Protein Alignment CG3225 and PRP22

DIOPT Version :9

• Sequence 1: NP_608860.1
• Gene: CG3225 / 33680
• FlyBaseID: FBgn0031631
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_010929.3
• Gene: PRP22 / 856732
• SGDID: S000000815
• Length: 1145
• Species: Saccharomyces cerevisiae
• Alignment Length: 640
• Identity: 267/640 - (41%)
• Similarity: 406/640 - (63%)
• Gaps: 16/640 - (2%)

  Fly    37 NMGLMEQRERLPIRQYRDQILYCLEKHQVVILVGETGSGKSTQVPQYLYEWGWHTKGLIGITEPR 101
            ::.:..||:.||:...|.:::..:..:|.:::||||||||:||:.|||.|.|:...|:||.|:||
Yeast   473 SLPISAQRQTLPVYAMRSELIQAVRDNQFLVIVGETGSGKTTQITQYLDEEGFSNYGMIGCTQPR 537

  Fly   102 RVSTVTLANRVAQERGELVGDTVGYVVRFLESMSSCTKIKFMTEGILLREVLADPLLTQYGVIIV 166
            ||:.|::|.|||:|.|..||..|||.:||.:.....|:||:||:|:|.||.|.||.:::|.||::
Yeast   538 RVAAVSVAKRVAEEVGCKVGHDVGYTIRFEDVTGPDTRIKYMTDGMLQREALLDPEMSKYSVIML 602

  Fly   167 DEAHERNMLTDMILGLLKKILRKRSSLKLIISSATIDASFFSEFF-SWPGSGEVSVKLSIEGRMH 230
            ||||||.:.||::..||||...||..||:|::|||::::.|||:| :.|       .::|.|:..
Yeast   603 DEAHERTVATDVLFALLKKAAIKRPELKVIVTSATLNSAKFSEYFLNCP-------IINIPGKTF 660

  Fly   231 PVSNFYLNEPCADYVKETVETVWKLHQKEPPGDILAFLTGQEEVLEALDLLREYIASSEQE--NL 293
            ||...|...|..||::..::.|..:|..|.|||||.|||||||:....::|.:.:.:....  .|
Yeast   661 PVEVLYSQTPQMDYIEAALDCVIDIHINEGPGDILVFLTGQEEIDSCCEILYDRVKTLGDSIGEL 725

  Fly   294 KVLPMYGSMSSTDQLSVFFTPPKGTRKVVLATNIAETSITIPGIVYVIDCGYVKVKWYNPKTCSD 358
            .:||:|.::.|..|..:|...|||:||||.|||||||||||.||.||:|.|:.|:..||.:...:
Yeast   726 LILPVYSALPSEIQSKIFEPTPKGSRKVVFATNIAETSITIDGIYYVVDPGFAKINIYNARAGIE 790

  Fly   359 SLVIVPVSKASAIQRAGRAGRMRPGKVYRLYTKSD-YEALAPRQPPEMRRSELSGAILQLKALGI 422
            .|::.|:|:|.|.||.|||||..|||.|||||:|. |..:.....||::|..||..||.|||:||
Yeast   791 QLIVSPISQAQANQRKGRAGRTGPGKCYRLYTESAFYNEMLENTVPEIQRQNLSHTILMLKAMGI 855

  Fly   423 GNILRFDFPSPPPAQNLLSALESLFALDAIDEQGNLTKPVGYLLAELPFSAMLSKMLYVSGQMGC 487
            .::|:|||..|||...:|:||..|:.|.::|::|.||. :|..::..|....||:.|..|....|
Yeast   856 NDLLKFDFMDPPPKNLMLNALTELYHLQSLDDEGKLTN-LGKEMSLFPMDPTLSRSLLSSVDNQC 919

  Fly   488 SEEIITIIALLQVQSIFSRPASAVAQQSGRIAHRKFEVAEGDFITMLNAYTGFVEEGMTKEFCGQ 552
            |:||:|||::|.||::|.||.....:...:.|  ||....||.:|:||.||.:.:...::::|..
Yeast   920 SDEIVTIISMLSVQNVFYRPKDRQLEADSKKA--KFHHPYGDHLTLLNVYTRWQQANYSEQYCKT 982

  Fly   553 YFLIYRNLKRAHSLREQLITVARKKYGIPIFSCKGDVEKLCKCITAGFFTQVAYLHHSGVYRQIS 617
            .||.:|:||||..::.| |::..||.|:.:.||..|.:.:.|...:|||...|.......|:.|:
Yeast   983 NFLHFRHLKRARDVKSQ-ISMIFKKIGLKLISCHSDPDLIRKTFVSGFFMNAAKRDSQVGYKTIN 1046

  Fly   618 SGTELAIHPNSTLYTLPQAQYVVYGELLQTTKLFMNYVTVIKREWLTELAPHYYQ 672
            .|||:.|||:|:||. .:.:||:|..::.|::.:|:.||.|:.:||.|:|||:|:
Yeast  1047 GGTEVGIHPSSSLYG-KEYEYVMYHSIVLTSREYMSQVTSIEPQWLLEVAPHFYK 1100

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3225	NP_608860.1	HrpA	40..668	CDD:224557	263/631 (42%)
		DEXDc	64..202	CDD:238005	72/137 (53%)
		HELICc	289..380	CDD:197757	45/92 (49%)
		HA2	448..534	CDD:214852	30/85 (35%)
		OB_NTP_bind	<581..670	CDD:285018	32/88 (36%)
PRP22	NP_010929.3	Pnp	1..423	CDD:224106
		HrpA	456..1145	CDD:224557	267/640 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53574
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100085
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.720