Protein Alignment Ir25a and glr-8

DIOPT Version :9

• Sequence 1: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: NP_001368711.1
• Gene: glr-8 / 180924
• WormBaseID: WBGene00001619
• Length: 547
• Species: Caenorhabditis elegans
• Alignment Length: 553
• Identity: 114/553 - (20%)
• Similarity: 216/553 - (39%)
• Gaps: 94/553 - (16%)

  Fly   398 NVLQIRGGSSVNSKSIGKWISGLNSE----LIVKDEE--QMKNLTADTVYRIFTVVQAPFI---- 452
            |:|:     |:|.|......:.|.|:    ..:.:|:  .:..:...|:..:...::.|::
 Worm    21 NILE-----SINEKVAHPPQTSLTSDYGDAYTLSNEKHFSLSEMKGRTLKMVVPAIEPPYVNYVN 80

  Fly   453 MRD-ETAPKGY-KGYCIDLINEIAAIVHFDYTIQEVEDGKFGNMDENGQWNGIVKKLMDKQADIG 515
            ..| ....||| .|..::::.||...::..|.|.......:|.. .||.|.|...:|:..:.|:.
 Worm    81 FSDAAVTDKGYGPGVVMEILKEIGKRLNLTYEILPALGSTWGEY-LNGSWTGAFGQLVRGEVDLL 144

  Fly   516 LGSMSVMAEREIVIDFTVPY-YDLVGITIMMQRPSSPSSLFKFLTVLETNVWLCILAAYFFTSFL 579
            .|...:..:|.::.|.|.|: ::..||.|.........:|..........||: |.||....|.:
 Worm   145 AGGAIMEYDRSVIADLTYPFQFEPTGIMIRSPEKYEDDTLLIVTEPFSWEVWV-ITAAVILISGV 208

  Fly   580 MWIFDRWSPYSYQNNREKYKDDEEKREFNLKECLWFCMTSLTPQGGGEAPKNLSGRLVAATWWLF 644
            :::.       ..|...|..::.....|   |.:|...:....||..|.|::.|.|::.|.|||.
 Worm   209 IFLV-------MTNIIRKVYEEMTVTPF---ESIWVFFSIFVQQGLPEQPRSWSCRVLVALWWLA 263

  Fly   645 GFIIIASYTANLAAFLTVSRLDTPVESLDDLAKQYKILYAPLNGSSAMTYFERMSNIEQMFYEIW 709
            ...:.|::|.:|.|...|.:.:.|.:::|.|.:.                      ::|..:||.
 Worm   264 SITLSATFTGSLVALFAVDKTNVPFQNIDQLVRL----------------------VKQGKFEIV 306

  Fly   710 KDLSLNDSLTAVE---RSKLAVWDYPVSDKYTKMWQAM---QEAKLPATLDEAVARVRNSTAATG 768
            .|   .:|.|..|   ||||.|        |..:|..|   .:.|....:...||.||   |..|
 Worm   307 MD---ENSFTRTEMIARSKLPV--------YRDLWHEMIVNHKVKYVNGIARGVAFVR---ANPG 357

  Fly   769 FAFLGDATDIRYLQLTNCDLQVVGEEFSRKPYAIAVQQGSHLKDQFNNAILTLLNKRQLEKLKEK 833
            :|.||....:.:...::|.:.:..:.......:|.:.:.|.....|:..|..::.:    ...:|
 Worm   358 YALLGPMATLNFYAYSDCKVILFNDGILPVYLSIPLVKNSIYSPYFSTKIREMVER----GFTQK 418

  Fly   834 W---WKNDEALAKCDKPEDQSDG----ISIQNIGGVFIVIFVGIGMACITLVFEYWWYRYRKN-- 889
            |   :::..|:.|.::....:.|    :.::...|.|.|...|.|:.....|.|:.:..:|:.
 Worm   419 WIADYRSYVAMQKINECNSTTIGPKSYLDLKRAQGAFWVFLGGAGLGLALFVGEFIFKFFREKMT 483

  Fly   890 ---------PRIIDVAEANAERSNAADHPGKLV 913
                     |.:..|:...||.|.:.|.|.:::
 Worm   484 KHTKTTTVPPEVATVSANVAENSTSLDIPDEVL 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	40..426	CDD:107378	7/31 (23%)
		PBP2_iGluR_putative	438..836	CDD:270435	88/413 (21%)
		Lig_chan	565..870	CDD:278489	67/317 (21%)
glr-8	NP_001368711.1	PBP2_iGluR_ligand_binding	62..424	CDD:270219	88/413 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810