPLNFYIRDTLQLIGRAVYAATMVRPDLALIQNMVNCFDKPNK------ 352

  Fly   317 DLALRSFLTIKEMLQSGAWPKDMEYLNCDDFQGGNTPQRNLDLRDYFTKITEPTSYGTFDLVTQS 381
                      .|:..||.:.  ..:|:...|.|...|.|   :...|:::.....:..:.|   .
Zfish   353 ----------HELPSSGQYL--ARFLSNTSFTGLTGPVR---VERSFSRVLTSQRFHIWSL---Q 399

  Fly   382 TQPFNGHSFM--------KFEMD-------INVLQIRGGSSVNSKSIGKWISGLNSELIVKDEEQ 431
            ..|....|::        :.|::       :...|...|..:  :..|:|.:||.
Zfish   400 RDPLGQPSWVTVASWQSGRLELEEQGLWPGVTQHQREDGPGI--RLGGRWQAGLP---------- 452

  Fly   432 MKNLTADTVYRIFTVVQAPFIMRDETAPKGY---------------------------------- 462
                .|.:..|:.|:|:.||:...|...:|.
Zfish   453 ----VAGSRLRVVTLVEHPFVFTREVDEEGQCPAGQLCLDPQTNNSEVLNQLFRELEQTNSSSLP 513

  Fly   463 -------KGYCIDLINEIAAIVHFDYTIQEVEDGKFGNMDENGQWNGIVKKLMDKQADIGLGSMS 520
                   .||||||:.::|..:||::.:..|.|||:|.. :.|:|:|:|..|:...||:.:.|.|
Zfish   514 TDMRKCCYGYCIDLLEKLAEDMHFEFDLYIVGDGKYGAW-KGGRWSGLVGDLLSGVADMAVTSFS 577

  Fly   521 VMAEREIVIDFTVPYYDL-VGITIMMQRPSSPSSLFKFLTVLETNVWLCILAAYFFTSFLMWIFD 584
            :.:.|..|||||.|::.. :||.:..:..::|  :..|:..|..::|:.|..|...|:..:.:::
Zfish   578 INSARSRVIDFTSPFFSTSLGILVRSKDTAAP--IGAFMWPLHWSMWVGIFVALHITALFITLYE 640

  Fly   585 RWSPYS---YQNNREKYKDDEEKREFNLKECLWFCMTSLTPQG-GGEAPKNLSGRLVAATWWLFG 645
            ..||:.   :..||        .|.|:....|..|...|..:. ..:.||..:||.:...|.:|.
Zfish   641 WNSPFGMTPHGRNR--------IRVFSYSSALNLCYAILFGRTVASKTPKCWTGRFLMNLWAIFC 697

  Fly   646 FIIIASYTANLAAFLTVSRLDTPVESLDDLAKQYKIL---YAPLNGSSAMTYFERMSNIEQMFYE 707
            .::::||||||||.:...:....|..:.|:...:..|   :..:..|||..|
Zfish   698 LLVLSSYTANLAAVMVGEKTFEEVSGIHDVKLHHPSLGFRFGTVRESSAEDY------------- 749

  Fly   708 IWKDLSLNDSLTAVERSKLAVWDYPVSDKYTKMWQAMQEAKLPATLDEAVARVRNSTAATG---- 768
                                     |...:.:|.:.|:....|.|.|..      ||..|.
Zfish   750 -------------------------VKKSFPEMHEYMRRFNKPTTPDGV------STLKTDPPQL 783

  Fly   769 FAFLGDATDIRY-LQL-TNCDLQVVGEEFSRKPYAIAVQQGSHLKDQFNNAILTLLNKRQLEKLK 831
            .||:.|...:.| :.: .:|.|..||:.|:.:.|.|.:.|.|.|....:..:....:...::.|.
Zfish   784 DAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPQNSPLTRNVSEYVSRYKSDGYMDMLH 848

  Fly   832 EKWWKNDEALAKCDK---PEDQSDGISIQNIGGVFIVIFVGIGMACITLV--------------- 878
            :||:|    :..|.|   ...::..:.||:..|:|:::.||:..|.:||:
Zfish   849 DKWYK----VVPCGKRVFAVTETLQMGIQHFSGLFVLLCVGVAGALLTLLGEHAFFRFILPHLRH 909

  Fly   879 ---FEYWWYRYRKNPRIIDVAEANAERSNAAD 907
               |:||.:..:|..|.|::. .:.||.:.|:
Zfish   910 QQRFKYWLHTSQKIHRAINMG-CDDERKSEAE 940

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	40..426	CDD:107378	69/448 (15%)
		PBP2_iGluR_putative	438..836	CDD:270435	102/452 (23%)
		Lig_chan	565..870	CDD:278489	68/320 (21%)
grin3ba	XP_021323058.1	Periplasmic_Binding_Protein_Type_1	26..428	CDD:324556	63/417 (15%)
		PBP2_iGluR_NMDA_Nr3	457..852	CDD:270438	101/449 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591833
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740