Protein Alignment Ir25a and Grin2d

DIOPT Version :9

• Sequence 1: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: XP_036008580.1
• Gene: Grin2d / 14814
• MGIID: 95823
• Length: 1345
• Species: Mus musculus
• Alignment Length: 632
• Identity: 145/632 - (22%)
• Similarity: 249/632 - (39%)
• Gaps: 169/632 - (26%)

  Fly   346 DFQGGNTPQRNLDLRDYFTKIT-EPTSYGTFDLVTQSTQPFNGHSFMKFEMDINVLQIRGGSSVN 409
            |.:..|...|...|..||..|| :...|.           ||...|:   ::.:::.|.......
Mouse   349 DCRAQNRTHRGESLHRYFMNITWDNRDYS-----------FNEDGFL---VNPSLVVISLTRDRT 399

  Fly   410 SKSIGKWISGLNSELIVKDEEQMKNL--------------TADTVY-RIFTVVQAPFI------- 452
            .:.:|.|            |:|...|              ..||.: .:.|:.:.||:
Mouse   400 WEVVGSW------------EQQTLRLKYPLWSRYGRFLQPVDDTQHLTVATLEERPFVIVEPADP 452

  Fly   453 -----MRDE-------------TAPKG------------YKGYCIDLINEIAAIVHFDYTIQEVE 487
                 :||.             .||:.            .||:|||::..:|..:.|.|.:..|.
Mouse   453 ISGTCIRDSVPCRSQLNRTHSLVAPRSPPPDAPRPEKRCCKGFCIDILKRLAHTIGFSYDLYLVT 517

  Fly   488 DGKFGNMDENGQWNGIVKKLMDKQADIGLGSMSVMAEREIVIDFTVPYYDLVGITIMMQRPS--- 549
            :||.|...: |.|||::.::..::||:.:||:::..||..::||:||:.: .||::|:.|.:
Mouse   518 NGKHGKKID-GVWNGMIGEVFYQRADMAIGSLTINEERSEIVDFSVPFVE-TGISVMVARSNGTV 580

  Fly   550 SPSSLFKFLTVL--------ETNVW-----LCILAAYFFTSFLMWIFDRWSPYSYQNNREKYKDD 601
            |||:...|..::        ...||     :|:..    .:..::||:..||..|..:....|..
Mouse   581 SPSAFLAFAWLMPPMSPEPYSPAVWVMMFVMCLTV----VAVTVFIFEYLSPVGYNRSLATGKRP 641

  Fly   602 EEKREFNLKECLW----FCMTSLTPQGGGEAPKNLSGRLVAATWWLFGFIIIASYTANLAAFLTV 662
            ... .|.:.:.:|    ....:..|.   |.|:..:.:::...|..|..|.:||||||||||:..
Mouse   642 GGS-TFTIGKSIWLLWALVFNNSVPV---ENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQ 702

  Fly   663 SRLDTPVESLDDLAKQY-KILYAPL------NGSSAMTYFERMSNIEQMFYEIWKDLSLNDSLTA 720
            ......|..|.|...|. :..|.||      |||:.       .||..
Mouse   703 EEYVDTVSGLSDRKFQRPQEQYPPLKFGTVPNGSTE-------KNIRS----------------- 743

  Fly   721 VERSKLAVWDYPVSDKYTKMWQAMQEAKLPATLDEAVARVRNSTAATGFAFLGDATDIRYLQLTN 785
                     :||  |.::.|.:..|     ..::||:.:::   |....||:.||..:.|:...:
Mouse   744 ---------NYP--DMHSYMVRYNQ-----PRVEEALTQLK---AGKLDAFIYDAAVLNYMARKD 789

  Fly   786 --CDLQVV--GEEFSRKPYAIAVQQGSHLKDQFNNAILTLLNKRQLEKLKEKWWKNDEALAKCDK 846
              |.|..:  |:.|:...|.||:.:||..|...:.|:|..|...::|.|:..|.   ..:...||
Mouse   790 EGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGDDEIEMLERLWL---SGICHNDK 851

  Fly   847 PEDQSDGISIQNIGGVFIVIFVGIGMACITLVFE---YWWYRYRKNP 890
            .|..|..:.|.|:.|||.::.|.:|::.:...:|   ||..|:...|
Mouse   852 IEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLVYWRLRHCLGP 898

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	40..426	CDD:107378	15/80 (19%)
		PBP2_iGluR_putative	438..836	CDD:270435	111/466 (24%)
		Lig_chan	565..870	CDD:278489	78/324 (24%)
Grin2d	XP_036008580.1	Periplasmic_Binding_Protein_type1	<156..415	CDD:415822	18/91 (20%)
		PBP2_iGluR_NMDA_Nr2	432..849	CDD:270436	109/472 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846648
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740