| Sequence 1: | NP_608860.1 | Gene: | CG3225 / 33680 | FlyBaseID: | FBgn0031631 | Length: | 678 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_064547.2 | Gene: | DHX33 / 56919 | HGNCID: | 16718 | Length: | 707 | Species: | Homo sapiens |
| Alignment Length: | 643 | Identity: | 268/643 - (41%) |
|---|---|---|---|
| Similarity: | 384/643 - (59%) | Gaps: | 24/643 - (3%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 43 QRERLPIRQYRDQILYCLEKHQVVILVGETGSGKSTQVPQYLYEWGWHTKGLIGITEPRRVSTVT 107
Fly 108 LANRVAQERGELVGDTVGYVVRFLESMSSCTKIKFMTEGILLREVLADPLLTQYGVIIVDEAHER 172
Fly 173 NMLTDMILGLLKKILRKRSS-----LKLIISSATIDASFFSEFFSWPGSGEVSVKLSIEGRMHPV 232
Fly 233 SNFYLNEPCADYVKETVETVWKLHQKEPPG-DILAFLTGQEEVLEALDLLREYIASSEQEN---L 293
Fly 294 KVLPMYGSMSSTDQLSVFFTPPKGTRKVVLATNIAETSITIPGIVYVIDCGYVKVKWYNPKTCSD 358
Fly 359 SLVIVPVSKASAIQRAGRAGRMRPGKVYRLYTKSDYEALAPRQPPEMRRSELSGAILQLKALGIG 423
Fly 424 NILRFDF---PSPPPAQNLLSALESLFALDAIDEQGNLTKPVGYLLAELPFSAMLSKMLYVSGQM 485
Fly 486 GCSEEIITIIALLQVQSIFSRPASAVAQQSGRIAHRKFEVAEGDFITMLNAYTGFVEEGMTKEFC 550
Fly 551 GQYFLIYRNLKRAHSLREQLITVARKKYGIPIFSCKGDVEKLCKCITAGFFTQVAYLHHSGVYRQ 615
Fly 616 ISSGTELAIHPNSTLYTLPQAQYVVYGELLQTTKLFMNYVTVIKREWLTELAPHYYQQ 673 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG3225 | NP_608860.1 | HrpA | 40..668 | CDD:224557 | 265/636 (42%) |
| DEXDc | 64..202 | CDD:238005 | 68/142 (48%) | ||
| HELICc | 289..380 | CDD:197757 | 48/93 (52%) | ||
| HA2 | 448..534 | CDD:214852 | 31/85 (36%) | ||
| OB_NTP_bind | <581..670 | CDD:285018 | 36/88 (41%) | ||
| DHX33 | NP_064547.2 | Required for nucleolar location. /evidence=ECO:0000269|PubMed:26100019 | 1..80 | 6/9 (67%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..64 | ||||
| HrpA | 67..695 | CDD:224557 | 265/636 (42%) | ||
| DEXDc | 92..234 | CDD:238005 | 68/141 (48%) | ||
| DEAH box | 194..197 | 2/2 (100%) | |||
| Helicase_C | 291..408 | CDD:278689 | 60/117 (51%) | ||
| HA2, required for interaction with EIF3G and RPL26. /evidence=ECO:0000269|PubMed:26100019 | 471..562 | 32/93 (34%) | |||
| HA2 | 478..563 | CDD:214852 | 32/87 (37%) | ||
| Critical for rDNA-binding. /evidence=ECO:0000250 | 547..558 | 4/12 (33%) | |||
| OB_NTP_bind | 597..697 | CDD:285018 | 39/101 (39%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG1643 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG53574 | |
| OrthoDB | 1 | 1.010 | - | - | D354219at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000059 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_100085 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 6 | 5.730 | |||||