Protein Alignment Ir25a and Ir68a

DIOPT Version :10

• Sequence 1: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Alignment Length: 578
• Identity: 108/578 - (18%)
• Similarity: 217/578 - (37%)
• Gaps: 138/578 - (23%)

  Fly   390 FMKFEMD----INVLQIRG--GSSVNSKSIGKWI--SGLNSELIVKDEEQMKNLTADTVYRIFTV 446
            |:|.::|    |:.:...|  ...:..|:|..|.  .|||..::..|  :..||.. |...:...
  Fly   168 FLKRQLDNKYTISTIAFPGILSGVLVMKNIANWELGKGLNGRILFAD--KTSNLFG-TSLPVAIS 229

  Fly   447 VQAPFIMRDETAPKGYKGYCIDLINEIAAIVHF-------------DYTIQEVEDGK-----FGN 493
            ...|.::. ..|.|.::|..::::|.:...::|             |:|  |::.|.     .||
  Fly   230 EHVPMVLW-ANATKSFQGVEVEIMNALGKALNFKPVYYKPNQTENMDWT--ELDGGASVAYGSGN 291

  Fly   494 MDENGQWNG------IVKKLMDKQADIGLGSMSVMAEREIVIDFTVPYYDLVGITIMMQRPSSPS 552
            .|...| ||      :|.::....|...:|.:.:......:::.:.| ::...:|.:....|:.:
  Fly   292 PDGYAQ-NGTHIDSMLVDEVAAHSARFAIGDLHLFQVYLKLVELSAP-HNFECLTFLTPESSTDN 354

  Fly   553 SLFKFLTVLETNVWLCILAAYFFT-------SFLMWIFD-----------------RWSPYSYQ- 592
            |...|:......:|:.:|.:.|..       |||..|.:                 ...|..|:
  Fly   355 SWQTFILPFSAGMWVGVLLSLFVVGTVFYAISFLNAIINGNVSSEFFRCLRPNRNVPMDPKIYRR 419

  Fly   593 -------NNREKYKDDEEKREF--NLKECLWFCMTSLTPQGGGEAPKNLSGRLVAATWWLFGFII 648
                   :.....|.|...|:.  ....|:....:.|........|:|...|::...:|::..::
  Fly   420 ISFRIAISRYRSSKGDRMPRDLFDGYTNCILLTYSMLLYVALPRMPRNWPLRVLTGWYWIYCILL 484

  Fly   649 IASYTANLAAFLTVSRLDTPVESLDDLAKQYKILYAPLNGSSAMTYFERMSNIEQMFYEIWKDLS 713
            :|:|.|:..|.|........:::|:||.:.:   ..|..|::.          .:.|:     |.
  Fly   485 VATYRASFTAILANPAARVTIDTLEDLLRSH---IPPSTGATE----------NRQFF-----LE 531

  Fly   714 LNDSLTAVERSKLAVWDYPVSDKYTKMWQAMQEAKLPATLDEAVARVRNSTAATGFAFLGDATDI 778
            .||.:......|:.|:.|.                     |:..:|:.....    |:..:...:
  Fly   532 ANDEVARKVGEKMEVFGYS---------------------DDLTSRIAKGQC----AYYDNEFYL 571

  Fly   779 RYLQL---TNCDLQVVGEEFSRKPYAIAVQQGSHLKDQFNNAILTLLNKRQLEKLKEKWWKN--- 837
            |||::   :...|.::.|.....|..:|:::.|.||.:.:.:|..|..    ..|..||.|:
  Fly   572 RYLRVADESGSALHIMKECVLYMPVVLAMEKNSALKPRVDASIQHLAE----GGLIAKWLKDAIE 632

  Fly   838 ---DEALAKCDKPEDQSDGISIQNIGGVFIVIFVGIGMACITLVFEYWWYRY--RKNP 890
               .||||:      |...::||.....|:.:.:|..::.:||:.|.|.:::  .|:|
  Fly   633 HLPAEALAQ------QEALMNIQKFWSSFVALLIGYVISMLTLLAERWHFKHIVMKHP 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	37..418	CDD:380606	8/35 (23%)
		PBP2_iGluR_putative	438..836	CDD:270435	78/458 (17%)
Ir68a	NP_648455.2	Lig_chan	367..661	CDD:459656	62/346 (18%)