Protein Alignment Ir25a and Ir93a

DIOPT Version :10

• Sequence 1: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: NP_650924.3
• Gene: Ir93a / 42471
• FlyBaseID: FBgn0259215
• Length: 868
• Species: Drosophila melanogaster
• Alignment Length: 1030
• Identity: 219/1030 - (21%)
• Similarity: 362/1030 - (35%)
• Gaps: 343/1030 - (33%)

  Fly    18 LSLLSSFSLEIAAQTTQNINVLFINE-------VDNEPAAKAVEVVLTYLKK------------- 62
            |.||:...|.|...|..|....|::.       ||:|......|.:|.:.:|
  Fly    12 LLLLAGLQLSILVPTEANDFSSFLSANASLAVVVDHEYMTVHGENILAHFEKILSDVIRENLRNG 76

  Fly    63 --NIRY----GLSVQLDSIEA--------------NKSDAKVLLEAICNKYATSIEKKQTPHLIL 107
              |::|    .:.::.|.:.|              |..:..:||.||.:        ...|.|.|
  Fly    77 GINVKYFSWNAVRLKKDFLAAITVTDCENTWNFYKNTQETSILLIAITD--------SDCPRLPL 133

  Fly   108 DTTKSGIASETVKSFTQALGLPTISASYGQQGDLRQWRDLDEAKQKYLLQ-----VMPPADIIPE 167
            :               :||.:|.:     :.||......|| ||.:.:|.     |.....|:.|
  Fly   134 N---------------RALMVPIV-----ENGDEFPQLILD-AKVQQILNWKTAVVFVDQTILEE 177

  Fly   168 ---AIRSIVIHMNITN-----AAILYD--DSFVMDHKYKSLLQNIQ----TRH--------VITA 210
               .::||| |.:|||     :.|||:  ||.....|..:|.|.:.    .:|        ||:|
  Fly   178 NALLVKSIV-HESITNHITPISLILYEINDSLRGQQKRVALRQALSQFAPKKHEEMRQQFLVISA 241

  Fly   211 IAKDGKREREEQIEKLRNLDINNFFILGTLQSIRMVLESVKPAYFERNFAWHAITQNEGEISSQR 275
            .       .|:.||....|   |.|.:|. |.:..||:.|     .|:|....:|.|..|
  Fly   242 F-------HEDIIEIAETL---NMFHVGN-QWMIFVLDMV-----ARDFDAGTVTINLDE----- 285

  Fly   276 DNATIMFMKPMAYTQYRDRLGLLRTTYNLNE-EPQLSSAFYFDLALRSFLTIKEMLQSGAWPKDM 339
             .|.|.|.                    ||| :|
  Fly   286 -GANIAFA--------------------LNETDP------------------------------- 298

  Fly   340 EYLNCDDFQGGNTPQRNLDLRDYFTKIT--EPTSYGTFDLVTQSTQPFNGHSFMKFEMDINVLQI 402
               ||.|.......:.:|.|.:..:|||  |.:.||..     |.:.:....|.|.|....:|:.
  Fly   299 ---NCQDSLNCTISEISLALVNAISKITVEEESIYGEI-----SDEEWEAIRFTKQEKQAEILEY 355

  Fly   403 R------------------------GGSSVNSK-----------------SIGKWISGLN---SE 423
            .                        |.|..|.|                 :||.|...|.   .|
  Fly   356 MKEFLKTNAKCSSCARWRVETAITWGKSQENRKFRSTPQRDAKNRNFEFINIGYWTPVLGFVCQE 420

  Fly   424 LIVKD-EEQMKNLTADTVYRIFTVVQAPFIMRDETAPKG----YKGYCIDLINEIAAIVHFDYTI 483
            |.... |...:|:|.|    |.||...|:.:..:.: .|    :||..::::.|::..::|.|.:
  Fly   421 LAFPHIEHHFRNITMD----ILTVHNPPWQILTKNS-NGVIVEHKGIVMEIVKELSRALNFSYYL 480

  Fly   484 QEVEDGK---------FGNMDENGQWNG---------IVKKLMDKQADIGLGSMSVMAEREIVID 530
            .|....|         .||  |:.:..|         :|:.:...|..|...:.:|....:...:
  Fly   481 HEASAWKEEDSLSTSAGGN--ESDELVGSMTFRIPYRVVEMVQGNQFFIAAVAATVEDPDQKPFN 543

  Fly   531 FTVPYYDLVGITIMMQRPSSPSSLFKFLTVLETNVWLCILAAYFFTSFLMWIFDRWSPYSYQNNR 595
            :|.| ..:...:.:.::|...|.::.|........|.|::.....|:..::..:|.:|.
  Fly   544 YTQP-ISVQKYSFITRKPDEVSRIYLFTAPFTVETWFCLMGIILLTAPTLYAINRLAPL------ 601

  Fly   596 EKYKDDEEKREFNL---KECLWFCMTSLTPQGGGEAPKNLSGRLVAATWWLFGFIIIASYTANLA 657
                  :|.|...|   |.|.|:...:|..|||...|...|||||...||:...:::.:|..||.
  Fly   602 ------KEMRIVGLSTVKSCFWYIFGALLQQGGMYLPTADSGRLVVGFWWIVVIVLVTTYCGNLV 660

  Fly   658 AFLTVSRLDTPVESLDDLAKQYKIL-YAPLNGSSAMTYFERMSNIEQMFYEIWKDLSLNDSLTAV 721
            ||||..:....|:.|:.|.....|: |...||    |:|||.  ::....|.:|..        :
  Fly   661 AFLTFPKFQPGVDYLNQLEDHKDIVQYGLRNG----TFFERY--VQSTTREDFKHY--------L 711

  Fly   722 ERSKLAVWDYPVSDKYTKMWQAMQEAKLPATLDEAVARVRNSTAATGFAFLGDATDIRY---LQL 783
            ||:|:              :.:.||..:     |||.|             |:..:|.:   |||
  Fly   712 ERAKI--------------YGSAQEEDI-----EAVKR-------------GERINIDWRINLQL 744

  Fly   784 TNCDLQVVGEEFSR-KPYAIAVQQGSHLKDQF------NNAILTLLNKRQLEKLK----EKWWK- 836
                  :|...|.| |....|:.:.|.:.:|.      .:|.|.|:|:......:    |:|.:
  Fly   745 ------IVQRHFEREKECHFALGRESFVDEQIAMIVPAQSAYLHLVNRHIKSMFRMGFIERWHQM 803

  Fly   837 NDEALAKCDKPEDQ----SDGISIQNIGGVFIVIFVGIGMACITLVFEYWWYRYR 887
            |..:..||:....|    :..:::.::.|.|:|:.:|..:|.:.:..|:|:.|:|
  Fly   804 NLPSAGKCNGKSAQRQVTNHKVNMDDMQGCFLVLLLGFTLALLIVCGEFWYRRFR 858

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	37..418	CDD:380606	97/491 (20%)
		PBP2_iGluR_putative	438..836	CDD:270435	96/437 (22%)
Ir93a	NP_650924.3	Periplasmic_Binding_Protein_Type_2	429..>697	CDD:473866	67/291 (23%)
		Lig_chan	574..836	CDD:459656	76/325 (23%)