Protein Alignment CG3225 and Dhx33

DIOPT Version :10

• Sequence 1: NP_608860.1
• Gene: CG3225 / 33680
• FlyBaseID: FBgn0031631
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_001099272.1
• Gene: Dhx33 / 287464
• RGDID: 1307239
• Length: 698
• Species: Rattus norvegicus
• Alignment Length: 644
• Identity: 266/644 - (41%)
• Similarity: 388/644 - (60%)
• Gaps: 26/644 - (4%)

  Fly    43 QRERLPIRQYRDQILYCLEKHQVVILVGETGSGKSTQVPQYLYEWGWHTKGLIGITEPRRVSTVT 107
            ||..|||.:.|.|:|..|......:|:|||||||:||:||||||.|...:|:|.:|:||||:.::
  Rat    61 QRRSLPIFRARGQLLAQLRNLDNAVLIGETGSGKTTQIPQYLYEGGISRQGIIAVTQPRRVAAIS 125

  Fly   108 LANRVAQERGELVGDTVGYVVRFLESMSSCTKIKFMTEGILLREVLADPLLTQYGVIIVDEAHER 172
            ||.||:.|:...:|..|||.|||.:..|..|:|||:|:|:||||.::|.||.:|..:|:||||||
  Rat   126 LATRVSDEKRTELGKLVGYTVRFEDVTSEDTRIKFLTDGMLLREAISDSLLRKYSCVILDEAHER 190

  Fly   173 NMLTDMILGLLKKILRKRSS-----LKLIISSATIDASFFSEFFSWPGSGEVSVKLSIEGRMHPV 232
            .:.||::.|::|...::|..     ||:|:.|||:|...||::|:.      :..|.:|||.||:
  Rat   191 TIHTDVLFGVVKTAQKRRKELGKLPLKVIVMSATMDVDLFSQYFNG------APVLYLEGRQHPI 249

  Fly   233 SNFYLNEPCADYVKETVETVWKLHQKEPPG-DILAFLTGQEEVLEALDLLREYIASSEQE---NL 293
            ..||..:|..||:...:.:|:::||:.|.. |||.|||||||: ||:......||....:   ::
  Rat   250 QIFYTKQPQQDYLHAALVSVFQIHQEAPSSQDILVFLTGQEEI-EAMSKTCRDIAKHLPDGCPSM 313

  Fly   294 KVLPMYGSMSSTDQLSVFFTPPKGTRKVVLATNIAETSITIPGIVYVIDCGYVKVKWYNPKTCSD 358
            .|||:|.|:..:.||.||...|||.|||:::||||||||||.||.||:|.|.||.|.|||.:..:
  Rat   314 LVLPLYASLPYSQQLRVFQGAPKGYRKVIISTNIAETSITITGIKYVVDTGMVKAKKYNPDSGLE 378

  Fly   359 SLVIVPVSKASAIQRAGRAGRMRPGKVYRLYTKSDYEALAPRQPPEMRRSELSGAILQLKALGIG 423
            .|.:..|||..|.||.|||||...|..|||||:.:::.......||::|..|:..:|||.|:.:.
  Rat   379 VLAVQRVSKTQAWQRTGRAGREDSGICYRLYTEDEFDKFEKMAAPEIQRCNLASVMLQLLAMKVP 443

  Fly   424 NILRFDF---PSPPPAQNLLSALESLFALDAIDEQGNLTKPVGYLLAELPFSAMLSKMLYVSGQM 485
            |:|.|||   |||...:..::.|:.|.||:..|:|..|| |:|..:|..|.....:|.:.:|.:.
  Rat   444 NVLTFDFMSRPSPDHIEAAIAQLDLLGALEHKDDQLALT-PIGRKMAAFPLEPKFAKTILLSSKF 507

  Fly   486 GCSEEIITIIALLQVQSI-FSRPASAVAQQSGRIAHRKFEVAEGDFITMLNAYTGFVEEGMTKEF 549
            .|:|||:||::||.|.|: ::.||.....||.|   :||..:|||.||:||.|..|...|..|::
  Rat   508 HCTEEILTIVSLLSVDSVLYNPPARRDEVQSVR---KKFISSEGDHITLLNIYRTFKNIGGNKDW 569

  Fly   550 CGQYFLIYRNLKRAHSLREQLITVARKKYGIPIFSCKGDVEKLCKCITAGFFTQVAYLHHSGVYR 614
            |.:.|:..:|:.....:|.||..:. .|..:||.|.:||:|.:.:|:....|...|.|...|.|.
  Rat   570 CKENFVNSKNMLLVAEVRAQLRDIC-LKMSMPIMSSRGDMESVRRCLAHSLFMSTAELQPDGTYA 633

  Fly   615 QISSGTELAIHPNSTLYTLPQAQYVVYGELLQTTKLFMNYVTVIKREWLTELAPHYYQQ 673
            ...:...:||||:|.|:....| .|||..||.|.|.:|..:.|:..|||.|.||.|:::
  Rat   634 TTDTHQPVAIHPSSVLFHCKPA-CVVYTSLLYTNKCYMRDLCVVDAEWLYEAAPDYFRR 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3225	NP_608860.1	HrpA	38..>669	CDD:441249	264/638 (41%)
Dhx33	NP_001099272.1	HrpA	64..>534	CDD:441249	206/477 (43%)
		OB_NTP_bind	611..688	CDD:400182	28/77 (36%)