Protein Alignment Ir25a and LOC100149482

DIOPT Version :9

• Sequence 1: NP_001260049.1
• Gene: Ir25a / 33683
• FlyBaseID: FBgn0031634
• Length: 947
• Species: Drosophila melanogaster
• Sequence 2: XP_009290417.1
• Gene: LOC100149482 / 100149482
• -ID: -
• Length: 1959
• Species: Danio rerio
• Alignment Length: 998
• Identity: 210/998 - (21%)
• Similarity: 375/998 - (37%)
• Gaps: 257/998 - (25%)

  Fly    18 LSLLSSFSLEIAAQTTQNINVLF-INEVDNEPAAKA-VEVVLTYLKKNIRYGL------------ 68
            ||||.:. :|.|.||:.:.::|. ..|.:.:|.|.. ..:.:.:....::.|.
Zfish     7 LSLLLAL-VEWAGQTSSSPHLLLRPRERERDPVASMHFNIAVIHAGSTVQQGEAGAAAAAGRVPY 70

  Fly    69 -------------------SVQLDSIEANKSDAKVLLEAICNKYATS-----IEKKQTPHLILDT 109
                               |..:..::.|.|..:.||..:|:..|..     :.:.:.| |.|.|
Zfish    71 PGFGRVHSSFGESVVTQWGSANVIWLQVNDSSPRTLLSQLCDLLAARPLQGLVYEDERP-LPLAT 134

  Fly   110 TKSGIASETVKSFTQALGLPTISASYG--------QQGDL-RQWRDLDEAKQKYLLQVMPPADII 165
            .......|.|.:.|   |||.::...|        :.|.: .|:......:.:.:.:|:...|..
Zfish   135 GPLAPMLEFVSAQT---GLPIVAVGGGAALGRVPQESGSIFLQFSSSTALQLEVIFEVLEEYDWT 196

  Fly   166 PEAIRSIVIH-----MNITNAAILYDDSFVMDHKYKSLLQN-------IQTRHVITAIAKDGKRE 218
            ..::.|...|     :::...  |.|.||:...|...::.|       ::|:.::        :|
Zfish   197 AFSVVSTRHHGYQDFLSVVEG--LTDGSFIGWEKKSIVMLNLTDDPGGVRTQRLL--------KE 251

  Fly   219 REEQIEKLRNLDINNFFILGTLQSIRMVLESVKPAYFERNF--AWHAITQNEGEISSQRDNATIM 281
            .|.|                    :|::..|.:.|  |:.|  ||.|         .|...:.|.
Zfish   252 NEAQ--------------------VRLLYCSQEEA--EQVFLAAWAA---------GQAGASHIW 285

  Fly   282 F-----MKPMAYTQYRDRLGLLRTTYNLNEEPQLSSAFYFDLALRSFLTIKEMLQSGAWPKDMEY 341
            |     :..:..|....||..:| .....:||:...|....:.....:.:::  ..||.......
Zfish   286 FAVGPALSELGLTGLPKRLFAVR-PQGWRDEPRRRIARGVSILTHGAVALRK--DYGATGGPHFV 347

  Fly   342 LNCDDFQGGNTPQRNLDLRDYFTKITEPTSYGTFDLVTQSTQPFNGHSFMKFEMDINVLQIRGGS 406
            .||.  ..||..||......||:.||......:|........||           ::|:....||
Zfish   348 TNCQ--TDGNRTQRIRGRMRYFSNITLGGRDYSFSNEGYLANPF-----------LDVISYTPGS 399

  Fly   407 SVNSKSIGKWISGL-----------NSELIVKDEEQMKNLTADTVYRIFTVVQAPFI-------- 452
              ..:.:|.|.:|:           ...|...|:.|.        .|:.|:.:.||:
Zfish   400 --GWEDVGWWENGVLRLRYPAWSRYGPFLQPPDDAQH--------LRVVTLEERPFVIVELADAA 454

