Protein Alignment Ir25a and Ir76b

DIOPT Version :10

• Sequence 1: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: NP_649176.1
• Gene: Ir76b / 40198
• FlyBaseID: FBgn0036937
• Length: 636
• Species: Drosophila melanogaster
• Alignment Length: 553
• Identity: 111/553 - (20%)
• Similarity: 205/553 - (37%)
• Gaps: 114/553 - (20%)

  Fly   364 TKITEPTSYGTFDLVTQSTQPFNGHSFMKFEMD--INVLQIRGGSSVNSKSIGKWISGLNSELIV 426
            |.:.:....||...||:.....:. |...|:.|  :..|:.........:.:..||.|
  Fly    26 TNLIQMGENGTLSPVTELPMDVDA-SEAGFDADAPVETLETINRKKPKLREMLDWIGG------- 82

  Fly   427 KDEEQMKNLTADTVYRIFTVVQAPFIMRD--ETAPKGYKGYCIDLINEIAAIVHFDYTIQEVEDG 489
                  |:|      ||.|:...|....:  |...:...|....:|:.:....:|.|.:...:|.
  Fly    83 ------KHL------RIATLEDFPLSYTEVLENGTRVGHGVSFQIIDFLKKKFNFTYEVVVPQDN 135

  Fly   490 KFGNMDENGQWNGIVKKLMDKQADIGLGSMSVMAEREIVIDFTVPYYDLVGITIMMQRPSSPSSL 554
            ..|:..:..:  .:::.:.....|:....:..::::...:.::....|.....::||||...:|.
  Fly   136 IIGSPSDFDR--SLIEMVNSSTVDLAAAFIPSLSDQRSFVYYSTTTLDEGEWIMVMQRPRESASG 198

  Fly   555 FKFLTVLETNVWLCILAAYFFTSFLMWIFDRWSPYSYQNNREKYKDDEEKREFNLKECLWFCMTS 619
            ...|...|..||:.||.:......::        |:....|.:...|.::..::|..|.||...:
  Fly   199 SGLLAPFEFWVWILILVSLLAVGPII--------YALIILRNRLTGDGQQTPYSLGHCAWFVYGA 255

  Fly   620 LTPQGGGEAPKNLSGRLVAATWWLFGFIIIASYTANLAAFLTVSRLDTPVESLDDLAKQYKILYA 684
            |..||...:|...|.||:.||||:|..|:.:.|||||.||||:|:...|..:::|:..:.|...:
  Fly   256 LMKQGSTLSPIADSTRLLFATWWIFITILTSFYTANLTAFLTLSKFTLPYNTVNDILTKNKHFVS 320

  Fly   685 PLNGSSAMTYFERMSNIEQMFYEIWKDLSLNDSLTAVERSKLAVWDYPVSDKYTKMWQAMQEAKL 749
            ...|  .:.|..|.:|         :.||:   |..:.::..||:....:|.|
  Fly   321 MRGG--GVEYAIRTTN---------ESLSM---LNRMIQNNYAVFSDETNDTY------------ 359

  Fly   750 PATLDEAVARVRNSTAATGFAFLGDATDIR------YL---------QLTNCDLQVVGEEFSRKP 799
                     .::|.....|:.|:.|...|.      ||         :..:|...:..|.|.:|.
  Fly   360 ---------NLQNYVEKNGYVFVRDRPAINIMLYRDYLYRKTVSFSDEKVHCPFAMAKEPFLKKK 415

  Fly   800 YAIAVQQGSHLKDQFNNAILTLLNKRQLEKLKEKWWKNDEALAKCDKPEDQSDGISIQNIGG--- 861
            ...|...||:|...|:..:|.|:....::.|.::...:.|              |..|::||
  Fly   416 RTFAYPIGSNLSQLFDPELLHLVESGIVKHLSKRNLPSAE--------------ICPQDLGGTER 466

  Fly   862 ---------VFIVIFVGIGMACIT----LVFEY 881
                     .:.::..|...|...    |:|.|
  Fly   467 QLRNGDLMMTYYIMLAGFATALAVFSTELMFRY 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	37..418	CDD:380606	10/55 (18%)
		PBP2_iGluR_putative	438..836	CDD:270435	87/414 (21%)
Ir76b	NP_649176.1	Lig_chan-Glu_bd	83..192	CDD:463166	17/116 (15%)
		Lig_chan	209..458	CDD:459656	69/305 (23%)