Protein Alignment Ir25a and si:ch211-264f5.8

DIOPT Version :10

• Sequence 1: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: XP_017207885.1
• Gene: si:ch211-264f5.8 / 100331381
• ZFINID: ZDB-GENE-081104-209
• Length: 1063
• Species: Danio rerio
• Alignment Length: 955
• Identity: 250/955 - (26%)
• Similarity: 402/955 - (42%)
• Gaps: 231/955 - (24%)

  Fly    30 AQTTQNINVLFINEVDNEPAAKAVEVVLTYLKKNIRYGLSVQLDSI----------EANKSDAKV 84
            |...:|||.|.     ..||...|||.:..|:::.:|..:..:..|          .|:...:..
Zfish    57 ALARENINSLM-----EGPARARVEVDIFELQRDSQYETTDTMCQILPKGVVSVIGPASSPASGS 116

  Fly    85 LLEAICNKYATSIEKKQTPHLILDTTKS------GIASET-----------VKSFTQALGLPTIS 132
            .:..||.       :|:.||:.:...::      ..||.|           :.:..::.|.||.|
Zfish   117 TVSHICG-------EKEIPHIKIGPEETPRLPYLRFASVTLYPSNEDLSLAIGAILRSFGYPTAS 174

  Fly   133 ASYGQQGDLRQWRDLDEAKQKYLLQVMPPADIIPEAIRSIVIHMNITNAAILYDDSFVMDHKYKS 197
                          |..||.:.||:       :.|.:|..:|.....:..:|.::   :|.  ..
Zfish   175 --------------LICAKAECLLR-------LEELVRHFLISRETLSVRMLDEN---LDP--TP 213

  Fly   198 LLQNIQTRHVITAIAKDGKREREEQIEKLRNLDINNFF---ILGTLQSIRMVLESV--------- 250
            ||:.|:...|.|.|...........::|...|.:.:.|   ||.|:....:.|:.|
Zfish   214 LLKEIRDDKVATIIIDANASVSILILKKASELGMTSAFYKYILTTMDFPLLRLDDVVNDQSNIVG 278

  Fly   251 -------KPAYFE----RNFAWHAITQNEGEISSQRDNATIMFMKPMAYTQYRDRLGLLRTTYNL 304
                   .|.|.|    .|.:|                                |.|...:.|
Zfish   279 FSMLNNSHPFYLEFIRSLNLSW--------------------------------REGCDLSPY-- 309

  Fly   305 NEEPQLSSAFYFDLALRSFLTIKEMLQS---GAWPKDMEYLNCDD---FQGGNTPQRNLDLRDYF 363
             ..|.||||..||........::|:.:|   |..|     |:|..   :|.|.:....|.:.:|
Zfish   310 -PGPALSSALMFDAVHVVVGAVRELNRSQEIGVKP-----LSCTSSLIWQHGTSLMNYLRMVEY- 367

  Fly   364 TKITEPTSYGTFDLVTQSTQPFNGHSFMKFEMDINVLQ-IRGGSSVNSKSIGKWIS----GLNS- 422
                        |.:|...: ||... .:....:.:|: .:||    .|.||.|.|    .:||
Zfish   368 ------------DGLTGRVE-FNSKG-QRTNYTLRILEKFKGG----HKEIGVWYSNNTLAMNST 414

  Fly   423 ELIVKDEEQMKNLTADTVYRIFTVVQAPFIMRDET-----APKGYKGYCIDLINEIAAIVHFDYT 482
            .|.:...|.:.|.|    ..:.|:::.|::||.|.     ....|:|:|:|::.|:|.|:.|.:.
Zfish   415 SLDINTSETLANKT----LTVTTILENPYVMRKENYQDFQGSDQYEGFCVDMLRELADILKFSFR 475

  Fly   483 IQEVEDGKFGNMDENGQWNGIVKKLMDKQADIGLGSMSVMAEREIVIDFTVPYYDLVGITIMM-- 545
            |:.|:||.:|..:.||.|.|:|.:|::::||:.:...::.:|||.||||:.|:.:| ||:|:.
Zfish   476 IKLVDDGLYGAPEPNGSWTGMVGELINRKADLAVAGFTITSEREKVIDFSKPFMNL-GISILYRV 539

  Fly   546 ---QRPSSPSSLFKFLTVLETNVWLCILAAYFFTSFLMWIFDRWSPYSYQNNREKYKD--DEEKR 605
               ::|    ..|.||......|||.:|.||...|.::::..|.|||.:.|....:::  |..:.
Zfish   540 HIGRKP----GYFSFLDPFSPAVWLFMLLAYLAVSCVLFLAARLSPYEWYNPFPCWRERRDLLEN 600

  Fly   606 EFNLKECLWFCMTSLTPQGGGEAPKNLSGRLVAATWWLFGFIIIASYTANLAAFLTVSRLDTPVE 670
            ::.|...|||.:.....||....|:.||.|.|:..||.|..|||:||||||||||||.|::.|:|
Zfish   601 QYTLGNSLWFPIGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEVPIE 665

  Fly   671 SLDDLAKQYKILYAPLNGSSAMTYFERMSNIEQMFYEIWKDLSLNDSLTAVERSKLAVWDYPVSD 735
            |.:|||.|..|.|..:.|.|.||:|                  :|......:|    :|:|
Zfish   666 SAEDLADQTNIQYGTIQGGSTMTFF------------------MNSRYQTYQR----MWNY---- 704

  Fly   736 KYTKMWQAMQEAKLPATLDEAVARVRNSTAATGFAFLGDATDIRYLQLTNCDLQVVGEEFSRKPY 800
            .|:|     |.:....:.:|.:|||.||.    :|||.::|...|.:..||:|..:|.....|.|
Zfish   705 MYSK-----QPSVFVKSTEEGIARVLNSK----YAFLLESTMNEYHRRLNCNLTQIGGLLDTKGY 760

  Fly   801 AIAVQQGSHLKDQFNNAILTLLNKRQLEKLKEKWWKNDEALAKCDKPED-QSDGISIQNIGGVFI 864
            .|.:..||..:|:....||.|....:||.||.:||:.    .||.|.|| ::.|:.:.||||:|:
Zfish   761 GIGMPLGSPFRDEITLGILQLQENNRLEILKRRWWEG----GKCLKEEDHRAKGLGMDNIGGIFV 821

  Fly   865 VIFVGIGMACITLVFEYWWYRYRKNPRIIDVAEANAERSNAADHP 909
            |:..|:.:|....:.|:.|...|           :||......||
Zfish   822 VLICGLIIAVFVAIMEFVWSTRR-----------SAETDEVRPHP 855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	37..418	CDD:380606	83/437 (19%)
		PBP2_iGluR_putative	438..836	CDD:270435	135/409 (33%)
si:ch211-264f5.8	XP_017207885.1	PBP1_iGluR_Kainate_KA1_2	35..413	CDD:380616	87/452 (19%)
		Periplasmic_Binding_Protein_Type_2	426..796	CDD:473866	137/413 (33%)