Protein Alignment Ir25a and glr-7

DIOPT Version :10

• Sequence 1: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: NP_001337310.1
• Gene: glr-7 / 180547
• WormBaseID: WBGene00001618
• Length: 885
• Species: Caenorhabditis elegans
• Alignment Length: 909
• Identity: 383/909 - (42%)
• Similarity: 538/909 - (59%)
• Gaps: 99/909 - (10%)

  Fly    70 VQLDSIEANKSDAKVLLEAICNKYATSIEKKQTPHLILDTTKSGIASETVKSFTQALGLPTISAS 134
            :.|:..:.|.|..   :.::|::..       ....::...:|..:...|....:...:|||
 Worm    12 ISLERYDFNDSSD---INSLCDQMV-------NVSFVISVCRSNDSISLVAELARISQVPTI--- 63

  Fly   135 YGQQGDLRQWR-DLD--------EAKQKYLLQVMPPADIIPEAIRSIVIHMNIT-NAAILYDDSF 189
               |.||..|. .|:        .:...|...|:... :....|..|...:||| |:.:|||:.:
 Worm    64 ---QVDLNYWSLPLNFNGTSVPTISSPSYTTMVLSTL-VFQNVITDIFADLNITPNSTVLYDNMY 124

  Fly   190 VMD----HKYKSLLQNIQTRHVITAIAKDGKREREEQIEKLRNLDINNFFILGTLQSI-RMVLES 249
            ..|    ....|:|..|:...:.|.:.:     ...||.:||...||:..::...::: |..||:
 Worm   125 PPDFTAWRDAFSVLPGIRFVPMETTVLR-----MRAQITQLRMASINSLILVAKTENVERFTLEA 184

  Fly   250 VKPAYF--ERNFAWHAITQNEGEISSQRDNATIMF-MKPMAYTQ-----------YRDRLGLLRT 300
               |.|  :|.|..:.:|::..........:..|| ::|....:           :|:.:| |..
 Worm   185 ---ADFIEQRVFNTYVLTKDITAFKCDSCESAFMFWLRPFPVGKLMEIRDLDDYLFRNEIG-LEL 245

  Fly   301 TYNLNEEPQLSSAFYFDLALRSFLTIKEMLQSGAWPKDMEYLNCDDFQGGNTPQRNLDLRDYFTK 365
            .|::|....|:.|||.::...:|.||:.|   .|....:....|.  .|.:.|.....:||..
 Worm   246 DYSINGWDSLNVAFYMNVMGYAFETIRTM---NATFDVLPTFTCQ--TGPSEPNITTTVRDII-- 303

  Fly   366 ITEPT-SYGTFDLVTQSTQPFNGHSFMKFEMDINVLQIRGG----SSVNSKSIGKW--ISGLNSE 423
            :.:|. .||.:   |::     |.:....::::.:.:|...    .::.:|.:|.|  ||.| |.
 Worm   304 LNDPAHEYGNY---TEA-----GLNMFFQDVEVRIYKIDRDRDHEDALFNKEVGVWSPISKL-SV 359

  Fly   424 LIVKDEEQMKNLTADTVYRIFTVVQAPFIMRDETAPKGYKGYCIDLINEIAAIVHFDYTIQEVED 488
            :....:..::||   .::|:.|::|.||:.|.......|:||||||||.|...|:|.|||.||||
 Worm   360 MYGTLQVDVRNL---NIFRVVTLIQPPFVQRTGDPDTPYEGYCIDLINMIQVEVNFTYTIYEVED 421

  Fly   489 GKFGNMDENGQWNGIVKKLMDKQADIGLGSMSVMAEREIVIDFTVPYYDLVGITIMMQRPSSPSS 553
            |.||.||:||.|||::..|:...|||.|..:|||||||..:|||||||||||.||:|::.....|
 Worm   422 GSFGTMDDNGNWNGLIGALVSGSADIALAPLSVMAERENDVDFTVPYYDLVGTTILMKKADVEYS 486

  Fly   554 LFKFLTVLETNVWLCILAAYFFTSFLMWIFDRWSPYSYQNNREKYKDDEEKREFNLKECLWFCMT 618
            ||||:.|||..|||||:|||.|||.|:|||||:||||:.||:|:|::|.|||:|:||||||||||
 Worm   487 LFKFMKVLEWPVWLCIVAAYLFTSILLWIFDRFSPYSFTNNKERYQNDIEKRQFSLKECLWFCMT 551

  Fly   619 SLTPQGGGEAPKNLSGRLVAATWWLFGFIIIASYTANLAAFLTVSRLDTPVESLDDLAKQYKILY 683
            |||||||||||||:|||||||||||||||||||||||||||||||||:.|:.|||||||||||.|
 Worm   552 SLTPQGGGEAPKNISGRLVAATWWLFGFIIIASYTANLAAFLTVSRLEQPISSLDDLAKQYKIEY 616

  Fly   684 APLNGSSAMTYFERMSNIEQMFYEIWKDLSLNDSLTAVERSKLAVWDYPVSDKYTKMWQAMQEAK 748
            ||:.||::.|||.||:.||:.||.:||::|||:|::..:|:||||||||||||:|.||:.|||:|
 Worm   617 APIKGSASETYFRRMAEIEETFYNMWKEMSLNESMSPRDRAKLAVWDYPVSDKFTNMWRYMQESK 681

  Fly   749 LPATLDEAVARVRNSTAATGFAFLGDATDIRYLQLTNCDLQVVGEEFSRKPYAIAVQQGSHLKDQ 813
            ||..:|.||.||.||  ..||||:||||:|:|..||||:||.||.||||||||||||.|..|||:
 Worm   682 LPVNMDTAVDRVLNS--VDGFAFIGDATEIKYAALTNCNLQQVGTEFSRKPYAIAVQSGHILKDK 744

  Fly   814 FNNAILTLLNKRQLEKLKEKWWKNDEALAKCDKPEDQSDGISIQNIGGVFIVIFVGIGMACITLV 878
            .::|||.|||:|:||.||||||.::.....|....|:||||||||||||||||..||.::.:||.
 Worm   745 ISSAILMLLNERRLETLKEKWWTDNPNKVSCPDSSDESDGISIQNIGGVFIVILAGIALSIVTLA 809

  Fly   879 FEYWWYRYR------KNPRIIDVAEA-----NAERSNAA--DHPGKLVDGVILGHSGEKFEKSK 929
            |||::|:.:      |....:::.::     |...:|..  |.| ||.:|.  ..:|..|.::|
 Worm   810 FEYYYYKRKARKAAEKEQEELEMKQSQQVVPNGFHTNGVKQDAP-KLTNGT--KTNGNTFRRTK 870

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	37..418	CDD:380606	75/383 (20%)
		PBP2_iGluR_putative	438..836	CDD:270435	264/397 (66%)
glr-7	NP_001337310.1	Periplasmic_Binding_Protein_type1	<101..>274	CDD:471960	43/181 (24%)
		PBP2_iGluR_putative	373..767	CDD:270435	264/395 (67%)