DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fnta and FNTA

DIOPT Version :9

Sequence 1:	NP_001260048.1	Gene:	Fnta / 33682	FlyBaseID:	FBgn0031633	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_002018.1	Gene:	FNTA / 2339	HGNCID:	3782	Length:	379	Species:	Homo sapiens

Alignment Length:	327	Identity:	157/327 - (48%)
Similarity:	233/327 - (71%)	Gaps:	14/327 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 DEEYLGTD---WLAYSERSDWEDVQPLAQDDGPNPVVSIAYSQKFREVFDYMRAIIARGEKSQRA 67
            |:.::..|   ::.|.:|::|.|:.|:.|:|||||||.|.||.|||:|:||.||::.|.|:|:||
Human    52 DDGFVSLDSPSYVLYRDRAEWADIDPVPQNDGPNPVVQIIYSDKFRDVYDYFRAVLQRDERSERA 116

  Fly    68 LDLTTDALRLNPANYTVWQYRRDVLRELKADLYAELDYLTEVIGQNSKNYQVWHHRRVIVEMLND 132
            ..||.||:.||.||||||.:||.:|:.|:.||:.|::|:|.:|.:..|||||||||||:||.|.|
Human   117 FKLTRDAIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQVWHHRRVLVEWLRD 181

  Fly   133 PSNELELTENALVNDGDAKNYHAWQHRQWAIRSFNLYDDELSFVDRLISEDQRNNSAWNQRFFVI 197
            ||.|||...:.|  :.|||||||||||||.|:.|.|:|:||.:||:|:.||.||||.||||:|||
Human   182 PSQELEFIADIL--NQDAKNYHAWQHRQWVIQEFKLWDNELQYVDQLLKEDVRNNSVWNQRYFVI 244

  Fly   198 KH-FGFTPE-LIQRELSYTMNRIRIIKNNESAWNYLVGVMRQGDSGNALLSSYPDVVDFVEELYQ 260
            .: .|:... :::||:.||:..|:::.:||||||||.|:::  |.|   ||.||::::.:.:| |
Human   245 SNTTGYNDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQ--DRG---LSKYPNLLNQLLDL-Q 303

  Fly   261 AGNRSPYLLAFLIDLYQEQALQLKASDSDQLARKVYGLCEDMATKHDVIRRKYWQYVANHLKNQL 325
            ..:.||||:|||:|:| |..|:.:..:.:.:..|...|||.:|.:.|.||::||:|:...|:::.
Human   304 PSHSSPYLIAFLVDIY-EDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSKH 367

  Fly   326 ST 327
            ||
Human   368 ST 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fnta	NP_001260048.1	PLN02789	14..314	CDD:215423	149/301 (50%)
FNTA	NP_002018.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..54		1/1 (100%)
		PLN02789	64..365	CDD:215423	153/309 (50%)
		PFTA 1	112..146		19/33 (58%)
		PFTA 2	147..180		19/32 (59%)
		PFTA 3	181..215		22/35 (63%)
		PFTA 4	216..249		19/32 (59%)
		PFTA 5	255..289		16/38 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145878
Domainoid	1	1.000	75	1.000	Domainoid score	I9101
eggNOG	1	0.900	-	-		E1_COG5536
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1534
Inparanoid	1	1.050	328	1.000	Inparanoid score	I2470
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54481
OrthoDB	1	1.010	-	-		D1527547at2759
OrthoFinder	1	1.000	-	-		FOG0005243
OrthoInspector	1	1.000	-	-		oto90770
orthoMCL	1	0.900	-	-		OOG6_102620
Panther	1	1.100	-	-	LDO	PTHR11129
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3760
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.770