Protein Alignment Ir25a and grin3b

DIOPT Version :9

• Sequence 1: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: XP_017952374.2
• Gene: grin3b / 100497172
• XenbaseID: XB-GENE-990106
• Length: 1005
• Species: Xenopus tropicalis
• Alignment Length: 975
• Identity: 196/975 - (20%)
• Similarity: 365/975 - (37%)
• Gaps: 259/975 - (26%)

  Fly    65 RYGLSVQLDSIEANKSDAKVLLEAICNKYATSIEKKQTPH-LILDTTKSGIASETVKSFTQ---- 124
            |.|.:|:|.::..:....:..::.:.::.:.:   ...|: |.|:.........:..|.|:
 Frog    32 RIGHTVRLGALLPSYGHTQARIQNVLSRISRT---SWLPYNLSLEVVSGAPRDRSPASLTRWLCQ 93

  Fly   125 ---ALGLPTISASYGQQGDLRQWRDLDEAKQKYLLQVMPPADIIPEAIRSIVIHMNI-TNAAI-- 183
               |.|:..:.|....|.:|.|...|....:...:.::....|:|.|.:: ..|:.: |.:::
 Frog    94 VLVAQGIAAVLAFPQAQEELLQLEFLSSFLEIPFISILEQEQIVPLATKN-PFHLQMDTQSSVEN 157

  Fly   184 LYDDSFVMDHKYKSLLQNIQTRHV--ITAIAKDGKREREEQIEKLRNLDINNFFILGTLQSIRMV 246
            |.|..|       |:|||.....|  ||....|....:       |.|..|...:..|:.:|..|
 Frog   158 LMDIFF-------SVLQNSSWEEVDIITCHPWDSASIQ-------RYLTSNTTLVSRTILNIHPV 208

  Fly   247 LESVKPAYFERNFA-------------------------------------W---HAITQNE--- 268
            .||....:.:::|.                                     |   |.:...|
 Frog   209 DESALVPFLQQHFESMKNPQFPMLLYGCDARRSSLVFRVARDCGLEAHEFHWMIGHPLNGEEMTT 273

  Fly   269 ----------GEISSQRDNATIMFMKPMAYTQYRDRLGLLRTTYNLNEEPQLSSAFYF--DLALR 321
                      ||:|           :|......||.:||:...        :|:|.:.  ||||
 Frog   274 EGMPPGLLAYGEVS-----------RPTMEKFIRDAVGLVTRA--------ISAAVHVRPDLAL- 318

  Fly   322 SFLTIKEMLQSGAWPKDMEYLNCDDFQGGNTPQRNLDLRDYFTKITEPTSYGTFDLVTQSTQPFN 386
                    :||        .:||:|.|    .::|.....|.::....||:.     .|:.|.:.
 Frog   319 --------IQS--------MVNCNDKQ----TKQNESSGSYLSRFLANTSFS-----GQTGQIYV 358

  Fly   387 GHSFMKFEMDINVLQIRGGSSVNSK--SIGKWISGLNS------ELIVKDEEQMKNLTADTVYRI 443
            .::.:..|....:..:...|..:..  ::|.|..|...      :..::..|......|.|..|:
 Frog   359 SNNLIHTEHHYRIWSLVRDSLGDPTWVTVGGWRQGKMEVEEGLWQSRIQQWEPAPGGFARTKLRV 423

  Fly   444 FTVVQAPFIMRDE-------------------------------TAPKG-----YK----GYCID 468
            .|:|:.||:...|                               .:|.|     ||    |||||
 Frog   424 VTLVEHPFVFTREVDADGSCPAGQMCLDPRTNNSAVLDVLFEELNSPNGSVPLEYKTCCYGYCID 488

  Fly   469 LINEIAAIVHFDYTIQEVEDGKFGNMDENGQWNGIVKKLMDKQADIGLGSMSVMAEREIVIDFTV 533
            |:.:::..:.||:.:..|.|||:| ..:..:|.|:|..|:...|.:.:.|.|:.:.|..|||||.
 Frog   489 LLEKLSEDLRFDFELYIVGDGKYG-ARKGDRWTGLVGDLLSGAAHMAVTSFSINSARSTVIDFTS 552

  Fly   534 PYYDL-VGITIMMQRPSSPSSLFKFLTVLETNVWLCILAAYFFTSFLMWIFDRWSPYS---YQNN 594
            |:|.. :||.:.|:..:||  :..|:..|..::|:.|..|...|:..:..::..||:.   :..|
 Frog   553 PFYSTSLGILVRMRDTASP--IGAFMWPLHWSMWVGIFVALHITALFLTFYEWKSPFGMTPHGRN 615

  Fly   595 REKYKDDEEKREFNLKECLWFCMTSLTPQG-GGEAPKNLSGRLVAATWWLFGFIIIASYTANLAA 658
            |.|.        |:....|..|...|..:. ..:.||..:||::...|.:|..::::||||||||
 Frog   616 RTKI--------FSYSSALNLCYAILFGRTVSSKTPKCCTGRVLMNLWAIFCLLVLSSYTANLAA 672

  Fly   659 FLTVSRLDTPVESLDDLAKQYKILYAPLNGSSAMTYFERMSNIEQMFYEIWKDLSLNDSLTAVER 723
            .:...:....:..:.|     ..|:.|..|....|.:|  |:.||.
 Frog   673 VMVGDKTFEALSGIHD-----PKLHHPSQGFRFGTVWE--SSAEQY------------------- 711

  Fly   724 SKLAVWDYPVSDKYTKMWQAMQEAKLPATLDEAVARVRNSTAATGFAFLGDATDIRY-LQL-TNC 786
                     :...:.:|...|::..:|||.|.  ..:..:...|..||:.|...:.| :.: ::|
 Frog   712 ---------IKKSFPEMHNYMRKFSVPATSDG--VHLLKTDPPTLNAFIMDKALLDYEVSIDSDC 765

  Fly   787 DLQVVGEEFSRKPYAIAVQQGSHLKDQFNNAILTLLNKRQLEKLKEKWWKNDEALAKCDK---PE 848
            .|..:|:.|:.:.|.|.:.|.|.|....:..|....:...::.|.:||:|    :..|.|   ..
 Frog   766 KLLTIGKPFAIEGYGIGLPQNSPLTSNISEFISRYKSSGFMDTLHDKWYK----MVPCGKRVYAV 826

  Fly   849 DQSDGISIQNIGGVFIVIFVGIGMACITLV------------------FEYWWYRYRKNPRIIDV 895
            .::..:.|.:..|:|:::.:|...:.:|.:                  |:||.:..:|..|.:::
 Frog   827 TETLQMGIYHFSGLFVLLCIGFCGSLLTSLMERVVYHLILPRIRRRRRFKYWLHTSQKIHRALNM 891

  Fly   896  895
             Frog   892  891

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	40..426	CDD:107378	75/436 (17%)
		PBP2_iGluR_putative	438..836	CDD:270435	106/444 (24%)
		Lig_chan	565..870	CDD:278489	66/313 (21%)
grin3b	XP_017952374.2	PBP1_iGluR_NMDA_NR3	29..402	CDD:380600	75/432 (17%)
		PBP2_iGluR_NMDA_Nr3	418..814	CDD:270438	105/443 (24%)
		Lig_chan	582..848	CDD:395014	66/314 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910