Protein Alignment CG3225 and Dhx35

DIOPT Version :10

• Sequence 1: NP_608860.1
• Gene: CG3225 / 33680
• FlyBaseID: FBgn0031631
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_001359442.1
• Gene: Dhx35 / 71715
• MGIID: 1918965
• Length: 703
• Species: Mus musculus
• Alignment Length: 696
• Identity: 332/696 - (47%)
• Similarity: 472/696 - (67%)
• Gaps: 42/696 - (6%)

  Fly     7 KFLKPETD----------DAITDSAGGEQQSSAFVFNVNHNMGLMEQRERLPIRQYRDQILYCLE 61
            ||.||.|:          .::|:::|     :..::|....:.:.:||::||:.:.|:.|||.:|
Mouse     9 KFWKPGTEGPGVSISEERQSVTENSG-----TTIIYNPYAALSIEQQRQKLPVFKLRNHILYLVE 68

  Fly    62 KHQVVILVGETGSGKSTQVPQYLYEWGWHTKG-LIGITEPRRVSTVTLANRVAQERGELVGDTVG 125
            .:|.|::|||||.|||||:||||.|.||..:| ::|:|:||||:.||:|.|||.|||.::|..||
Mouse    69 NYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVADERGAVLGHEVG 133

  Fly   126 YVVRFLESMSSC-----TKIKFMTEGILLREVLADPLLTQYGVIIVDEAHERNMLTDMILGLLKK 185
            |.:||    ..|     |:|||:|:|:|:||::.|||||:|.||::||||||.:.||:.:|||||
Mouse   134 YCIRF----DDCTDPLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKK 194

  Fly   186 ILRKRSSLKLIISSATIDASFFSEFFSWPGSG----EVSVKLSIEGRMHPVSNFYLNEPCADYVK 246
            |.:||..|:||::|||:||..|.:||:...:.    :.||.|::|||..||..|||..|..||:|
Mouse   195 IQKKRGDLRLIVASATLDAEKFRDFFNQNETSDPARDTSVTLTVEGRTFPVDIFYLQSPVPDYIK 259

  Fly   247 ETVETVWKLHQKEPPGDILAFLTGQEEVLEALDLL----REYIASSEQENLKVLPMYGSMSSTDQ 307
            .||:||.|:||.|..|||||||||||||...:.:|    |....:..:::|:|||||..:.|.:|
Mouse   260 ATVDTVVKIHQTEGDGDILAFLTGQEEVETVVSMLIEQARALARTGMKKHLRVLPMYAGLPSFEQ 324

  Fly   308 LSVFFTPPKGTRKVVLATNIAETSITIPGIVYVIDCGYVKVKWYNPKTCSDSLVIVPVSKASAIQ 372
            :.||.......|||::|||:|||||||.|||||||||::|::.|||:|..:.||:||||:|||.|
Mouse   325 MKVFERVSHSVRKVIVATNVAETSITISGIVYVIDCGFMKLRAYNPRTAIECLVVVPVSQASANQ 389

  Fly   373 RAGRAGRMRPGKVYRLYTKSDYEALAPRQPPEMRRSELSGAILQLKALGIGNILRFDFPSPPPAQ 437
            ||||.||.|.||.|||||:..::.|.....|||:||.|:..|||||||||.|:|||.|.||||||
Mouse   390 RAGRGGRNRSGKCYRLYTEEAFDQLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQ 454

  Fly   438 NLLSALESLFALDAIDEQGNLTKPVGYLLAELPFSAMLSKMLYVSGQMGCSEEIITIIALLQVQS 502
            :::.|||.|:||..:|:...||:|:|..:||.|.:.|.:|||..||..|||:|:::|.|::|:|:
Mouse   455 SMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEVLSIAAMMQIQN 519

  Fly   503 IFSRPASAVAQQSGRIAHRKFEVAEGDFITMLNAYTGFVEEGMTKEFCGQYFLIYRNLKRAHSLR 567
            :|..|::..:|.: |: ||||.|.|||.:||||.|..|::...:.::|.::||.|:.|.||.::|
Mouse   520 VFVFPSNQKSQAT-RV-HRKFAVEEGDHLTMLNVYEAFIKHNKSSQWCQEHFLNYKGLVRAATVR 582

  Fly   568 EQLITVARK---KYGIPIFSCKGDVEKLCKCITAGFFTQVAYLHHSGVYRQISSGTELAIHPNST 629
            :||    :|   |:.:|..|.:||.:.:.:||.:|||...|..|.||.||.|....||.|||.|.
Mouse   583 DQL----KKLLVKFQVPKVSSEGDPDPVLRCIVSGFFANAARFHSSGAYRTIRDDHELHIHPASV 643

  Fly   630 LYTLPQAQYVVYGELLQTTKLFMNYVTVIKREWLTELAPHYYQQTT 675
            ||.....::|:|.|::||:|.:|..||.|:..||.|||||:|||.|
Mouse   644 LYAEKPPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQQGT 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3225	NP_608860.1	HrpA	38..>669	CDD:441249	318/647 (49%)
Dhx35	NP_001359442.1	HrpA	54..>701	CDD:441249	322/646 (50%)