Protein Alignment Ir25a and KaiR1D

DIOPT Version :10

• Sequence 1: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: NP_650925.1
• Gene: KaiR1D / 42473
• FlyBaseID: FBgn0038837
• Length: 853
• Species: Drosophila melanogaster
• Alignment Length: 870
• Identity: 237/870 - (27%)
• Similarity: 394/870 - (45%)
• Gaps: 169/870 - (19%)

  Fly    73 DSIEANKSDAKVLLEAICNKYATSIEKKQTPHLILDTTKSGIASETVKSFTQALGLPTISASYGQ 137
            ||..|.|....:|     |....:|...|:.|          .:..|:|....:.:|.:.
  Fly    77 DSFHAGKRVCGLL-----NIGVAAIFGPQSSH----------TASHVQSICDNMEIPHLE----- 121

  Fly   138 QGDLRQWRDLDEAKQKYLLQVMPPADIIPEAIRSIVIHMNITNAAILYDDS--------FVMDH- 193
                .:| |....::..|:.:.|..:.:.:|...||.|.......|:|:::        .:..|
  Fly   122 ----NRW-DYRLRRESCLVNLYPHPNTLSKAYVDIVRHWGWKTFTIIYENNDGIVRLQELLKAHG 181

  Fly   194 ---------------KYKSLLQNIQT---RHVITAIAKDGKREREEQIEKLRNLDINNFFILGTL 240
                           .|:.||:.|:.   .|::.    |...||..::.|
  Fly   182 MTPFPITVRQLSDSGDYRPLLKQIKNSAEAHIVL----DCSTERIHEVLK--------------- 227

  Fly   241 QSIRMVLESVKPAYFERNFAWHAITQNEGEISSQRDNATIMFMKPMAYTQYR----DRLGLLRTT 301
            |:.::.:.|...:|...:...|.:..:|............:..:.:.....|    |..||||:.
  Fly   228 QAQQIGMMSDYHSYLVTSLDLHTVNLDEFRYGGTNITGFRLINEKIVSDVVRQWSIDEKGLLRSA 292

  Fly   302 YNLNEEPQLSSAFY-----FDLALRSFLTIKEMLQSGAWPKDMEYLNCDDFQGGNTPQRNLDLRD 361
             ||......::..|     |..||....|.:::        |:..::||   |.:|.|....|.:
  Fly   293 -NLTTVRSETALMYDAVHLFAKALHDLDTSQQI--------DIHPISCD---GQSTWQHGFSLIN 345

  Fly   362 YFTKITEP---TSYGTFDLVTQSTQPFNGHSFMKFEMDINVLQIRGGSSVNSKSIGKWIS----G 419
            |. ||.|.   |:...||           |...:.:..::::::   :....:.||.|.|    |
  Fly   346 YM-KIVEMKGLTNVIKFD-----------HQGFRTDFMLDIVEL---TPAGIRKIGTWNSTLPDG 395

  Fly   420 LN--SELIVKDEEQMKNLTADTVYRIFTVVQAPFIMRDETA-PKG----YKGYCIDLINEIAAIV 477
            :|  .....|.:|...||...|:. :.|::..|:.||.|:| |..    ::||.:|||:||:..:
  Fly   396 INFTRTFSQKQQEIEANLKNKTLV-VTTILSNPYCMRKESAIPLSGNDQFEGYAVDLIHEISKSL 459

  Fly   478 HFDYTIQEVEDGKFGNMDE-NGQWNGIVKKLMDKQADIGLGSMSVMAEREIVIDFTVPYYDLVGI 541
            .|:|.||.|.||.:|:::: .|:|||::::|::::||:.:..:::..|||..:|||.|:.:| |:
  Fly   460 GFNYKIQLVPDGSYGSLNKLTGEWNGMIRELLEQRADLAIADLTITFEREQAVDFTTPFMNL-GV 523

  Fly   542 TIMMQRP-SSPSSLFKFLTVLETNVWLCILAAYFFTSFLMWIFDRWSPYSYQNNREKYKDDEEKR 605
            :|:.::| ..|.:||.||:.|..:||:.:..||...|.|::|..:::||.:....:.:.:..|.
  Fly   524 SILYRKPIKQPPNLFSFLSPLSLDVWIYMATAYLGVSVLLFILAKFTPYEWPAYTDAHGEKVES- 587

  Fly   606 EFNLKECLWFCMTSLTPQGGGEAPKNLSGRLVAATWWLFGFIIIASYTANLAAFLTVSRLDTPVE 670
            :|.|..|:||.:.||..||....||.||.|:||..||.|..|:|:||||||||||||.|:|:|:|
  Fly   588 QFTLLNCMWFAIGSLMQQGCDFLPKALSTRMVAGIWWFFTLIMISSYTANLAAFLTVERMDSPIE 652

  Fly   671 SLDDLAKQYKILYAPLNGSSAMTYFERMSNIEQMFYEIWKDLSLNDSLTAVERSKLAVWDYPVSD 735
            |.:|||||.:|.|..|.|.|...:|              :|            ||::.
  Fly   653 SAEDLAKQTRIKYGALKGGSTAAFF--------------RD------------SKIST------- 684

  Fly   736 KYTKMWQAMQEAK---LPATLDEAVARVRNSTAATGFAFLGDATDIRYLQLTNCDLQVVGEEFSR 797
             |.:||..|:.|:   ..|:..|.|.||.....:  :|||.::|.|.|:...||:|..||.....
  Fly   685 -YQRMWSFMESARPSVFTASNGEGVERVAKGKGS--YAFLMESTSIEYVTERNCELTQVGGMLDT 746

  Fly   798 KPYAIAVQQGSHLKDQFNNAILTLLNKRQLEKLKEKWWKNDEALAKC----DKPEDQSDGISIQN 858
            |.|.||....|..:...|:.||.|..:.:|..||.||||......||    .|....::.:.:.|
  Fly   747 KSYGIATPPNSPYRTAINSVILKLQEEGKLHILKTKWWKEKRGGGKCRVETSKSSSAANELGLAN 811

  Fly   859 IGGVFIVIFVGIGMACITLVFEYWW 883
            :||||:|:..|:|:||:..|.|:.|
  Fly   812 VGGVFVVLMGGMGVACVIAVCEFVW 836

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	37..418	CDD:380606	68/383 (18%)
		PBP2_iGluR_putative	438..836	CDD:270435	144/407 (35%)
KaiR1D	NP_650925.1	PBP1_iGluR_Kainate	31..400	CDD:380605	71/393 (18%)
		Periplasmic_Binding_Protein_Type_2	415..785	CDD:473866	144/408 (35%)