Protein Alignment Ir25a and grin2da

DIOPT Version :10

• Sequence 1: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: XP_073787594.1
• Gene: grin2da / 449864
• ZFINID: ZDB-GENE-041008-124
• Length: 1918
• Species: Danio rerio
• Alignment Length: 928
• Identity: 192/928 - (20%)
• Similarity: 349/928 - (37%)
• Gaps: 261/928 - (28%)

  Fly    75 IEANKSDAKVLLEAICNKYATS------IEKKQTPHLILDTTKSGIAS--ETVKSFTQALGLPTI 131
            :..|:|....||..:|...||:      .|:::.|    ...::.:|.  |.|.:.|   |:|.|
Zfish   116 LAVNESSPGSLLLQLCELLATTPLQGLVFEEEKPP----PPNRAPLAPMLEFVSAQT---GVPVI 173

  Fly   132 SASYGQQGDLRQWRDLDEAKQKYLLQVMPPADIIPEAIRSIVIHMNITNAAIL------YDD--- 187
            :..    |.....|:..|:...| ||.....|:..|.|..::...:.|..:::      |:|
Zfish   174 AVG----GGAGLGREPQESGSVY-LQFSCSTDLQLEVIFEVLEEFDWTAFSVVTTRHHGYEDFLA 233

  Fly   188 --------SFVMDHKYKSLLQNI-------QTRHVITAIAKDGKREREEQIEKLRNLDINNFFIL 237
                    ||:...:...::.|:       :||.::        :|.|.|
Zfish   234 MVEGMIDGSFIGWERKSVVMLNLTDDPGGARTRRLL--------KENEAQ--------------- 275

  Fly   238 GTLQSIRMVLESVKPA--YFERNFA---------WHAITQNEGEISSQRDNATIMFMKPMAYTQY 291
                 :|::..|.:.|  .|:..:|         |.|:......:..:.....:..::|..:
Zfish   276 -----VRLLYCSQEEAEQIFKAAWASGQATPSHMWFAVGPGLSGLGLEGLPKALFAVRPQGW--- 332

  Fly   292 RDRLGLLRTTYNLNEEPQLSSAFYFDLALRSFLTIKEMLQSGAWPKDMEY---------LNCDDF 347
                         .:||:           |.......:|..||.....||         .||  .
Zfish   333 -------------RDEPR-----------RRIAKGVSVLTHGAMALRREYGGARGTSFAGNC--M 371

  Fly   348 QGGNTPQRNLDLRDYFTKITEPTSYGTFDLVTQSTQPFNGHSFMKFEMDINVLQIRGGSSVNSKS 412
            ..||..||......:|:.||          ::.....||...::...: ::|:....|.  ..:.
Zfish   372 MDGNQTQRVPGRIRFFSNIT----------LSGRDYSFNNDGYLANPL-LDVISYTAGR--GWEE 423

  Fly   413 IGKWISGL---------NSELIVKDEEQMKNLTADTVYRIFTVVQAPFIMRDETAP--------- 459
            :|.|.:|:         .....:|..:..::|      |:.|:.:.||::.:...|
Zfish   424 VGWWENGVLRLRYPPWSRYGPFLKPLDDSQHL------RVVTLEERPFVIVEPADPGTGSCIRDS 482

  Fly   460 ---------------KGY-------KGYCIDLINEIAAIVHFDYTIQEVEDGKFG-NMDENGQWN 501
                           :|.       ||:|||::..:|.||.|.|.:..|.:|:.| |:|  ||||
Zfish   483 VPCRLPLNNRSSMVVEGIQSMKHCCKGFCIDVLKRLAKIVGFTYDLYLVTNGRHGKNID--GQWN 545

  Fly   502 GIVKKLMDKQADIGLGSMSVMAEREIVIDFTVPYYDLVGITIMMQRPSSPSSLFKFLTVLETNVW 566
            |:|.:::.|:||:.:||:::..||..|::|:||:.: .||::|:.|.:...|...||......||
Zfish   546 GMVGEVVSKRADMAIGSLTINEERSEVVEFSVPFVE-TGISVMVSRSNGTVSPSAFLEPYSPAVW 609

  Fly   567 -----LCILAAYFFTSFLMWIFDRWSPYSYQNNREKYKDDEEKREFNLKECLW----FCMTSLTP 622
                 :|:..    .:..::||:.:||..|..:.:..|.....: |.:.:.:|    ....:..|
Zfish   610 VMMFVMCLSV----VAVTVFIFEFFSPVGYNRSLQSGKTAGGSK-FTIGKSIWLLWALVFNNSVP 669

  Fly   623 QGGGEAPKNLSGRLVAATWWLFGFIIIASYTANLAAFLTVSRLDTPVESLDDLAKQYKI-LYAPL 686
            .   |.|:..:.:::...|..|..|.:||||||||||:........|..|.|...|:.. .|.||
Zfish   670 V---ENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEEYIDTVSGLSDKKFQHPTEQYPPL 731

  Fly   687 ------NGSSAMTYFERMSNIEQMFYEIWKDLSLNDSLTAVERSKLAVWDYPVSDKYTKMWQAMQ 745
                  |||:.........|:.|                           |.|.:....:..|::
Zfish   732 RFGTVPNGSTEENIRSNYPNMHQ---------------------------YMVRNNQRGVEDAIE 769

  Fly   746 EAKLPATLDEAVARVRNSTAATGFAFLGDATDIRYLQLTN--CDLQVV--GEEFSRKPYAIAVQQ 806
            ..| ...||               ||:.||..:.|:...:  |.:..:  |:.|:...|.:|:.:
Zfish   770 NLK-TGKLD---------------AFIYDAAVLNYMARKDEGCKVMTIGSGKVFATTGYGVALHK 818

  Fly   807 GSHLKDQFNNAILTLLNKRQLEKLKEKWWKNDEALAKCDKPEDQSDGISIQNIGGVFIVIFVGIG 871
            .|..|...:.|:|.|:...:::.|:..|.   ..:...||.|..|..:.|.|:.|||.::.|.:|
Zfish   819 NSRWKRPLDLALLQLVGDDEIDMLERLWL---SGICHNDKIEVMSSKLDIDNMAGVFYMLLVAMG 880

  Fly   872 MACITLVFE---YWWYRY 886
            ::.:...:|   ||..|:
Zfish   881 LSLLVFAWEHLVYWKLRH 898

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	37..418	CDD:380606	67/394 (17%)
		PBP2_iGluR_putative	438..836	CDD:270435	107/449 (24%)
grin2da	XP_073787594.1	None