DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3225 and AT3G62310

DIOPT Version :9

Sequence 1:	NP_608860.1	Gene:	CG3225 / 33680	FlyBaseID:	FBgn0031631	Length:	678	Species:	Drosophila melanogaster
Sequence 2:	NP_191790.1	Gene:	AT3G62310 / 825404	AraportID:	AT3G62310	Length:	726	Species:	Arabidopsis thaliana

Alignment Length:	660	Identity:	268/660 - (40%)
Similarity:	410/660 - (62%)	Gaps:	48/660 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 LMEQRERLPIRQYRDQILYCLEKHQVVILVGETGSGKSTQVPQYLYE------------WGWHTK 92
            ::|:|..||:...:::.|..|..:|.:||||||||||:||:||::.:            |
plant    54 ILEKRRTLPVWLQKEEFLKTLNNNQTLILVGETGSGKTTQIPQFVIDAVDAETSDKRRKW----- 113

  Fly    93 GLIGITEPRRVSTVTLANRVAQERGELVGDTVGYVVRFLESMSSCTKIKFMTEGILLREVLADPL 157
             |:|.|:||||:.::::.|||:|....:|:.|||.:||.:..|..|.:|::|:|:||||.:||||
plant   114 -LVGCTQPRRVAAMSVSRRVAEEMDVTIGEEVGYSIRFEDCSSPRTVLKYLTDGMLLREAMADPL 177

  Fly   158 LTQYGVIIVDEAHERNMLTDMILGLLKKILRKRSSLKLIISSATIDASFFSEFFSWPGSGEVSVK 222
            |.:|.|||:||||||.:.||::.||||::|:.|..|||::.|||::|..|.::|    ||...:|
plant   178 LERYKVIILDEAHERTLATDVLFGLLKEVLKNRPDLKLVVMSATLEAEKFQDYF----SGAPLMK 238

  Fly   223 LSIEGRMHPVSNFYLNEPCADYVKETVETVWKLHQKEPPGDILAFLTGQEEVLEALDLLREYIAS 287
              :.||:|||..||..||..||::..:.||.::|..|||||||.||||:||:.:|...:.:.:.:
plant   239 --VPGRLHPVEIFYTQEPERDYLEAAIRTVVQIHMCEPPGDILVFLTGEEEIEDACRKINKEVGN 301

  Fly   288 --SEQENLKVLPMYGSMSSTDQLSVFFTPPKGT-------RKVVLATNIAETSITIPGIVYVIDC 343
              .:...:||:|:|.::....|..:|...|:..       ||:|::|||||||:||.|||||||.
plant   302 LGDQVGPIKVVPLYSTLPPAMQQKIFDPAPEPVTEGGPPGRKIVVSTNIAETSLTIDGIVYVIDP 366

  Fly   344 GYVKVKWYNPKTCSDSLVIVPVSKASAIQRAGRAGRMRPGKVYRLYT-KSDYEALAPRQPPEMRR 407
            |:.|.|.|||:...:||::.|:|||||.||:|||||.||||.:|||| ||....|.|:..||:.|
plant   367 GFAKQKVYNPRIRVESLLVSPISKASAHQRSGRAGRTRPGKCFRLYTEKSFNNDLQPQTYPEILR 431

  Fly   408 SELSGAILQLKALGIGNILRFDFPSPPPAQNLLSALESLFALDAIDEQGNLTKPVGYLLAELPFS 472
            |.|:..:|.||.|||.:::.|||..||..:.|:.|||.|..|.|:|:.||||| .|.:::|.|..
plant   432 SNLANTVLTLKKLGIDDLVHFDFMDPPAPETLMRALEVLNYLGALDDDGNLTK-TGEIMSEFPLD 495

  Fly   473 AMLSKMLYVSGQMGCSEEIITIIALLQVQSIFSRPASAVAQQSGRIAHRKFEVAEGDFITMLNAY 537
            ..::|||.||.:..||.||:::.|:|.|.:.|.||..  ||::...|..:|...|||.:|:||.|
plant   496 PQMAKMLIVSPEFNCSNEILSVSAMLSVPNCFIRPRE--AQKAADEAKARFGHIEGDHLTLLNVY 558

  Fly   538 TGFVEEGMTKEFCGQYFLIYRNLKRAHSLREQLITVARKKYGIPIFSCKGDVE------KLCKCI 596
            ..|.:......:|.:.|:..|.:|.|.::|:||:.: ..::.:.:  |..|..      .:.|.:
plant   559 HAFKQNNEDPNWCYENFINNRAMKSADNVRQQLVRI-MSRFNLKM--CSTDFNSRDYYINIRKAM 620

  Fly   597 TAGFFTQVAYLHHSGVYRQISSGTELAIHPNSTLYTLPQAQYVVYGELLQTTKLFMNYVTVIKRE 661
            .||:|.|||:|..:|.|..:.....:.:||::.|...|  ::|:|.|.:.|::.|:..||.|:.|
plant   621 LAGYFMQVAHLERTGHYLTVKDNQVVHLHPSNCLDHKP--EWVIYNEYVLTSRNFIRTVTDIRGE 683

  Fly   662 WLTELAPHYY 671
            ||.::|.|||
plant   684 WLVDVASHYY 693

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3225	NP_608860.1	HrpA	40..668	CDD:224557	264/655 (40%)
		DEXDc	64..202	CDD:238005	70/149 (47%)
		HELICc	289..380	CDD:197757	46/97 (47%)
		HA2	448..534	CDD:214852	34/85 (40%)
		OB_NTP_bind	<581..670	CDD:285018	28/94 (30%)
AT3G62310	NP_191790.1	DEXDc	66..249	CDD:214692	84/194 (43%)
		DEXDc	80..222	CDD:238005	69/147 (47%)
		HELICc	247..411	CDD:238034	74/163 (45%)
		DUF3206	411..>492	CDD:256473	37/81 (46%)
		HA2	472..555	CDD:214852	34/85 (40%)
		OB_NTP_bind	589..692	CDD:285018	30/107 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53574
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100085
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.730