Protein Alignment CG3225 and DHX38

DIOPT Version :10

• Sequence 1: NP_608860.1
• Gene: CG3225 / 33680
• FlyBaseID: FBgn0031631
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_054722.2
• Gene: DHX38 / 9785
• HGNCID: 17211
• Length: 1227
• Species: Homo sapiens
• Alignment Length: 682
• Identity: 277/682 - (40%)
• Similarity: 410/682 - (60%)
• Gaps: 40/682 - (5%)

  Fly    12 ETDDAITDSAGGE---------------QQSSAFVFNVNHNMGLMEQRERLPIRQYRDQILYCLE 61
            |.|.|:|:....:               :.||.|.    ....::|||:.|||...:.::|..:.
Human   486 EPDKAVTEDGKVDYRTEQKFADHMKRKSEASSEFA----KKKSILEQRQYLPIFAVQQELLTIIR 546

  Fly    62 KHQVVILVGETGSGKSTQVPQYLYEWGWHTKGLIGITEPRRVSTVTLANRVAQERGELVGDTVGY 126
            .:.:||:||||||||:||:.|||:|.|:...|:||.|:||||:.:::|.||::|.|..:|:.|||
Human   547 DNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEEMGGNLGEEVGY 611

  Fly   127 VVRFLESMSSCTKIKFMTEGILLREVLADPLLTQYGVIIVDEAHERNMLTDMILGLLKKILRKRS 191
            .:||.:..|..|.||:||:||||||.|.:..|..|..||:||||||::.||::.|||::::.:||
Human   612 AIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRS 676

  Fly   192 SLKLIISSATIDASFFSEFFSWPGSGEVSVKLSIEGRMHPVSNFYLNEPCADYVKETVETVWKLH 256
            .||||::|||:||..|:.||     |.|.: ..|.||..||...:...|..|||:..|:...::|
Human   677 DLKLIVTSATMDAEKFAAFF-----GNVPI-FHIPGRTFPVDILFSKTPQEDYVEAAVKQSLQVH 735

  Fly   257 QKEPPGDILAFLTGQEEVLEALDLLREYIASSEQEN---LKVLPMYGSMSSTDQLSVFFTPPKGT 318
            ....|||||.|:.|||::....|.:.|::  .|.||   |.|||:|..:.|..|..:|...|.|.
Human   736 LSGAPGDILIFMPGQEDIEVTSDQIVEHL--EELENAPALAVLPIYSQLPSDLQAKIFQKAPDGV 798

  Fly   319 RKVVLATNIAETSITIPGIVYVIDCGYVKVKWYNPKTCSDSLVIVPVSKASAIQRAGRAGRMRPG 383
            ||.::||||||||:|:.||::|||.||.|:|.:||:...|:|.|.|:|:|:|.||:|||||..||
Human   799 RKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPG 863

  Fly   384 KVYRLYTKSDYE-ALAPRQPPEMRRSELSGAILQLKALGIGNILRFDFPSPPPAQNLLSALESLF 447
            :.:||||:|.|: .|.....||::|:.|:..:|.||:||:.::|:|.|..|||..|:|:::..|:
Human   864 QCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQFHFMDPPPEDNMLNSMYQLW 928

  Fly   448 ALDAIDEQGNLTKPVGYLLAELPFSAMLSKMLYVSGQMGCSEEIITIIALLQVQSIFSRPASAVA 512
            .|.|:|..|.||. .|.|:.|.|....|||||.||..||||.||:.|:::|.|.:||.||... .
Human   929 ILGALDNTGGLTS-TGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRPKGR-E 991

  Fly   513 QQSGRIAHRKFEVAEGDFITMLNAYTGFVEEGMTKEFCGQYFLIYRNLKRAHSLREQL--ITVAR 575
            ::|.:| ..||.|.|.|.:|.||.|..:.....:..:|..:|:..:.:::...:|.||  |.|.:
Human   992 EESDQI-REKFAVPESDHLTYLNVYLQWKNNNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQ 1055

  Fly   576 KKYGIPIFSCKGDVEKLCKCITAGFFTQVAYLHHSGVYRQISSGTELAIHPNSTLYTLPQA-QYV 639
            :   :.:.||..|.:.:.|||.|.:|.|.|.|...|.|..|.:|....:||.|:|:.:... .|:
Human  1056 R---MSLASCGTDWDIVRKCICAAYFHQAAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYI 1117

  Fly   640 VYGELLQTTKLFMNYVTVIKREWLTELAPHYY 671
            ||.||:.|||.:|..||.:..|||.||.|.:|
Human  1118 VYHELVMTTKEYMQCVTAVDGEWLAELGPMFY 1149

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3225	NP_608860.1	HrpA	38..>669	CDD:441249	268/637 (42%)
DHX38	NP_054722.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	60..320
		HrpA	532..>1146	CDD:441249	265/627 (42%)
		DEAH box	652..655		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1155..1227