  Fly   453 -------------------MRDETAP--KGYKGYCIDLINEIAAIVHFDYTIQEVEDGKFGNMDE 496
                               :::..||  :..||:|||::..:|.||.|.|.:..|.:||.|...:
Zfish   455 SGTCIRDSVPCRRPLNASALQEGVAPVKQCCKGFCIDILKRLARIVGFTYDLYLVTNGKHGKKID 519

  Fly   497 NGQWNGIVKKLMDKQADIGLGSMSVMAEREIVIDFTVPYYDLVGITIMMQRPSSPSSLFKFLTVL 561
             |.|||:|.:::.|:||:.:||:::..||..|:||:||:.: .||::|:.|.:...|...||...
Zfish   520 -GVWNGMVGEVVYKRADMAIGSLTINEERSEVVDFSVPFVE-TGISVMVSRSNGTVSPSAFLEPY 582

  Fly   562 ETNVW-----LCILAAYFFTSFLMWIFDRWSPYSYQNNREKYKDDEEKREFNLKECLW----FCM 617
            ...||     :|:..    .:..::||:.:||..|..:.:..|.....: |.:.:.:|    ...
Zfish   583 SPAVWVMMFVMCLTV----VAVTVFIFEFFSPVGYNRSLQSGKKAGGSK-FTIGKSIWLLWALVF 642

  Fly   618 TSLTPQGGGEAPKNLSGRLVAATWWLFGFIIIASYTANLAAFLTVSRLDTPVESLDDLAKQYKI- 681
            .:..|.   |.||..:.:::...|..|..|.:||||||||||:........|..|.|...|:..
Zfish   643 NNSVPV---ENPKGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEEYIDTVSGLSDKKFQHPTE 704

  Fly   682 LYAPL------NGSSAMTYFERMSNIEQMFYEIWKDLSLNDSLTAVERSKLAVWDYPVSDKYTKM 740
            .|.||      |||:.........::.|...: :...|:.|:::.::..||.
Zfish   705 QYPPLKFGTVPNGSTEKNIRSNYPDMHQYMVK-YNQKSVEDAISHLKTGKLD------------- 755

  Fly   741 WQAMQEAKLPATLDEAVARVRNSTAATGFAFLGDATDIRYLQLTN--CDLQVV--GEEFSRKPYA 801
                                         ||:.||..:.|:...:  |.:..:  |:.|:...|.
Zfish   756 -----------------------------AFIYDAAVLNYMARKDEGCKVMTIGSGKVFATTGYG 791

  Fly   802 IAVQQGSHLKDQFNNAILTLLNKRQLEKLKEKWWKNDEALAKCDKPEDQSDGISIQNIGGVFIVI 866
            ||:.:.|..|...:.|:|.|:...::|.|:..|.   ..:...||.|..|..:.|.|:.|||.::
Zfish   792 IALIKNSRWKRPLDLALLQLVGDDEIEMLERLWL---SGICHNDKIEVMSSKLDIDNMAGVFYML 853

  Fly   867 FVGIGMACITLVFE---YWWYRY 886
            .|.:|::.:...:|   ||..|:
Zfish   854 LVAMGLSLLVFAWEHLVYWRLRH 876

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir25a	NP_001260049.1	PBP1_iGluR_AMPA_Like	40..426	CDD:107378	78/462 (17%)
		PBP2_iGluR_putative	438..836	CDD:270435	106/446 (24%)
		Lig_chan	565..870	CDD:278489	72/324 (22%)
LOC100149482	XP_009290417.1	PBP1_iGluR_NMDA_NR2	44..421	CDD:107373	74/439 (17%)
		PBP2_iGluR_NMDA_Nr2	433..831	CDD:270436	107/461 (23%)
		HisJ	<487..>570	CDD:223904	34/84 (40%)
		Lig_chan	585..857	CDD:278489	72/325 (22%)
		NMDAR2_C	868..>900	CDD:287527	3/9 (33%)
		FAM76	<1763..>1856	CDD:292665

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591786
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.830