Protein Alignment Ir25a and Ir68b

DIOPT Version :10

• Sequence 1: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: NP_648548.1
• Gene: Ir68b / 39378
• FlyBaseID: FBgn0036250
• Length: 635
• Species: Drosophila melanogaster
• Alignment Length: 832
• Identity: 159/832 - (19%)
• Similarity: 263/832 - (31%)
• Gaps: 300/832 - (36%)

  Fly   139 GDLRQWRDLDEAKQKYLLQVMPPADIIPEAIRSIVIHMNITNAAILY-----DDSFVMDHKYKSL 198
            |.|.||         ||..:...|:|   |.| |.:..|: ....||     ..||..|:   |.
  Fly     6 GLLLQW---------YLPGIYALAEI---ACR-IAVEQNV-QVTYLYRCASCPASFDADY---SA 53

  Fly   199 LQNIQTRHVITAIAKDGKREREEQIEKLRNLDINNFFILGTLQS----IRMVLESVKPAYFERNF 259
            |:....|.|.:.:....:.....::|..|..|..:.|.:...:.    :|.:|:.:.|  .:|..
  Fly    54 LELDLYRCVGSRLPVITRNMEAHELEPFRRTDSLSIFQIPAAEKGDSLVRRILDMLNP--HQRRK 116

  Fly   260 AWHAITQNEGEISSQRDNATIMFMKPMAYTQYRDRLGLLRTTYNLNEEPQLSSAFYFDLALRSFL 324
            ..|                ..:|:.|.|     .|..|||
  Fly   117 HMH----------------KYLFVWPNA-----GRHQLLR------------------------- 135

  Fly   325 TIKEMLQSGAWPKDMEYLNCDDFQG-GNTPQRNLDLRDYFTKITEPTSYGTFDLVTQSTQPFNGH 388
                 |..|:|.|.:.|       | ..|.:.|                ||||.     .||
  Fly   136 -----LFRGSWAKKLLY-------GLAITGREN----------------GTFDF-----DPF--- 164

  Fly   389 SFMKFEMDINVLQIRGGSSVNSKSIGKWISGLNSELIVKDEEQMKNLTADTV-YRIFT-----VV 447
                         ..||..|        |..|:.|  |....::|:|....: :.:||     :.
  Fly   165 -------------AWGGLQV--------IQRLDGE--VPYARKVKDLRGYPLRFSMFTDPLMAMP 206

  Fly   448 QAPFIMRDETAPKGYK---GYCIDLINEI--AAIVHFDYTIQEVEDGKFGNMDENGQWNGIVKKL 507
            ::|.    |||  ||:   |....::.|:  |::.   |...| ::..:|....||.:.|:|
  Fly   207 RSPV----ETA--GYQAVDGVAARVVGEMLNASVT---YVFPE-DNESYGRCLPNGNYTGVV--- 258

  Fly   508 MDKQADIGLGSMSVMAEREIVIDFTVP----YYDLVGITIMMQRPSS---PSSLFKFLTVLETNV 565
                :||..|..........|:|...|    .|......:.:..|:|   |..|. |:.|....|
  Fly   259 ----SDIVGGHTHFAPNSRFVLDCIWPAVEVLYPYTRRNLHLVVPASAIQPEYLI-FVRVFRRTV 318

  Fly   566 WLCILAAYFFTSFLMWIFDRWSPYSYQNNREKYKDDEEKR-------EFNLKECLWFCMTSLTPQ 623
            |..:|........:.|:..|.                ::|       :|   :..|:.:..:..:
  Fly   319 WYLLLVTLLVVVLVFWVMQRL----------------QRRIPRRGVIQF---QATWYEILEMFGK 364

  Fly   624 GG-GEAPKNLSG----RLVAATWWLFGFIIIASYTANLAAFLTVSRLDTPVESLDDLAKQYKILY 683
            .. ||....||.    |.....|.||.:::...|.|.|.:.......:..|:.:|||......:|
  Fly   365 THVGEPAGRLSSFSSMRTFLMGWILFSYVLSTIYFAKLESGFVRPSYEEQVDRVDDLVHLDVHIY 429

  Fly   684 APLNGSSAMTYFERMSNIEQMFYEIWKDLSLNDSLTAVERSKLAVWDYPVSDKYTKMWQAMQEAK 748
            |                :..|:..:              ||.|....|.:.:..::        :
  Fly   430 A----------------VTTMYDAV--------------RSALTEHQYGLLENRSR--------Q 456

  Fly   749 LP----ATLDEAVARVRNSTAATGFAFLGDATDIRYLQLTNCDLQVVGEEFSRKPYAIAVQQGSH 809
            ||    .:..:.|.|.|:..||   ..:.|.....:|.:|      ...:..|..|.||
  Fly   457 LPLGIATSYYQPVVRRRDRRAA---FIMRDFHARDFLAIT------YDSQAERPAYHIA------ 506

  Fly   810 LKDQFNNAILTLLNKR------QLEKLK---------EKWWKND---------------EALAKC 844
             ::...:.|.|.:..|      :||.|.         |.|.:.|               |.|...
  Fly   507 -REYLRSMICTYILPRGSPFLHRLESLYSGFLEHGFFEHWRQMDLITRVGASPDAEEFLEDLGDQ 570

  Fly   845 DKPEDQSDGISIQN---------IGGVFIVIFVGIGMACITLVFE--YWWYR 885
            ...:..|:.::|:|         :.|.|.:..||||::|:....|  :|::|
  Fly   571 TDTDSGSNELAIRNKKVVLTLDILQGAFYLWSVGIGISCLGFAVEHAHWFWR 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	37..418	CDD:380606	54/288 (19%)
		PBP2_iGluR_putative	438..836	CDD:270435	83/446 (19%)
Ir68b	NP_648548.1	None