DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fnta and Fnta

DIOPT Version :9

Sequence 1:	NP_001260048.1	Gene:	Fnta / 33682	FlyBaseID:	FBgn0031633	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_032059.1	Gene:	Fnta / 14272	MGIID:	104683	Length:	377	Species:	Mus musculus

Alignment Length:	324	Identity:	157/324 - (48%)
Similarity:	230/324 - (70%)	Gaps:	14/324 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 DEEYLGTD---WLAYSERSDWEDVQPLAQDDGPNPVVSIAYSQKFREVFDYMRAIIARGEKSQRA 67
            |:.:|..|   ::.|.:|::|.|:.|:.|:|||||||.|.||:|||:|:||.||::.|.|:|:||
Mouse    52 DDGFLSLDSPTYVLYRDRAEWADIDPVPQNDGPNPVVQIIYSEKFRDVYDYFRAVLQRDERSERA 116

  Fly    68 LDLTTDALRLNPANYTVWQYRRDVLRELKADLYAELDYLTEVIGQNSKNYQVWHHRRVIVEMLND 132
            ..||.||:.||.||||||.:||.:||.|:.||..|::|:|.:|.:..|||||||||||:||.|.|
Mouse   117 FKLTRDAIELNAANYTVWHFRRVLLRSLQKDLQEEMNYITAIIEEQPKNYQVWHHRRVLVEWLKD 181

  Fly   133 PSNELELTENALVNDGDAKNYHAWQHRQWAIRSFNLYDDELSFVDRLISEDQRNNSAWNQRFFVI 197
            ||.|||...:.|  ..|||||||||||||.|:.|.|:|:||.:||:|:.||.||||.||||.|||
Mouse   182 PSQELEFIADIL--SQDAKNYHAWQHRQWVIQEFRLWDNELQYVDQLLKEDVRNNSVWNQRHFVI 244

  Fly   198 KH-FGFTPE-LIQRELSYTMNRIRIIKNNESAWNYLVGVMRQGDSGNALLSSYPDVVDFVEELYQ 260
            .: .|::.. :::||:.||:..|:::.:||||||||.|:::  |.|   ||.||::::.:.:| |
Mouse   245 SNTTGYSDRAVLEREVQYTLEMIKLVPHNESAWNYLKGILQ--DRG---LSRYPNLLNQLLDL-Q 303

  Fly   261 AGNRSPYLLAFLIDLYQEQALQLKASDSDQLARKVYGLCEDMATKHDVIRRKYWQYVANHLKNQ 324
            ..:.||||:|||:|:| |..|:.:..:.:.:..|...|||.:|.:.|.||::||:|:...|:::
Mouse   304 PSHSSPYLIAFLVDVY-EDMLENQCDNKEDILNKALELCEILAKEKDTIRKEYWRYIGRSLQSK 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fnta	NP_001260048.1	PLN02789	14..314	CDD:215423	150/301 (50%)
Fnta	NP_032059.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..55		1/2 (50%)
		PPTA	64..365	CDD:332411	152/302 (50%)
		PFTA 1	112..146		20/33 (61%)
		PFTA 2	147..181		20/33 (61%)
		PFTA 3	182..214		19/31 (61%)
		PFTA 4	215..249		20/34 (59%)
		PFTA 5	255..289		16/33 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835956
Domainoid	1	1.000	77	1.000	Domainoid score	I8861
eggNOG	1	0.900	-	-		E1_COG5536
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1534
Inparanoid	1	1.050	325	1.000	Inparanoid score	I2469
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54481
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005243
OrthoInspector	1	1.000	-	-		oto94353
orthoMCL	1	0.900	-	-		OOG6_102620
Panther	1	1.100	-	-	LDO	PTHR11129
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R453
SonicParanoid	1	1.000	-	-		X3760
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790