Protein Alignment CG3225 and DHR2

DIOPT Version :10

• Sequence 1: NP_608860.1
• Gene: CG3225 / 33680
• FlyBaseID: FBgn0031631
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_012845.1
• Gene: DHR2 / 853784
• SGDID: S000001561
• Length: 735
• Species: Saccharomyces cerevisiae
• Alignment Length: 695
• Identity: 238/695 - (34%)
• Similarity: 391/695 - (56%)
• Gaps: 51/695 - (7%)

  Fly     7 KFLKPETDDAITDSAGGEQQSSAFVFNVNHNMGLMEQRERLPIRQYRDQILYCLEKHQVVILVGE 71
            ||......|.::|....::....:....:....|::.||.||:.|::.:|:..:|.:.|.:|:||
Yeast    41 KFNDSGEGDHVSDQRSNKENVLTYKSLKSRASDLLKMRETLPVYQHKREIMSYIESNPVTVLIGE 105

  Fly    72 TGSGKSTQVPQYLYEWGWHTK--GLIGITEPRRVSTVTLANRVAQERGELVGDTVGYVVRFLESM 134
            ||||||||:||::.|..:.||  |.|.:|:||||:.:.||.|||||.|..:|:.|||.|||..:.
Yeast   106 TGSGKSTQIPQFVLEKLYDTKKHGSIAVTQPRRVAAINLATRVAQEHGCKLGEQVGYSVRFDNTT 170

  Fly   135 SSCTKIKFMTEGILLREVLADPLLTQYGVIIVDEAHERNMLTDMILGLLKKILR-KRSSLKLIIS 198
            ::.|::|::|:|:||||::.:..|.:|.||::||||||.:|||:|||.||.::: .|..|::|:.
Yeast   171 TTRTRLKYLTDGMLLRELMMNSDLREYSVIVIDEAHERTVLTDLILGFLKSLIQGPRPDLRIIVM 235

  Fly   199 SATIDASFFSEFFSWPGSGEVSVKLSIEGRMHPVSNFYLNEPCADYVKETVETVWKLHQKEPPGD 263
            |||:.|..|||||:   :..:   |.:|||...|..:||..|..|.|...:....:::|.|..||
Yeast   236 SATLQAEKFSEFFN---NAPI---LFVEGRKFDVKQYYLKAPTDDIVDAVIRCCIQINQGEELGD 294

  Fly   264 ILAFLTGQEEVLEALDLLR---EYIASSEQENLKV-LPMYGSMSSTDQLSVFFTPPKG-TRKVVL 323
            ||.||.||||:.:|:.::.   :|::......|.| .|:|.::.:..| |:.|.|.|| .||||.
Yeast   295 ILCFLPGQEEIDKAVTIMEKIAKYVSDEAPVPLIVPYPLYAALPAVQQ-SLVFAPIKGFKRKVVF 358

  Fly   324 ATNIAETSITIPGIVYVIDCGYVKVKWYNPKTCSDSLVIVPVSKASAIQRAGRAGRMRPGKVYRL 388
            :|||||||:||.|:.:|:|.|..|||.:..:....:|:.||:|:|||:||:|||||...||.:||
Yeast   359 STNIAETSVTISGVKFVVDSGLRKVKVWRHQLGLATLLTVPISQASAMQRSGRAGRESEGKSFRL 423

  Fly   389 YTKSDYEALAPRQPPEMRRSELSGAILQLKALGIGNILRFDFPSPPPAQNLLSALESLFALDAID 453
            |.:|||..|..:..||:.||:::..:|.||..|:.::|.:.:...|..:.::..|:.|:.|.|:|
Yeast   424 YCESDYVKLPKQSEPEIARSDVTSPVLMLKRYGVDDLLNWTWFENPGKEAIVMGLQELYELGALD 488

  Fly   454 EQGNLTKPVGYLLAELPFSAMLSKMLYVSGQMGCSEEIITIIALLQVQSIFSRPASAVAQQSGRI 518
            .:|.:||. |..:|.||....||.:|..:.::||..::|.|::.|.|:::...|:   .::...:
Yeast   489 TRGKITKR-GQQMALLPLQPHLSSVLIKASEVGCLSQVIDIVSCLSVENLLLNPS---PEERDEV 549

  Fly   519 AHRKFEVAE-----GDFITMLNAY-TGFVEEGMTK-------EFCGQYFLIYRNLKRAHSLREQL 570
            ..|:..:..     ||.|.:...: ..|.|.|.::       ::|....:..|..|....:|:||
Yeast   550 NERRLSLCNAGKRYGDLIMLKELFDIYFYELGKSQDASSERNDWCKGLCISIRGFKNVIRVRDQL 614

  Fly   571 ITVARKKYGIPIFSCKGD--------------VEKLCKCITAGFFTQVAYLHHSGVYRQISSGTE 621
            ....::     :||...:              :.|:.||...||....|.......||.:|:|..
Yeast   615 RVYCKR-----LFSSISEEDEESKKIGEDGELISKILKCFLTGFIKNTAIGMPDRSYRTVSTGEP 674

  Fly   622 LAIHPNSTLYTLPQAQYVVYGELLQTTKLFMNYVTVIKREWLTEL 666
            ::|||:|.|:.......::|.|.:.|||.:...|:.|:..||.|:
Yeast   675 ISIHPSSMLFMNKSCPGIMYTEYVFTTKGYARNVSRIELSWLQEV 719

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3225	NP_608860.1	HrpA	38..>669	CDD:441249	234/664 (35%)
DHR2	NP_012845.1	HrpA	79..>534	CDD:441249	190/462 (41%)
		OB_NTP_bind	645..722	CDD:400182	24/75 (32%)