DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fnta and cwp1

DIOPT Version :9

Sequence 1:	NP_001260048.1	Gene:	Fnta / 33682	FlyBaseID:	FBgn0031633	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_593518.1	Gene:	cwp1 / 2543143	PomBaseID:	SPAPB1A10.04c	Length:	294	Species:	Schizosaccharomyces pombe

Alignment Length:	302	Identity:	104/302 - (34%)
Similarity:	167/302 - (55%)	Gaps:	31/302 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 SDWEDVQPLAQDDGPNPVVSIAYSQKFREVFDYMRAIIARGEKSQRALDLTTDALRLNPANYTVW 85
            :::..:.|:.||||.||:..|.|:..:.:...|.|||:|:.|.|.|||:||...:..|||:||||
pombe    15 TEYGPLTPIPQDDGENPLAKICYTTGYEQGMAYFRAIMAKKEYSLRALNLTGFLIMNNPAHYTVW 79

  Fly    86 QYRRDVLRELKADLYAELDYLTEVIGQNSKNYQVWHHRRVIVEMLNDPSNELELTENALVNDGDA 150
            .||..:|....:.:..||::|.|:.....|||||||||:.|:.:..:...|||.|:...  :.|:
pombe    80 AYRFQILNHTPSYIDNELEWLDEIAEDFQKNYQVWHHRQKILSLTKNYERELEFTKKMF--EIDS 142

  Fly   151 KNYHAWQHRQWAIRSFNLYDDELSFVDRLISEDQRNNSAWNQRFFVIKHFGFTPELI----QREL 211
            ||||.|.:|.|.:::||.|..||...:.|:.:|..||||||.||:|:..   |.:::    :.||
pombe   143 KNYHVWSYRVWILQNFNDYSQELKLTNELLEKDIYNNSAWNHRFYVLFE---TSKVVSWSLEEEL 204

  Fly   212 SYTMNRIRIIKNNESAWNYLVGVMRQGDSGNALLSSYPDVVDFVEELYQAGNRSPYLLAFLIDLY 276
            :|..::|....:|:||||||.||:.:  ||.:.|.:.  :.:..:.|  .....| ||.||. :|
pombe   205 NYLKDKILFAPDNQSAWNYLCGVLDK--SGPSKLDNL--IANLRKNL--PALHKP-LLEFLA-MY 261

  Fly   277 QEQALQLKASDSDQLARKVYGLCEDMATKHDVIRRKYWQYVA 318
            :       .|.|:::.:|       :|.:.||.....|.:::
pombe   262 E-------PSSSEEIYQK-------LANEVDVPHAALWTWMS 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fnta	NP_001260048.1	PLN02789	14..314	CDD:215423	103/296 (35%)
cwp1	NP_593518.1	BET4	9..294	CDD:227823	104/302 (34%)
		PPTA	96..122	CDD:279565	14/25 (56%)
		PPTA	130..157	CDD:279565	12/28 (43%)
		PPTA	164..190	CDD:279565	13/25 (52%)
		PPTA	203..230	CDD:279565	13/26 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	41	1.000	Domainoid score	I3714
eggNOG	1	0.900	-	-		E1_COG5536
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1534
Inparanoid	1	1.050	176	1.000	Inparanoid score	I1158
OMA	1	1.010	-	-		QHG54481
OrthoFinder	1	1.000	-	-		FOG0005243
OrthoInspector	1	1.000	-	-		oto101669
orthoMCL	1	0.900	-	-		OOG6_102620
Panther	1	1.100	-	-	LDO	PTHR11129
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R453
SonicParanoid	1	1.000	-	-		X3760
TreeFam	1	0.960	-	-
	14	13.860