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Protein Alignment Ir25a and Gria3

DIOPT Version :9

Sequence 1:	NP_001260049.1	Gene:	Ir25a / 33683	FlyBaseID:	FBgn0031634	Length:	947	Species:	Drosophila melanogaster
Sequence 2:	NP_001106213.1	Gene:	Gria3 / 29628	RGDID:	70958	Length:	888	Species:	Rattus norvegicus

Alignment Length:	976	Identity:	255/976 - (26%)
Similarity:	426/976 - (43%)	Gaps:	213/976 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 TQNINVLFINEVDNEPAAKAVEVVLTYLKKNIR---YGLSVQLDSIEANKSDAKVLLEAICNKYA 94
            |.:|..||:.....|.:|....|.|....:|..   :.|:..:|.::::.|.:  :..|.|::::
  Rat    27 TISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFS--VTNAFCSQFS 89

  Fly    95 TSIEKKQTPHLILDTTKSGIASETVKSFTQALGLPTISASYGQQGDLRQWRDLDEAKQKYLLQVM 159
            ..:      :.|...... ::..|:.||..||....::.|:....|:           ::::|:.
  Rat    90 RGV------YAIFGFYDQ-MSMNTLTSFCGALHTSFVTPSFPTDADV-----------QFVIQMR 136

  Fly   160 PPADIIPEAIRSIVIHMNITNAAILYDDSFVMDHKYKSLLQNI-----QTRHVITA--------- 210
            |   .:..||.|::.:........|||     ..:..|:||.|     |....:||
  Rat   137 P---ALKGAILSLLGYYKWEKFVYLYD-----TERGFSVLQAIMEAAVQNNWQVTARSVGNIKDV 193

  Fly   211 -----IAKDGKREREE------QIEKLRNLDINNFFILG-----------TLQSIRMVLESVKPA 253
                 |.::..|.:|:      ::|:: |..:....|||           .|....::||.|  .
  Rat   194 QEFRRIIEEMDRRQEKRYLIDCEVERI-NTILEQVVILGKHSRGYHYMLANLGFTDILLERV--M 255

  Fly   254 YFERNFAWHAITQNEGEISSQ---------------RDNATIMFMKPMAYTQYRDRLGLLRTTYN 303
            :...|.....|..||..:..|               ..||      |:.||.......:|
  Rat   256 HGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNA------PLKYTSALTHDAIL----- 309

  Fly   304 LNEEPQLSSAFYF------DLALRSFLTIKEMLQSGAWPKDMEYLNCDDFQGGNTPQRNLDLRDY 362
                 .::.||.:      |::.|.  :..:.|.:.|.|          :..|...:|.|.:
  Rat   310 -----VIAEAFRYLRRQRVDVSRRG--SAGDCLANPAVP----------WSQGIDIERALKM--- 354

  Fly   363 FTKITEPTSYGTFDLVTQSTQPFNGHSFMKFEMDINVLQIRGGSSVNSKSIGKWISGLNSELIVK 427
             .::...|....||...:.|         .:.:|:..:::.|     |:..|.|  ......:..
  Rat   355 -VQVQGMTGNIQFDTYGRRT---------NYTIDVYEMKVSG-----SRKAGYW--NEYERFVPF 402

  Fly   428 DEEQMKNLTADTVYR---IFTVVQAPFIM--RDETAPKG---YKGYCIDLINEIAAIVHFDYTIQ 484
            .::|:.|.::.:..|   :.|::::|::|  ::....:|   |:|||:||..|||..|...|.:.
  Rat   403 SDQQISNDSSSSENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLS 467

  Fly   485 EVEDGKFGNMD-ENGQWNGIVKKLMDKQADIGLGSMSVMAEREIVIDFTVPYYDLVGITIMMQRP 548
            .|.|||:|..| |...|||:|.:|:..:|||.:..:::...||.||||:.|:..| ||:||:::|
  Rat   468 IVGDGKYGARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSL-GISIMIKKP 531

  Fly   549 -SSPSSLFKFLTVLETNVWLCILAAYFFTSFLMWIFDRWSPYSY--QNNREKYKDDEE----KRE 606
             .|...:|.||..|...:|:||:.||...|.::::..|:|||.:  ::|.|:.:|.:.    ..|
  Rat   532 QKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPPNE 596

  Fly   607 FNLKECLWFCMTSLTPQGGGEAPKNLSGRLVAATWWLFGFIIIASYTANLAAFLTVSRLDTPVES 671
            |.:...|||.:.:...||...:|::||||:|...||.|..|||:||||||||||||.|:.:|:||
  Rat   597 FGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIES 661

  Fly   672 LDDLAKQYKILYAPLNGSSAMTYFERMSNIEQMFYEIWKDLSLNDSLTAVERSKLAVWDYPVSDK 736
            .:|||||.:|.|..|:..|...:|                          .|||:||
  Rat   662 AEDLAKQTEIAYGTLDSGSTKEFF--------------------------RRSKIAV-------- 692

  Fly   737 YTKMWQAMQEAK---LPATLDEAVARVRNSTAATGFAFLGDATDIRYL-QLTNCDLQVVGEEFSR 797
            |.|||..|:.|:   ...|..:.|||||.|...  ||||.::|...|: |...||...||.....
  Rat   693 YEKMWSYMKSAEPSVFTKTTADGVARVRKSKGK--FAFLLESTMNEYIEQRKPCDTMKVGGNLDS 755

  Fly   798 KPYAIAVQQGSHLKDQFNNAILTLLNKRQLEKLKEKWWKNDEALAKCDK----PEDQSDGISIQN 858
            |.|.:|..:||.|.:..|.|:|.|..:..|:|||.|||.:.   .:|..    .:|::..:|:.|
  Rat   756 KGYGVATPKGSALGNAVNLAVLKLNEQGLLDKLKNKWWYDK---GECGSGGGDSKDKTSALSLSN 817

  Fly   859 IGGVFIVIFVGIGMACITLVFEYWWYRYR---------KNPRIIDVAEANAERSNAADHPGKLVD 914
            :.|||.::..|:|:|.:..:.|: .|:.|         ||.:....|.|...::.|....|..|.
  Rat   818 VAGVFYILVGGLGLAMMVALIEF-CYKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVY 881

  Fly   915 G 915
            |
  Rat   882 G 882

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.