Protein Alignment CG3225 and dhx8

DIOPT Version :10

• Sequence 1: NP_608860.1
• Gene: CG3225 / 33680
• FlyBaseID: FBgn0031631
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: XP_002932570.2
• Gene: dhx8 / 733563
• XenbaseID: XB-GENE-6087171
• Length: 1181
• Species: Xenopus tropicalis
• Alignment Length: 656
• Identity: 286/656 - (43%)
• Similarity: 422/656 - (64%)
• Gaps: 22/656 - (3%)

  Fly    22 GGEQQSSAFVFNVNHNMGLMEQRERLPIRQYRDQILYCLEKHQVVILVGETGSGKSTQVPQYLYE 86
            ||.:.|    :.....|.::||||.|||.:.::|::..:..:|::|::|||||||:||:.|||.|
 Frog   505 GGNKAS----YGKKTQMSIVEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAE 565

  Fly    87 WGWHTKGLIGITEPRRVSTVTLANRVAQERGELVGDTVGYVVRFLESMSSCTKIKFMTEGILLRE 151
            .|:.|:|.||.|:||||:.:::|.||::|.|..:|..|||.:||.:..|..|.||:||:|:||||
 Frog   566 AGYTTRGKIGCTQPRRVAAMSVAKRVSEEYGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRE 630

  Fly   152 VLADPLLTQYGVIIVDEAHERNMLTDMILGLLKKILRKRSSLKLIISSATIDASFFSEFFSWPGS 216
            .|.||.||||.:|::||||||.:.||::.|||||.::||..:|||::|||:||..||::|.
 Frog   631 CLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRPDMKLIVTSATLDAVKFSQYFY---- 691

  Fly   217 GEVSVKLSIEGRMHPVSNFYLNEPCADYVKETVETVWKLHQKEPPGDILAFLTGQEEVLEALDLL 281
             |..: .:|.||.:||...|..||..||:..::.||.::|..|||||||.|||||||:..|.::|
 Frog   692 -EAPI-FTIPGRTYPVEILYTKEPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEIL 754

  Fly   282 REYIAS--SEQENLKVLPMYGSMSSTDQLSVFFTPPKGTRKVVLATNIAETSITIPGIVYVIDCG 344
            .|.:.|  .:...|.:||:|.::.|..|..:|...|.|:||||:||||||||:||.||.||:|.|
 Frog   755 YERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPG 819

  Fly   345 YVKVKWYNPKTCSDSLVIVPVSKASAIQRAGRAGRMRPGKVYRLYTKSDY-EALAPRQPPEMRRS 408
            :||.|.||.||..|.||:.|:|:|.|.||||||||..|||.|||||:..| :.:.....||::|:
 Frog   820 FVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRT 884

  Fly   409 ELSGAILQLKALGIGNILRFDFPSPPPAQNLLSALESLFALDAIDEQGNLTKPVGYLLAELPFSA 473
            .|:..:|.|||:||.::|.|||...||.:.|::|:|.|:.|.|:|::|.||: :|..:||.|...
 Frog   885 NLASTVLSLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTR-LGRRMAEFPLEP 948

  Fly   474 MLSKMLYVSGQMGCSEEIITIIALLQVQSIFSRP--ASAVAQQSGRIAHRKFEVAEGDFITMLNA 536
            ||.|||.:|..:|||||::||:::|.||::|.||  ..|:|.|.    ..||...|||.:|:|..
 Frog   949 MLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQK----KAKFHQTEGDHLTLLAV 1009

  Fly   537 YTGFVEEGMTKEFCGQYFLIYRNLKRAHSLREQLITVARKKYGIPIFSCKGDVEKLCKCITAGFF 601
            |..:.....:..:|.:.|:..|:|:||..:|:|::.: ..::.:.:.||.....::.|.|.:|||
 Frog  1010 YNSWKNNKFSNPWCYENFIQARSLRRAQDIRKQMLGI-MDRHKLDVVSCGKATVRVQKAICSGFF 1073

  Fly   602 TQVAYLHHSGVYRQISSGTELAIHPNSTLYTLPQAQYVVYGELLQTTKLFMNYVTVIKREWLTEL 666
            ...|.......||.:.....:.|||:|.|:. .|.::|||.||:.|||.:|..||.|...||.|.
 Frog  1074 RNAAKKDPQEGYRTLIDQQVVYIHPSSALFN-RQPEWVVYHELVLTTKEYMREVTTIDPRWLVEF 1137

  Fly   667 APHYYQ 672
            ||.:::
 Frog  1138 APAFFK 1143

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3225	NP_608860.1	HrpA	38..>669	CDD:441249	282/635 (44%)
dhx8	XP_002932570.2	GH2-like_DHX8	12..79	CDD:409668
		S1_DHX8_helicase	226..304	CDD:240189
		HrpA	517..>1148	CDD:441249	283/640 (44%)