Protein Alignment Ir25a and Ir75a

DIOPT Version :9

• Sequence 1: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: NP_649012.2
• Gene: Ir75a / 39982
• FlyBaseID: FBgn0036757
• Length: 629
• Species: Drosophila melanogaster
• Alignment Length: 668
• Identity: 126/668 - (18%)
• Similarity: 211/668 - (31%)
• Gaps: 250/668 - (37%)

  Fly   282 FMKP----MAYTQYRDRLGL-----LRTTYNLNEEPQLSSAFYFDLALRSFLTIKEMLQSGAWPK 337
            ||||    :.|.|:....|:     |..:|..:.:|.|  |.|.|
  Fly    40 FMKPIHPILVYHQFVQMRGVLNWSHLELSYMGHTQPTL--AIYVD-------------------- 82

  Fly   338 DMEYLNCDDFQG--------------------GNTPQRNLDLRDYFTKITEPTSYGTFDLVTQST 382
                :.||..|.                    ||  |..|:..|.|         |.|::...:.
  Fly    83 ----IKCDQTQDLLEEASREQIYNQHYHWLLVGN--QSKLEFYDLF---------GLFNISIDAD 132

  Fly   383 QPFNGHSFMKFEMDINVLQIRGGSSV---------NSKSIG---------------------KWI 417
            .     |::|.::..|      ..||         |.|.||                     :.:
  Fly   133 V-----SYVKEQIQDN------NDSVAYAVHDVYNNGKIIGGQLNVTGSHEMSCDPFVCRRTRHL 186

  Fly   418 SGLNSELIVKDEEQMKNLTADTVYRIFTVV-QAPFIMRDETAPKGYKGYCIDLI--------NEI 473
            |.|.......:.||:    .|.|.|:.||| |.|..:.|:           :||        ..|
  Fly   187 SSLQKRSKYGNREQL----TDVVLRVATVVTQRPLTLSDD-----------ELIRFLSQENDTHI 236

  Fly   474 AAIVHFDYTIQEVEDG------KFGNMDENGQWN------GIVKKLMDKQADI----------GL 516
            .::..|.:.:..:...      ||...|   .|:      |.|..::|:.||:          .|
  Fly   237 DSLARFGFHLTLILRDLLHCKMKFIFSD---SWSKSDVVGGSVGAVVDQTADLTATPSLATEGRL 298

  Fly   517 GSMSVMAE----REIVIDFTVPYYDLVGITIMMQRPSSPSSLFKFLTVLETNVWLCILAAYFFTS 577
            ..:|.:.|    |.:.| |..|:...:...:.:| |.||.            ||...........
  Fly   299 KYLSAIIETGFFRSVCI-FRTPHNAGLRGDVFLQ-PFSPL------------VWYLFGGVLSLIG 349

  Fly   578 FLMWIF---------DRWSPYSYQNNREKYKDDEEKREFNLKECLWFCMTSLTPQGGGEAPKNLS 633
            .|:||.         .||        |..|..       :|.........:...|.....|::..
  Fly   350 VLLWITFYMECKRMQKRW--------RLDYLP-------SLLSTFLISFGAACIQSSSLIPRSAG 399

  Fly   634 GRLVAATWWLFGFIIIASYTANLAAFLTVSRLDTPVESLDDLAK-QYKILYAPLNGSSAMTYFER 697
            |||:....:|..||:...||:.:.:.|..|.:.:.::::..||: ...:...||..:.:...:.|
  Fly   400 GRLIYFALFLISFIMYNYYTSVVVSSLLSSPVKSKIKTMRQLAESSLTVGLEPLPFTKSYLNYSR 464

  Fly   698 MSNIEQMFYEIWKDLSLNDSLTAVERSKLAVWDYPVSDKYTKMWQAMQEAKLPATLDEAVARVRN 762
            :..| .:|               ::|...:....|      ::|       |||  ::.|.|||:
  Fly   465 LPEI-HLF---------------IKRKIESQTQNP------ELW-------LPA--EQGVLRVRD 498

  Fly   763 S-------TAATGFAFLGDATDIRYLQLTN-CDLQVVGEEFSRKP---YAIAVQQGSHLKDQFNN 816
            :       ..::|:|::.     ||..... |||    .|...:|   :...:.:.|..|:.|..
  Fly   499 NPGYVYVFETSSGYAYVE-----RYFTAQEICDL----NEVLFRPEQLFYTHLHRNSTYKELFRL 554

  Fly   817 AILTLLNKRQLEKLKEKW 834
            ..|.:|......|.:..|
  Fly   555 RFLRILETGVYRKQRSYW 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	40..426	CDD:107378	36/202 (18%)
		PBP2_iGluR_putative	438..836	CDD:270435	88/453 (19%)
		Lig_chan	565..870	CDD:278489	55/291 (19%)
Ir75a	NP_649012.2	Lig_chan	337..603	CDD:306551	55/291 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462807
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840