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Protein Alignment Ir25a and Gria3

DIOPT Version :9

Sequence 1:	NP_001260049.1	Gene:	Ir25a / 33683	FlyBaseID:	FBgn0031634	Length:	947	Species:	Drosophila melanogaster
Sequence 2:	NP_001268858.2	Gene:	Gria3 / 53623	MGIID:	95810	Length:	888	Species:	Mus musculus

Alignment Length:	973	Identity:	258/973 - (26%)
Similarity:	426/973 - (43%)	Gaps:	207/973 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 TQNINVLFINEVDNEPAAKAVEVVLTYLKKNIR---YGLSVQLDSIEANKSDAKVLLEAICNKYA 94
            |.:|..||:.....|.:|....|.|....:|..   :.|:..:|.::::.|.:  :..|.|::::
Mouse    27 TISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFS--VTNAFCSQFS 89

  Fly    95 TSIEKKQTPHLILDTTKSGIASETVKSFTQALGLPTISASYGQQGDLRQWRDLDEAKQKYLLQVM 159
            ..:      :.|...... ::..|:.||..||....::.|:....|:           ::::|:.
Mouse    90 RGV------YAIFGFYDQ-MSMNTLTSFCGALHTSFVTPSFPTDADV-----------QFVIQMR 136

  Fly   160 PPADIIPEAIRSIVIHMNITNAAILYDDSFVMDHKYKSLLQNI-----QTRHVITA--------- 210
            |   .:..||.|::.:........|||     ..:..|:||.|     |....:||
Mouse   137 P---ALKGAILSLLGYYKWEKFVYLYD-----TERGFSILQAIMEAAVQNNWQVTARSVGNIKDI 193

  Fly   211 -----IAKDGKREREE------QIEKLRNLDINNFFILG-----------TLQSIRMVLESVKPA 253
                 |.::..|.:|:      ::|:: |..:....|||           .|....:|||.|  .
Mouse   194 QEFRRIIEEMDRRQEKRYLIDCEVERI-NTILEQVVILGKHSRGYHYMLANLGFTDIVLERV--M 255

  Fly   254 YFERNFAWHAITQNEGEISSQ---------------RDNATIMFMKPMAYTQYRDRLGLLRTTYN 303
            :...|.....|..||..:..|               ..||      |:.||.......:|
Mouse   256 HGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNA------PLKYTSALTHDAIL----- 309

  Fly   304 LNEEPQLSSAFYF------DLALRSFLTIKEMLQSGAWPKDMEYLNCDDFQGGNTPQRNLDLRDY 362
                 .::.||.:      |::.|.  :..:.|.:.|.|          :..|...:|.|.:
Mouse   310 -----VIAEAFRYLRRQRVDVSRRG--SAGDCLANPAVP----------WSQGIDIERALKM--- 354

  Fly   363 FTKITEPTSYGTFDLVTQSTQPFNGHSFMKFEMDINVLQIRGGSSVNSKSIGKWISGLNSELIVK 427
             .::...|....||...:.|         .:.:|:..:::.|     |:..|.|  ......:..
Mouse   355 -VQVQGMTGNIQFDTYGRRT---------NYTIDVYEMKVSG-----SRKAGYW--NEYERFVPF 402

  Fly   428 DEEQMKNLTADTVYR---IFTVVQAPFIM--RDETAPKG---YKGYCIDLINEIAAIVHFDYTIQ 484
            .::|:.|.::.:..|   :.|::::|::|  ::....:|   |:|||:||..|||..|...|.:.
Mouse   403 SDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLS 467

  Fly   485 EVEDGKFGNMD-ENGQWNGIVKKLMDKQADIGLGSMSVMAEREIVIDFTVPYYDLVGITIMMQRP 548
            .|.|||:|..| |...|||:|.:|:..:|||.:..:::...||.||||:.|:..| ||:||:::|
Mouse   468 IVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSL-GISIMIKKP 531

  Fly   549 -SSPSSLFKFLTVLETNVWLCILAAYFFTSFLMWIFDRWSPYSY--QNNREKYKDDEE----KRE 606
             .|...:|.||..|...:|:||:.||...|.::::..|:|||.:  ::|.|:.:|.:.    ..|
Mouse   532 QKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNE 596

  Fly   607 FNLKECLWFCMTSLTPQGGGEAPKNLSGRLVAATWWLFGFIIIASYTANLAAFLTVSRLDTPVES 671
            |.:...|||.:.:...||...:|::||||:|...||.|..|||:||||||||||||.|:.:|:||
Mouse   597 FGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES 661

  Fly   672 LDDLAKQYKILYAPLNGSSAMTYFERMSNIEQMFYEIWKDLSLNDSLTAVERSKLAVWDYPVSDK 736
            .:|||||.:|.|..|:..|...:|                          .|||:||
Mouse   662 AEDLAKQTEIAYGTLDSGSTKEFF--------------------------RRSKIAV-------- 692

  Fly   737 YTKMWQAMQEAK---LPATLDEAVARVRNSTAATGFAFLGDATDIRYL-QLTNCDLQVVGEEFSR 797
            |.|||..|:.|:   ...|..:.|||||.|...  ||||.::|...|: |...||...||.....
Mouse   693 YEKMWSYMKSAEPSVFTKTTADGVARVRKSKGK--FAFLLESTMNEYIEQRKPCDTMKVGGNLDS 755

  Fly   798 KPYAIAVQQGSHLKDQFNNAILTLLNKRQLEKLKEKWW-KNDEALAKCDKPEDQSDGISIQNIGG 861
            |.|.:|..:||.|:...|.|:|.|..:..|:|||.||| ...|..||....:|::..:|:.|:.|
Mouse   756 KGYGVATPKGSALRTPVNLAVLKLSEQGILDKLKNKWWYDKGECGAKDSGSKDKTSALSLSNVAG 820

  Fly   862 VFIVIFVGIGMACITLVFEYWWYRYR---------KNPRIIDVAEANAERSNAADHPGKLVDG 915
            ||.::..|:|:|.:..:.|: .|:.|         ||.:....|.|...::.|....|..|.|
Mouse   821 VFYILVGGLGLAMMVALIEF-CYKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVYG 882

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.